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DIURETICS-BY H.K.M
DIURETICS
5
Pharmacology
12/22/2009
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Term
DIURETICS
 Definition
DRUGS WHICH CAUSE NET LOSS OF SODIUM AND WATER IN URINE
Term
CLASSIFICATION
 Definition

1.HIGH EFFICACY DIURETICS

2.MEDIUM EFFICACY DIURETICS

3.WEAK OR ADJUNCTIVE DIURETICS
Term

HIGH EFFICACY DIURETICS/INHIBITORS OF Na+-K+-2Cl-

CO TRANSPORT

 Definition

SULPHAMOYL DERIVATIVES

FUROSEMIDE

BUMETANIDE

TORASEMIDE
Term

MEDIUM EFFICACY DIURETICS/INHIBITIORS OF

Na+Cl-  SYMPORT

 Definition

a)BENZOTHIADIAZINES(THIAZIDES)

 

HYDRO CHLORO THIAZIDE,BENZTHIAZIDE,

 

HYDROFLUMETHIAZIDE,CLOPAMIDE

 

b)THIAZIDE LIKE(RELATED HETROCYCLICS)

 

CHLORTHALIDONE,METOLAZONE,XIPAMIDE,

 

INDAPAMIDE
Term
WEAK OR ADJUNCTIVE DIURETICS
 Definition

A)CARBONIC ANHYDRASE INHIBITORS-acetazolamidE

 

 

B)POTASSIUM SPARING DIURETICS

1.aldosterone antagonists:spironolactone

2.inhibitors of renal epithelial Na+ channel:triamterene,amiloride

C)OSMOTIC DIURETICS

mannitol,isosorbide, glycerol