Term
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Definition
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Term
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Definition
| An example of a very large drug MW 59,050 |
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Term
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Definition
| A chiral drug- S enantiomer has higher affinity than R |
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Term
| Warfarin- physical properties |
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Definition
| Sold as a racemic mixture- S more potent than R |
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Term
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Definition
| A drug that binds to structural protein- binds to Tubulin and inhibits mitosis |
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Term
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Definition
| Chemical antagonist- binds to heparin |
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Term
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Definition
| Osmotic Agent- for subarachnoid hemmorhage |
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Term
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Definition
Blocks Beta-adrenergic receptor of heart myocardium- reduces contractile force
(Anti-hypertensive) |
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Term
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Definition
| Muscarinic blocker- mydriasis, GI disorders, organophosphate poisoning, supress respiratory secretions |
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Term
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Definition
| Muscarinic blocker- amnesia and sedation, prevent motion sickness |
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Term
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Definition
| Muscarinic blocker- treatment of asthma |
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Term
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Definition
| Ganglionic blocker- short-term treatment of hypertension |
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Term
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Definition
| Ganglionic blocker- treatment of moderately severe to severe hypertension |
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Term
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Definition
An example of a drug that is metabolyzed differently by slow vs. fast acetylators
-anti-TB |
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Term
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Definition
| An example of a weak acid- both neutral and aq forms co-exist in solution |
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Term
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Definition
| An example of a weak base- antimalarial |
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Term
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Definition
| An example of a weak acid- mostly neutral in stomach so absorbed |
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Term
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Definition
| An example of a sublingual drug- fast relief and lipid soluble |
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Term
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Definition
| An example of an anesthetic gas |
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Term
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Definition
| An example of an anesthetic gas |
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Term
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Definition
| An example of drugs that are lipid-soluble and accumulate in fat tissues |
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Term
| Salicylates, warfarin, amipicillin, levodopa |
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Definition
| Examples of acidic drugs that bind to albumin |
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Term
| Allopurinol, chloroquine, fluphenazine |
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Definition
| Examples of basic drugs that bind to glycoproteins |
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Term
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Definition
| An example of a lipid-soluble drug that crosses the Blood Brain Barrier |
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Term
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Definition
| Examples of fat soluble drugs that store in adipose tissue |
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Term
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Definition
| An example of a prodrug whose metabolism can be subject to polymorphisms of CYP2D6 |
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Term
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Definition
| Inducer of CYP1A2- induces Acetaminophen, Tamoxifen |
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Term
| Barbiturates (eg- Nembutal) |
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Definition
| Inducer of CYP2C9- induce Celecoxib, Losartan |
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Term
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Definition
| Inducer of CYP3A4- induce Diazepam, Spironolactone |
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Term
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Definition
| Inducer of CYP3A4- induces Diazepam, Spironolactone |
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Term
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Definition
| Inhibitor of CYP1A2- inhibits Acetaminophen, Tamoxifen |
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Term
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Definition
| Inhibitor of CYP2D6- inhibits Codeine, Metoprolol |
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Term
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Definition
| Inhibitor of CYP3A4- inhibits Diazepam, Spironolactone |
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Term
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Definition
| Inhibitor of CYP3A4- inhibits Diazepam, Spironolactone |
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Term
| Acetaminophen (Phase II Rxn-Alternative) |
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Definition
| An example of a drug that conjugates with Glutathione (GST-cytosol) |
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Term
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Definition
| An example of a drug that conjugates with Glycine (Acyl-CoA glycinetransferase- mitochondrion) |
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Term
| Acetaminophen (Phase II Rxn- Primary) |
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Definition
| An example of a drug that conjugates with Sulfation (SULTs-cytosol) |
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Term
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Definition
| An example of a drug that conjugates with methylation (TMTs-cytosol) |
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Term
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Definition
| An example of a drug that is eliminated via Zero-order Kinetics |
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Term
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Definition
| An example of a drug that is eliminated via Zero-order Kinetics |
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Term
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Definition
| An example of a drug that is eliminated via Zero-order Kinetics |
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Term
| Digoxin (re: target concentration) |
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Definition
| An example of a drug that has 2 uses at 2 different doses- lower dose for heart failure, higher dose for Afib |
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Term
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Definition
| An example of a drug with a long half-life that requires the use of a loading dose (bolus) |
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Term
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Definition
| An example of an autacoid drug- works on 5HT1 receptor |
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Term
| Spironolactone (receptor action) |
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Definition
| An example of a hormone receptor drug- works on NR3C2 receptor |
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Term
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Definition
| An example of a drug that binds to a neurotransmitter receptor- Alpha1 |
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Term
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Definition
| A drug that binds to acetylcholinesterase (Binds to enzyme) |
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Term
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Definition
| A drug that binds to Vitamin K epoxide reductase (Binds to enzyme) |
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Term
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Definition
| A drug that binds to Reverse Transcriptase (binds to enzyme) |
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Term
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Definition
| A drug that binds to Ca2+ channels |
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Term
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Definition
| An example of a full agonist- binds to M receptor |
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Term
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Definition
| An example of a partial agonist- binds to Beta receptor |
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Term
| Scopalamine (drug-receptor interaction_ |
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Definition
| An example of a competitive antagonist |
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Term
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Definition
| An example of a non-competetive agonist (for Theochromocytoma) |
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Term
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Definition
| An example of an allosteric antagonist |
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Term
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Definition
| An example of an inverse agonist |
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Term
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Definition
| An example of physiological antagonism |
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Term
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Definition
| An example of a non-receptor drug- coats ulcers in stomach |
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Term
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Definition
| An example of a partial agonist- produces opposite effects in normal versus hypertensive patients with elevated angiotensin II |
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