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DNA structure and function
dna
22
Biology
Undergraduate 1
11/28/2007

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Term
DNA
Definition

the storehouse of information that governs heritable traits. Its found on the nucleus of eukaryotic cells.

 

a double stranded molecule consisting of four kinds of nucleotides: adenine, thymine, guanine, and cytosine.

 

Its strands are in opposite directions; the strands are complimentary not exact.

 

the two strands coil together helically, like a spiral stairway.

Term
Johann Miescher
Definition
1868, discovered what came to be known as DNA.
Term
Frederick Griffith
Definition
discovered DNA transformation;
Term
Bacteriophages
Definition
one of a class of viruses that infects bacteria.
Term
Watson and Crick
Definition

discovered the dna double helix;

 

the apperance of dna in all cells;

Term
Adenine and Guanine
Definition
purines; larger and bulkier molecules having two rings.
Term
Thymine and Cytosine
Definition
pyrimidines, with a backbone of carbon and nitrogen that forms a single ring.
Term
Erwin Chargaff
Definition

resposnible for these two ensights:

 

the amount of adenine and guanine differs amoung species.

 

The amounts of thymine and adenine in DNA are identical and so are the amounts of cytosine and guanine. A=t and G=C.

Term

X-Ray diffraction images

Definition

made by Rosalind Franklin (first to put DNA in a "wet" form);

 

a beam of x-rays is directed at a molecule, which scatters the x-rays in a pattern that can be captured on film.

Term
Function of DNA
Definition

Storage of info

 

replication - dna makes exact compies of itself

 

mutation - change in DNA sequence

 

transformation - DNA moves from one cell to the next in bacteria cell.

Term
nucleic acid
Definition
composed of nucleotides (simple building units);
Term
nucleotides
Definition

simple building units of nucleic acid;

 

composed of three parts:

 

sugar:deoxiribose

Phosphate group

Nitrogen base

Term

Two types of nitrogen bases

Definition

purines:adenine and guanine

 

pyrimidines: cytosine and thymine

Term
Stahl
Definition

discovered the semi-conservative replication of DNA;

 

each DNA molecule is comosed of an old and new strand;

Term
Replication
Definition

 

DNA makes an exact copy of itself;

 

replicatiion will always occur before cell reproduction;

 

replcation occurs in the nucleus of eukaryotic cells (which is where DNA is located).

Term
Chargaff
Definition
discovered complementary pattern between DNA strands;
Term
DNA Helicase
Definition

First enzymes present in replication;

 

unravel DNA double helix;

Term
DNA polymerse
Definition

2nd enzymes present in replication;

 

add free complimentary nucleotides to each DNA strand;

 

monomers of DNA

Term
DNA Ligase
Definition

last enzyme of replication;

 

seals dna fragments;

Term
DNA proofreading mechanisms
Definition
swiftly fix most errors in replication and most of the strand breaks;
Term
Repair enzymes
Definition

recognize and snip out a damage site or mismatches;

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