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DNA Replication
for the week of october 12th
40
Biology
9th Grade
10/15/2009

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Term
polypeptide chains
Definition
made up of long chains of amino acid
Term
Griffith
Definition
Discovered that DNA was genetic material
Term
Transformation
Definition
The process of picking up DNA from the environment
Term
Chargaff's Rule
Definition
The amount of Guanine equals the amount of Cytosine, and the amount of Adenine equals the amount of thymine
Term
hydrogen bonds
Definition
weak bonds that join the base pairs of DNA
Term
Rosalind Franklin
Definition
discovered that DNA is a double helix
Term
Watson and Crick
Definition
built the first model DNA using Chargaff's and Franklin's data. Also developed the idea of semi-conservative replication
Term
Nucleotides
Definition
subunits that make up DNA
Term
purines
Definition
double ringed nitrogen base
Term
pyrimidines
Definition
single ring nitrogen bases
Term
adenine, guanine
Definition
name the purines
Term
thymine, cytosine
Definition
name the pyrimidines
Term
three
Definition
____ hydrogen bonds are required to join guanine and cytosine
Term
two
Definition
two____ hydrogen bonds are required to to join adenine and thymine
Term
origins of replication
Definition
replication begins at this point
Term
Forks
Definition
where DNA strands grow
Term
Helicase
Definition
Enzyme that uncoils the DNA
Term
RNA Primer
Definition
must be present to start the addition of new nucleotides
Term
Primase
Definition
makes RNA primer
Term
DNA Polymerase
Definition
catalyzes the addition of appropriate nucleotides to the new DNA strand
Term
leading strand
Definition
DNA strand that is continuously synthesized as a single strand
Term
lagging strand
Definition
DNA strand the is continuously synthesized against the overall direction of replication
Term
Okazaki Fragments
Definition
the short segments of the lagging strand
Term
Ligase
Definition
joins Okazaki Fragments into one strand
Term
Semi-Conservative replication
Definition
Two strands of parental molecule separate, each acts as a template for a new complementary strand
Term
excision repair
Definition
occurs when any of the repair enzymes remove damaged parts of the DNA
Term
It contains the sugar ribose and uracil replaces Thymine, and its single stranded
Definition
RNA is different from DNA because
Term
Ribosobial, messenger, transfer
Definition
Three types of RNA
Term
Transcription
Definition
the synthesis of mRNA from DNA, mRNA then takes genetic info into the cytoplasm to begin protein synthesis
Term
Messenger RNA (mRNA)
Definition
travel from the nucleus to the ribosome to direct the synthesis of a certain protein
Term
Ribosomal RNA
Definition
RNA that associates with proteins to form ribosomes in the cytoplasm
Term
transfer RNA
Definition
smaller segments of RNA nucleotides that transfer amino acids to the ribosome. In translation thy act as interpreters of the mRNA codon sequence
Term
RNA Polymerase
Definition
an enzyme that regulates RNA synthesis, initiates mRNA synthesis
Term
codon
Definition
the three base code in DNA and mRNA
Term
Translation
Definition
when a code in the mRNA is read by the tRNA and translated to make a polypeptide
Term
George Beadle, Edward Tatum
Definition
provided evidence that a gene can code for an enzyme by studying mold spores
Term
RNA Polymerase
Definition
enzyme that regulates RNA synthesis
Term
Codon
Definition
the three base code in DNA and RNA
Term
Translation
Definition
once the 5' side of the mRNA attaches to the ribosome, this is where the code is read and translated to make a protein. Occurs is the cytoplasm in prokaryotes
Term
Anti-Codon
Definition
is complimentary to the codon in mRNA. is read 3' to 5' which is the opposite
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