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DNA
UC MED 2015
20
Medical
Graduate
10/06/2011

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Cards

Term
The the C-1' of pentose is linked to the base through
Definition
a glycosidic linkage
Term
The C-5' of pentose is linked to the
Definition
phosphate through a phosphoester linkage
Term
is a sugar linked to a base with NO phosphate attachment
Definition
nucleoside
Term
the difference between ribose and deoxyribose is
Definition
2' -OH
Term
individual nucleotides are linked together through
Definition
a phosphodiester linkage a 5' to 3' linkage
Term
Chargaff's Rule states that
Definition
A=T and G=C and add it all together to get 100%
Term
number of hydrogen bonds between G-C
Definition
3
Term
number of h-bonds between A-T
Definition
2
Term
ds DNA has a(n)__________ orientation
Definition
anti-parallel
Term
ds DNA is a right/left handed helix that has________bp per turn
Definition
right and 10
Term
when synthesizing DNA or mRNA the strand is read in the___________direction
Definition
3' to 5'
Term
base pairs are ___________ to the helix
Definition
perpendicular
Term
What is a distinctive characteristic of HIV/AIDS medications that block anti-retroviral reproduction.
Definition
Add dideoxynucleosides....ones that lack both a 2' and a 3' -OH group
Term
how many different purine and pyrimidine compounds are required precursors of nucleic acids
Definition
5
Term
the paired chains of DNA have __________ polarity
Definition
opposite
Term
DNA is more stable than RNA
Definition
because its double stranded, and 2' -OH makes it more susceptible to hydrolysis
Term
Does DNA pol III require a sigma subunit?
Definition
No only RNA polymerase in prok.
Term
RNA primers are synthesized by
Definition
DNA primase
Term
What is the minimum set of bacterial proteins needed for DNA synthese
Definition
DNA pol III, primase, helicase, and SSB
Term
short strand of DNA found on the lagging strand in both prok. and euk.
Definition
Okazaki fragments
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