Term
|
Definition
cholinergic agonist
affects N and M type chol. receptors |
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Term
|
Definition
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Term
|
Definition
Where: preganglia, adrenal medulla, skeletal muscle (NMJ)
=ligand-gated ion |
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Term
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Definition
| Where: sweat glands (S); (P)- cardiac, smooth, gland, nerve |
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Term
|
Definition
M type chol. agonist
=GPCR |
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Term
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Definition
| blocks ACh vesicle docking |
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Term
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Definition
| Competitive nicotinic antagonist (M TYPE) |
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Term
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Definition
chol. Nicotinic (M TYPE ONLY) agonist/antagonist
quick acting (5-8 minutes) |
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Term
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Definition
| same as tubocurare but acts in 20-35 min. |
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Term
| Muscarinic Receptor Breakdown |
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Definition
1,3,5- up calcium- contract
2,4- down cAMP- ALSO CONTRACT but mediated by NO in the body |
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Term
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Definition
muscarinic agonist
postop urogenic drug |
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Term
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Definition
| muscarinic competitive antagonist |
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Term
|
Definition
Alcohol type (edrophonium)- reversible
Carbamate type (neostigmine)- reversible
Organophosphate type- irreversible |
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Term
| Cholinesterase reactivator |
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Definition
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Term
|
Definition
| parathion, malathion, tabun, sarin |
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Term
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Definition
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Term
|
Definition
| increase calcium, increase contraction |
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Term
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Definition
| increase cAMP, decrease contraction |
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Term
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Definition
| muscarinic antagonist (like atropine) but inhaled so only the lung response. |
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Term
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Definition
| decrease cAMP, promote contraction |
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Term
|
Definition
beta 2 agonist
bronchodilation |
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Term
|
Definition
| beta 1 AND 2 competitive antagonist |
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Term
|
Definition
| alpha (mostly 1) agonist- degongestant (some mydriasis and increase blood pressure) |
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Term
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Definition
| alpha (both) competitive antagonists |
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