Term
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Definition
| study of disease states over or under reactivity of the immune response |
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Term
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Definition
| alters or exaggerates immune response |
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Term
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Definition
| delayed reactions to an allergy |
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Term
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Definition
IgE antibody--B cells from IgE (sensitizing dose)
Provocative dose--subsequent exposure binds allergen to IgE creating mast cell complex--degranulation
Hypersensitivity reaction, response to an allergen |
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Term
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Definition
| any chronic local allergy such as hay fever or asthma (type I hypersensitivity) |
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Term
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Definition
| a systemic often explosive reaction that involves airway obstruction and circulatory collapse |
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Term
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Definition
Reactions that lyse foreign cells
--involve transfusion reactions: ABO blood groups, Rh factor, HDN |
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Term
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Definition
A, B, AB, O
a) blood type named for dominant antigen
b) Type O persons LACK A and B antigens
[image] |
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Term
| Type III hypersensitivity |
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Definition
A large quantity of soluble foreign antigen stimulates antibiodies that produce small, soluble antibody-antigen complexes
---immune complexes become trapped in tissues and incite a damaging inflammatory response |
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Term
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Definition
| a local reaction to a series of injected Ag to same body site |
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Term
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Definition
| systemic disease resulting from repeated injections of foreign proteins |
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Term
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Definition
T cell mediated, delayed response to Ag involving activation and damage by T cells
1. Delayed allergic response-PPD, poison ivy, contact dermatitis
2. Graft rejection-reaction of cytotoxic cells directed against foreign cells of a grafted tissue |
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Term
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Definition
| recipient also serves as donor |
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Term
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Definition
| tissue from identical twin is grafted |
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Term
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Definition
| genetically different individuals but in the same species (human to human) |
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Term
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Definition
| individuals from different species are host and recipient (valve from a pig heart going to a human) |
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Term
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Definition
systemic lupus
rhumatoïde arthritis |
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Term
| Autoimmunity of the endocrine gland |
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Definition
Graves disease
Hashimoto's thyroiditis
Diabetes mellitus |
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Term
| Neuromuscular autoimmunities |
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Definition
Myasthenia gravis
Multiple sclerosis |
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Term
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Definition
components of the immune system are missing
B and T cells, phagocytes are not there |
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Term
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Definition
lack of B or T cell activity, T cell defect--thymus is missing or abnormal
congenital, usually genetic errors
SCID (severe combined immunodeficiency--no immune response |
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Term
| secondary immunodeficiency |
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Definition
acquired after birth, caused by natural or artificial agents
caused by infection, disease, chemotherapy or radiation
AIDS--T helper cells are targeted |
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