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Drug quiz #4
Opthalmic, ottic, pain
144
Pharmacology
Graduate
02/15/2011

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Term
Infliximab's brand name
Definition
remicade
Term
Infliximab/remicade indication
Definition
Crohn's disease, ulcerative colitus, RA, Psoriatic arthritis, ankylosing spondylitis
Term
How is Infliximab supplied?
Definition
100mg/20ml IV
Term
Normal dosing and RA dosing for Infliximab
Definition
Normal: 5mg/kg wks 0, 2, 6 then every 8 wks
RA: 3mg/kg wks 0,2,6 then every 8wks WITH methotrexate
Term
Remicade/infliximab contraindication and BlackBox warning
Definition
Heart Failure BB: serious infections (TB, sepsis etc) and malignency
Term
Remicade drug interactions
Definition
Infliximab administered with Anakinra leads to increased risk of infection
Live vaccines
Term
Remicade/infliximab side effects
Definition
infection (URI), infusion rxn, headache, abdominal pain
Term
Remicade's generic name
Definition
Infliximab
Term
Orphenadrine Citrate Brand name
Definition
Norflex
Term
Norflex generic name
Definition
Orphenadrine Citrate
Term
Norflex/Orphenadrine Indication
Definition
Musculoskeletal pain
Term
How is Norlfex supplied?
Definition
60mg/2ml single dose vial for IM or IV injection and 100mg tablet
Term
Norflex dose
Definition
60mg IV or IM q12 hours OR 100mg po BID
Term
Norflex contraindications
Definition
Glaucoma, bowel or bladder obstruction, BPH, cardio spasm, myasthenia gravis, stenosing peptic ulcer
Term
Norflex side effects
Definition
Tachycardia/palpitations, dry mouth, urinary retention, increased occular tension (thus contraindications)
Term
What is Tramadol's brand name?
Definition
Ultram
Term
What is Ultram's generic name
Definition
Tramadol
Term
What is tramadol's indication?
Definition
Moderate to moderate-severe pain
Term
What is tramadol's dosing
Definition
50-100mg q4-6h (max 400mg/day) (titrate onto drug)
Term
Tramadol Drug interactions
Definition
SSRI, triptans, carbamazepine, ketaconazole, erythromycin, rifamin, st. john's wort, quinidine
Term
What is Pentazocine Lactate's brand name?
Definition
Talwin
Term
What is Talwin's generic name?
Definition
Pentazocine Lactate
Term
What is Talwin/Pentazocine's indication
Definition
Moderate to severe pain
Term
How is Talwin/Pentazocine supplied?
Definition
30mg/ml concentration in 1ml ampules or 10ml multi-dose vial. Administer IV, IM, or SQ
Term
What is the dosing for Talwin/Pentazocine
Definition
30mg (1ml) IV/IM/SQ q3-4h (Max daily dose = 360mg)
Term
What is Nalbuphine's brand name?
Definition
Nubian
Term
What is Nubian's generic name?
Definition
Nalbuphine
Term
Indications for Nubian
Definition
Periopertive and Postoperative analgesia, Obsteric analgesia and Moderate to Severe pain
Term
How is Nubian/Nalbuphine supplied?
Definition
10mg/ml and 20mg/ml concentrations in 1ml ampules or 10ml multi-dose vials
Term
Dose for Nubian/Nalbuphine
Definition
10mg IV/IM/SQ every 3-6 hours as needed
Term
Nubian/Nalbuphine drug inderactions
Definition
additive effects when administered with other CNS depressants
Term
Nubian/Nalbuphine side effects
Definition
(CNS dep) Sedation, N/V, Dizzy, dry mouth, headache, sweaty/clammy
Term
What is the brand name for Butorphanol
Definition
Stadol
Term
what is butorphanol/stadol indicated for?
Definition
Periopertive and preanesthetic pain
Term
How is Stadol/butorphanol supplied?
Definition
1mg/ml and 2mg/ml vials for IV or IM administration
Term
What is dose of Stadol/Butorphanol IM?
" " IV?
Definition
IM: 1-4mg q3-4h
IV: 1mg q3-4h
Term
What is the pre-anasthesia dose for Stadol/butorphanol?
Definition
Preanasthesia: 2mg 60-90min prior to surgery
Term
What contraindiactions does Stadol have?
Definition
Benzethonium Cl hypersensitivity (a preservative)
Term
What drug interactions are there with Stadol/butorphanol
Definition
Alcohol, barbiturates, antihistamines, tranquilizers
Term
What are the side effects of Standol/butorphanol
Definition
Somnolence, N/V, dizzyness
Term
What is the brand name for Ketorolac?
Definition
Toradol
Term
What is generic name for Toradol?
Definition
Ketorolac
Term
What is Toradol indicated for?
Definition
Acute moderate to severe pain (less than 5 days)
Term
How is Toradol supplied?
Definition
15mg/ml and 30mg/ml for IV or IM injection
60mg/2ml for IM injection ONLY
Term
What is the normal IM dose for Toradol?
What is the normal IV dose for Toradol?
Definition
IM: 60mg/day Renal or <50kg IM: 30mg/day
IV: 30mg/day Renal or <50kg or >65yo IV: 15mg q6h
Term
What are the contraindications for Toradol?
Definition
Tromethamine, NSAID hypersensativity, nursing, GI bleed or GI perforation
Term
What drug interactions are associated with Toradol?
Definition
Salicylates, NSAIDs, furosemide, thiazides (diuretics), probenecid, lithium, methotrexate, antiepeleptics, psychoactive drugs, pentoxafyline, muscle relaxants and SSRIs
Term
What are common side effects of Toradol?
Definition
Bleeding, GI upset, Renal dysfxn (NSAID rxns), Anemia, edema, HTN, tinnitus, increased LFT's
Term
What is the black box warning associated with Toradol?
Definition
GI bleed risk, Cardiovascular (MI, stroke) risk and renal risk
Term
What is the brand name for Morphine
Definition
Morphine
Term
What is the indication for morphine?
Definition
Pain
Term
How is Morphine supplied?
Definition
10mg/0.7ml autoinjector
Term
How is Morphine dosed?
Definition
10mg injection, may repeate in 30min if needed
Term
What are some drug interactions associated with Morphine?
Definition
CNS depressants, analgesics, anesthetics, phenothiazines, tricyclic antidepressants, tranquelizers, alcohol
Term
What are the side effects of Morphine?
Definition
Sedation, respiratory depression, shock and cardiac arrest
Term
What is the brand name for Meperidine?
Definition
Demerol
Term
What is the generic name for Demerol?
Definition
Meperidine
Term
What is the indication for Demerol/Meperidine?
Definition
Moderate to severe pain
Term
How is Demerol/Meperidine supplied?
Definition
50mg and 100mg tablets
Term
How is Demerol/Meperidine normally dosed?
Definition
50 to 100mg by mouth every 3-4 hours as needed
Term
What is a contraindication of Demerol?
Definition
MAOI (monoamine oxidase inhibitors) hypersensitivity
Term
What are some warnings associated with Demerol/Meperidine?
Definition
drug abuse problems, alcohol, head injury (Increased CSF pressure), asthma/respiratory conditions, hypotension and pregnancy
Term
What drug interactions are associated with Demerol?
Definition
Acyclovir, Ritonavir, Opiods, phenytoin and Cimetidine
Term
What are the side effects of Demerol?
Definition
Respiratory depression, sedation, cardiac arrest, shock
Term
What is the black box warning associated with Demerol?
Definition
Habit forming
Term
What is the brand name for Hydromorphone?
Definition
Dilaudid
Term
What is the generic name for Dilaudid?
Definition
Hydromorphone
Term
What is the indication for Dilaudid/hydromorphone?
Definition
Moderate to severe pain for patients requiring higher than normal doses of opiods
Term
How is Dilaudid/hydromorphone supplied?
Definition
1, 2 and 4mg/ml as 1ml ampule for IV/IM/SQ injection also as 10mg/ml and 250mg/25ml (Same concentration) powder for reconsitution
Term
What is the dosing for Dilaudid/hydromorphone?
Definition
1-2mg injection over 3 minutes
Term
what are the contraindications for Dilaudid?
Definition
respiratory depression, patient NOT already on high dose of opiods, obstetrics
Term
What are some drug interactions associated with Dilaudid?
Definition
Sedatives, hypnotics, anesthesia, tranquilizers, alcohol, pentazocine, nalbuphine, butorphanol, buprenophine
Term
What are some side effects of Dilaudid?
Definition
Lightheaded/dizzy, sweating, dry mouth, N/V, euphoria, dysphoria, puritis, flushing
Term
What is the black box warning associated with Dilaudid?
Definition
Death due to respiratory depression
Term
What is the brand name for Fentanyl Citrate?
Definition
Duragesic
Term
What is the generic name for Duragesic?
Definition
Fentanyl Citrate
Term
What is the indication for Fenatanyl?
Definition
persistent moderate to severe pain with need for "around the clock opioid use"
Term
How is Duragesic supplied?
Definition
12, 25, 50, 75 and 100mcg/hr transdermal patches
Term
What is the normal dose for Fentanyl?
Definition
apply one patch and leave on for 72 hours, apply new patch to a different site
Term
What are some contraindications for Duragesic?
Definition
Non-opioid tolerant patients and acute forms of pain (can be better managed with PO)
Term
What are some warnings associated with Duragesic?
Definition
No heat around patch, respiratory depression and only for opioed resistant patients
Term
What are side effects of Fentanyl?
Definition
N/V/C, Dizzy, drymouth, urinary retention, anxiety, depression, halucination, euphoria, tremor, flu like sx, hypo/hypertension, hypoventiliation
Term
What is the brand name for Moxiifloxacin opthalmic solution?
Definition
Vigamox
Term
What is the indication for Vigamox/moxyfloxacin?
Definition
Bacterial conjunctivitis
Term
How is Vigamox/moxyfloxacin supplied?
Definition
0.5% (5mg/ml) ophthalmic solution
Term
How is Vigamox/moxyfloxacin dosed?
Definition
1 drop in affected eye TID for 7 days
Term
What is a contraindication of Viagmox/moxyfloxacin?
Definition
Quinolone hypersensitivity
Term
What are the side effects of Vigamox/Moxyfloxacin?
Definition
Decreased visual acutity, dry eyes, keratitis, hyperemia, otitis media, fever, pharyngitis, rhinitus
Term
What is the brand name for Bimatoprost?
Definition
Lumigan
Term
How is Lumigan/Bimatoprost supplied?
Definition
0.1mg/ml (1%) and 0.3mg/ml (3%) ophthalmic solution
Term
What is the typical dosing of Lumigan/bimatoprost?
Definition
1 drop in affected eye every evening
Term
What are some side effects of Lumigan/Bimatoprost?
Definition
Eyelash growth, ocular puritis, hyperemia (increased blood flow)
Term
What is the brand name of Tobramycin with Dexamethasone (ophthalmic)
Definition
Tobradex
Term
What is the generic name for Tobradex?
Definition
Tobramycin and Dexamethasone
Term
What is the indication for Tobradex?
Definition
Bacterial conjunctivitis
Term
How is Tobradex supplied?
Definition
0.3%-0.1% (Tob-Dex) Ophthalmic suspension in 2.5, 5, and 10ml bottles
Term
What is the normal dosing for Tobradex?
Definition
1-2 drops in affected eye every 4-6 hours
Term
What contraindiactions does Tobradex have?
Definition
Fungal infection, mycobacterial infection, vaicella, viral infection
Term
What are the side effects of Tobradex?
Definition
Itching eyes (puritis), swelling, conjunctival erythema
Term
What is the brand name for Travoprost?
Definition
Travatan
Term
What is the generic name for Travatan?
Definition
Travoprost
Term
What is the indication for Travatan?
Definition
Open-angle glaucoma (aka chronic), Ocular hypertension
Term
How is Travatan supplied?
Definition
0.04mg/ml (0.4%) ophthalmic solution
Term
Which is a suspension rather than solution? Travatan, Lumigan, Tobradex or Vigamox?
Definition
Tobradex is a suspension
Term
What is the typical dosing for Travatan?
Definition
1 drop in affected eye each evening
Term
What side effect is associated with Travatan?
Definition
Conjunctival hyperemia (increased blood flow)
Term
What is the brand name for Acetazolamide?
Definition
Diamox
Term
What is the generic name for Diamox?
Definition
Acetazoldamide
Term
What is Diamox indicated for?
Definition
Edema, Glaucoma and Seizures
Term
How is Diamox supplied?
Definition
500mg/5ml powder for reconstitution IV
Term
What is the normal dose for Diamox?
Definition
250-375mg qd for 2 days then allow a medication free day
Term
What are some side effects of Diamox?
Definition
Paresthesias (tingling), tinnitus, taste alteration/decreased appetite, GI upset
Term
What is the brand name for Silver Sulfadiazine?
Definition
SSD
Term
What is the generic name for SSD?
Definition
Silver Sulfadiazine
Term
What is SSD indicated for?
Definition
Use as an antimicrobial in 2nd and 3rd degree burns
Term
What is SSD indicated for?
Definition
Use as an antimicrobial in 2nd and 3rd degree burns
Term
How is SSD supplied?
Definition
1% topical cream
Term
What is the normal dosing for SSD?
Definition
Apply to affected area one to twice daily
Term
What contraindications does SSD have?
Definition
Pregnant women almost to term and infants/newborns
Term
What are the side effects of SSD?
Definition
Leucopenia, pain, burning, itching
Term
What is the brand name for Collagenase?
Definition
Stantyl
Term
What is the generic name for Stantyl?
Definition
Collagenase
Term
What is Stantyl/Collagenase indicated for?
Definition
Chronic skin ulcers or severe burns. It is a debriding agent
Term
How is Stantyl/Collagenase supplied?
Definition
250u/gm in 15 and 30gm tubes (topical)
Term
What is the normal dosing of Stantyl/Collagenase?
Definition
Apply to affected area once daily
Term
What are some side effects associated with Stantyl?
Definition
Erythema, systemic bacterial infections (in debilitate patients)
Term
What is the brand name for Diflorasone Diacetate?
Definition
Psorcon E
Term
What is the generic name for Psorcon E?
Definition
Diflorasone Diacetate
Term
What is the indication of Psorcon/Diflorsone?
Definition
itchy and inflamed dermatitis (including psoriasis)
Term
How is PsorconE/Diflorasone supplied?
Definition
0.5mg/gm topical ointment in 15, 30 and 60gm
Term
What is the normal dosing of PsorconE/Diflorasone?
Definition
Apply to affected area once to four times daily
Term
What are some side effects of PsorconE/Diflorasone?
Definition
Burning, itching, foliculitus, hypertrichosis (hair growth), acene, hyperpigmentation, Perioral dermiatits, striae, skin atrophy, maceration (skin over moistened turns white)
Term
What is the brand name for Ciprofloxacin and Dexamethasone?
Definition
Ciprodex
Term
What is the generic name for CiproDex?
Definition
Ciprofoxacin and Dexamethasone
Term
What is CiproDex indicated for?
Definition
Otitis media and otitis externa caused by Staph, strep and pseudomonas bacteria
Term
How is CiproDex supplied?
Definition
0.3%-0.1% (Cipro-Dex) otic suspension
Term
How is CiproDex dosed?
Definition
4 drops in affected ear twice daily for 7 days
Term
What are the contraindications of CiproDex?
Definition
Quinolone hypersensitivity, viral ear infections (herpes)
Term
What are the side effects of CiproDex?
Definition
Ear pain, ear precipitate, irritablity, rash, congestion
Term
What medication would you use to treat ear infection? CiproDex, Vigamox, TobraDex or Lumigan?
Definition
CiproDex
Term
What drugs are indicated for Glaucoma? How are they dosed
Definition
Lumigan and Travatan. 1 drop in affected eye every evening
Term
Which two drugs are available as 60mg/2ml?
Definition
Toradol (IM) and Norflex
Term
What drugs can be used for preop and preanasthesia pain?
Definition
Stadol and Nubian
Term
Which cause hyperemia?
Definition
lumigan, vigamox and travatan
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