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DHM - bone, cartilage, & soft-tissue tumors
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17
Aerospace Engineering
2nd Grade
03/23/2012

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Cards

Term
Metaphysis of long bones in kids (<20)
grows out like a stalk
may progress to ___
Definition
osteochondroma ("extosis")

may progress to chondrosarcoma
Term
in medullary cavity of bones of distal extremities
Definition
enchondroma
Term
many enchondromas

many enchondromas + telangiectasia
Definition
Enchondromatosis (Ollier disease)

Maffucci syndrome (increased risk of ovarian & brain tumors)
Term
glistening, malignant mass in medullary cavity. Derived from enchondroma or osteochondroma
Definition
chondrosarcoma
Term
benign osteoblastic tumor <2cm
'' >2cm
Definition
osteoid osteoma
osteoblastoma
Term
things associated w/ gardner syndrome
Definition
- APC mutation
- Desmoid tumors (deep, intrabdominal fibromatosis)
- Osteomas (esp on jaw)
- epidermoid cysts
- sebaceous cysts
Term
Osteosarcoma most likely patient
Definition
male <20 (second smaller peak in elderly)
Term
osteosarcoma risks?
typical locations?
Definition
male, pagets, avascular necrosis, irradiation, RB, p53

Knee>hip>shoulder>jaw
Term
Codman's triangle
Definition
osteosarcoma raises periosteum
Term
soap-bubble on radiography
Definition
giant cell tumor (from lysis, expresses RANK-L)
Term
homer-write pseudorossettes
Definition
ewing sarcoma
Term
translocation in ewing sarcoma
Definition
t (11;22) (EWS gene)
Term
4% met to lungs
Definition
malignant giant cell tumor
Term
factor XIII positive
Definition
fibrous histiocytoma (aka dermatofibroma)
Term
pax3-fkhr fusion
Definition
rhabdomyosarcoma
Term
t(x;18) SYT-SSX fusion
Definition
synovial sarcoma
Term
biphasic differentiation
Definition
synovial sarcoma
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