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Disease Detectives B 2016
Science olympiad 2016 B
18
Biology
Not Applicable
02/22/2016

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Term





Cluster

Definition
An aggregation of cases over a particular period closely grouped in time and space, regardless of whether the number is more than the expected number
Term
Outbreak
Definition
More cases of a particular disease than expected in a given area or among a specialized group of people over a particular period of time.
Term
Epidemic
Definition
Large numbers of people over a wide geographical area are affected
Term
Pandemic
Definition
An epidemic occurring over several countries or continents and affecting a large proportion of the population.
Term
Surveillance -
Definition
The systematic and ongoing collection, analysis, interpretation, and dissemination of health data. The purpose of public health surveillance is to gain knowledge of the patterns of disease, injury, and other health problems in a community so that we can work towards their prevention and control.
Term
Plague
Definition
A serious, potentially life-threatening infectious disease that is usually transmitted to humans by the bites of rodent fleas. It was one of the scourges of our early history. There are three major forms of the disease: bubonic, septicemic, and pneumonic.
Term
Vector
Definition
An animal that transmits disease. For example a mosquito is a vector for malaria.
Term
Fomite
Definition
A physical object that serves to transmit an infectious agent from person to person.
Term
Risk
Definition
The probability that an individual will be affected by, or die from, an illness or injury within a stated time or age span. Risk of illness is generally considered to be the same as the Incidence (see below) and the terms are used interchangeably. Age-span is not usually a consideration in this usage. Risk of death from a particular illness is expressed as the Case Fatality Rate (Number deaths due to a disease/Number with the disease) or the Cause-specific Mortality Rate (Number deaths due to a disease/Number in population). Age span is a more common consideration in this last usage.
Term
Zoonosis
Definition
An infectious disease that is transmissible from animals to humans.
Term
Incubation Period
Definition
Time in between when a person somes into contact with a pathogen and when they first show symptoms or signs of disease.
Term
Endemic Disease
Definition
Present at a continuous level throughout a population/geographic area; constant presence of an agent/health condition within a given geographic area/population; refers to the usual prevalence of an agent/condition.
Term
The INCIDENCE of an illness
Definition
The INCIDENCE of an illness is the number of new instances of disease in a population over a given time period. It is expressed as "X cases/Y population/ Z time"
Term
The PREVALENCE of an illness is
Definition
The PREVALENCE of an illness is number of affected persons in the population at any given point in time. It is expressed as "X cases/Y population". Note the only difference is that INCIDENCE (I) includes time while PREVALENCE (P) does not
Term
Hill's Criteria for Causation
Definition
Nine criteria must be met to establish a cause-and-effect relationship. This is commonly known as Hill's Criteria for Causation:
Term
Hill's Criteria for Causation
Definition
Strength of Association - relationship is clear and risk estimate is high
Consistency - observation of association must be repeatable in different populations at different times
Specificity - a single cause produces a specific effect
Alternative Explanations - consideration of multiple hypotheses before making conclusions about whether an association is causal or not
Temporality - cause/exposure must precede the effect/outcome
Dose-Response Relationship - an increasing amount of exposure increases the risk
Biological Plausibility - the association agrees with currently accepted understanding of biological and pathological processes
Experimental Evidence - the condition can be altered, either prevented or accelerated, by an appropriate experimental process
Coherence - the association should be compatible with existing theory and knowledge, including knowledge of past cases and epidemiological studies
Term
Chain of Transmission Triad
Definition
An external agent
A vector or fomite that transmits the disease
A susceptible host for the disease
This is used to define the major points of a disease case.
Term
Epidemiological Study Designs
Definition
Ecological - comparisons of geographical locations

Cross Sectional - a survey,health questionnaire, "snapshot in time"

Case-Control - compare people with and without disease to find common exposures

Cohort - compare people with and without exposures to see what happens to each

Randomized Controlled Trial - human experiment

Quasi Experiments - research similarities with traditional experimental design or RCT, but lack element of random assignment to treatment/control
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