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Drug Rxns & Skin Findings in Systemic Diseases
Pictures from Systemic Skin Diseases p41-48
40
Biology
Professional
12/05/2010

Additional Biology Flashcards

 


 

Cards

Term
[image]
Definition

 

 

Maculopapular

"Morbilliform" (exanthem-like)

 

Macule: non-palpable, circumscribed, flat, discoloration, <1cm

Papule: An ELEVATED solid lesion, <1cm

 

Term
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Definition

 

Maculopapular

"Morbilliform" (exanthem-like)

 

Macule: non-palpable, circumscribed, flat, discoloration, <1cm

Papule: An ELEVATED solid lesion, <1cm

 

Term
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Definition

 

 

Urticaria

Term
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Definition

 

 

Dermographism


sometimes assoc. w/ urticaria or systemic itching

Term
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Definition

 

 

Fixed Drug Eruption

 

annular or oval erythematous patches;

resolves w/ hyperpigmentation

Term
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Definition

 

Fixed Drug Eruption

 

annular or oval erythematous patches;

resolves w/ hyperpigmentation

Term
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Definition

 

Fixed Drug Eruption

 

annular or oval erythematous patches;

resolves w/ hyperpigmentation

Term
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Definition

 

Erythema Multiforme

 

Think "Target Lesion": central papule w/ 2+ concentric erythematous rings. Most common cause: HSV

Term
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Definition

 

Erythema Multiforme

 

Think "Target Lesion": central papule w/ 2+ concentric erythematous rings. Most common cause: HSV

Term
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Definition

 

Steven Johnson Syndrome

 

Prodrome: URI, fever, painful skin

BSA: <10% 

mortality rate: 1-5%

Term
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Definition

 

 

Steven Johnson Syndrome

 

Prodrome: URI, fever, painful skin

BSA: <10% 

mortality rate: 1-5%

 

Term
[image]
Definition

 

Toxic Epidermal Necrolysis

 

Nikolsky's sign: skin slides off with gentle tangential pressure! 

BSA: >30%

Mortality rate: 25-35%

Term
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Definition

 

Toxic Epidermal Necrolysis

 

Nikolsky's sign: skin slides off with gentle tangential pressure! 

BSA: >30%

Mortality rate: 25-35%

Term
[image]
Definition

 

Malar Rash

(Acute Lupus)

 

dsDNA antibodies

Term
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Definition

 

Subacute Cutaneous LE

 

anti-Ro antibodies

NO systemic involvement

Term
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Definition

 

Discoid Lupus

 

Favors arms and face

Heals w/ scar

<10% have systemic involvement

Term
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Definition

 

Shawl Sign

(Dermatomyositis)

 

photodistributed violaceous poikiloderma [patches of hypo/hyperpigmentation, telangiectasia, epidermal atrophy]

Term
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Definition

 

Shawl Sign and Photosensitivity 

 

(Dermatomyositis)

Term
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Definition

 

Gottron's Papules 

scaly or lichenified papules/plaques over joints of the hands

 

(Dermatomyositis)

Term
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Definition

 

Periungunal Telangiectasias

visible dilated capillary loops around nails

 

(Dermatomyositis)

Term
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Definition

 

Sarcoid

Term
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Definition

 

Sarcoid

Term
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Definition

 

Lupus Pernio

red/brown non-scaly papules & nodules around the eyes, nose or mouth

 

(Sarcoid)

Term
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Definition

 

Sarcoid

 

(mimicking Vitiligo)

Term
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Definition

 

Erythema Nodosum

 

-most common NON-specific, NON-granulomatous skin finding in Sarcoidosis

-Panniculitis (inflammation of fat tissue)

Term
[image]
Definition

 

Cutaneous T-Cell Lymphoma

Patch Stage

Term
[image]
Definition

 

Cutaneous T-Cell Lymphoma

 

Patch/Plaques 

Term
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Definition

 

Cutaneous T-Cell Lymphoma

 

Tumor

Term
[image]
Definition

 

Erythroderma/Sézary

 

(CTCL)

Term
[image]
Definition

 

Pyoderma Grangrenosum

 

Painful Ulcers

Do not debride!!!

Term
[image]
Definition

 

 

Café-Au-lait macules

 

(Neurofibromatosis-Type 1 (NF1) )

 

Term
[image]
Definition

 

Neurofibromas

 

(Neurofibromatosis-Type 1 (NF1) )

Term
[image]
Definition

 

Lisch Nodules

 

(Neurofibromatosis-Type 1 (NF1) )

Term
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Definition

 

Crowe's Sign

Freckling in the axillae & groin

 

(Neurofibromatosis-Type 1 (NF1) )

Term
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Definition

 

Plexiform Neurofibroma

 

(Neurofibromatosis-Type 1 (NF1) )

Term
[image]
Definition

 

Ash Leaf Macules

 

(Tuberous Sclerosis)

Term
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Definition

 

Facial Angiofibromas

 

(Tuberous Sclerosis)

Term
[image]
Definition

 

Shagreen Patch 

 

(Tuberous Sclerosis)

Term
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Definition

 

 

Periungual Fibromas

'Koenene tumors'

 

(Tuberous Sclerosis)

Term
[image]
Definition

 

 

Vitiligo

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