• HCL: lowers pH of gastric contents
• Intrinsic factor: promotes absorption of vitamin B₁₂
• B₁₂ deficiency causes pernicious anemia.

They look like fried eggs(sunny side up)

They are pink(acidophilic)

Located in the mucosa(Fundus and Body)

• Cardia
• Fundus
• Body
• Pylorus

• Located at the base of the mucosa in the Fundus and Body of stomach.

Function:

-secrete Pepsinogen which is activated by low pH to become the protease Pepsin.

-secrete Gastric Lipase which has weak lipolytic activity.(weak break down of some fat)

They are basophilic and appear blue.

Located around parietal cells (Fundus and Body)

They secrete mucous that ends up being acidic because of the H+ that the parietal cells are releasing.

Cardiac of the Stomach

• Shallow Pits
• Mucous glands
• few if any parietal and cheif cells

Fundus and Body of Stomach

• Very shallow ridges
• Two toned because of Parietal and Chief cells.

Gastroduodenal Junction

• Thickening of Inner circular layer of muscularis externa to form Pyloric Phincter.
• Can see the villi of the small intestine

Gastroesophageal Junction

• Distiction between stratified sqamous to simple cuboidal.

Pylorus of Stomach

• Deep pits
• Mucous glands
• few if any parietal or cheif cells.