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Dermatology
Patho Final
36
Pathology
Post-Graduate
10/28/2012

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Cards

Term
Epidermis
Definition
outermost layer of skin
5 layers:
basal cell layer
stratum spinosum
stratum granulosum
stratum lucidum
stratum corneum
Term
Dermis
Definition
middle layer of skin
Term
Sub-cutaneous
Definition
deepest layer of skin
brown fat:
protects, insulates, source of energy
Term
Primary lesion
Definition
a lesion that has not been altered by trauma, manipulation or natural regression over time
Term
Secondary lesion
Definition
created because of scratching, scrubbing, manipulation, or infection
may develop naturally with time
Term
Carbuncle
Definition
deep staph skin infection
painful, erythematous, papule, pustule, or nodule that grows rapidly
Term
Cyst
Definition
deeper and bigger than carbuncle
usually no treatment necessary
Term
Dermatitis
(contact)
Definition
characterized by puritis or burning of the skin
caused by external agents
Term
Dermatitis
(atopic/eczyma)
Definition
family history of hay fever, asthma, allergic rhinitis
itchy and dry skin
**never take a hot bath (increases puritis)
**presents on flexor surface
Term
Dermatitis
(Seborrheic/dandruff)
Definition
redness and scaling
occurs in area of skin where sebacceous glands are most active
Term
Folliculitis
Definition
inflammation of hair follicles
characterized by erythema
Term
Herpes
Definition
caused by herpes virus I or II, or the varicella-zoster virus
Term
Hives/Urticaria
Definition
eruption of very pruritic wheals caused by an allergic reaction to a substance, food, or sudden changes in climate
Type I allergic reaction
Term
Pediculosis capitus
Definition
head lice
Tx: Kwell shampoo
Term
Pediculosis pubis
Definition
pubic lice
Term
Psoriasis
Definition
silver scaling patches and plaques
chronic, lifelong condition that may be controlled
**presents on extensor surfaces
Term
Scabies
Definition
highly communicable skin disease caused by a tiny mite
characterized by pruritis
commonly starts in web spaces
Term
Tinea
Definition
Ringworm
erythematous, pruritic superficial fungal infection that can present itself anywhere on the body
curable
Term
Tinea pedis
Definition
athlete's foot
erythematous, pruritic superficial fungal infection that can present itself anywhere on the body
Term
Tinea cruris
Definition
jock itch
erthematous, pruritic superficial fungal infection that can present itself anywhere on the body
Term
Verucca
Definition
warts
a benign skin infection caused by HPV
firm, hyperkeratotic, papule, can be tender or painful
Term
Hair disorders
Definition
alopecia areata
tinea capitis
seborrhoeic dermatitis
dandruff
pediculosis capitis (lice)
androgenetic alopecia (progressive balding)
Term
Pre-cancerous skin lesions
Definition
actinic keratosis
actinic cheilitis
Term
Skin cancer
Definition
basal cell carcinoma
squamous cell carcinoma
melanoma
Term
Actinic keratosis/cheilitis
Definition
red or brown, dry, rough, scaly lesions that are noted on habitually sun-exposed skin of adults
Term
The ONLY cause of actinic keratosis
Definition
sun exposure
Term
Basal cell carcinoma
Definition
most common type of skin cancer
rarely metastasizes
UV light is the number 1 cause
a persistent, non healing sore
reddish patch, or irritated area, sometimes it crusts
ROLLED BORDER
Term
Squamous cell carcinoma
Definition
second most common type of skin cancer
can metastasize
Etiology:
UV light
chronic ulcers
smoking
HPV
chronic immunosuppression
wart like growth that crusts and bleeds, persistent for weeks
rapidly growing lesion
Term
Deadliest of all skin cancers
Definition
melanoma
Term
Primary prognostic factor for melanoma
Definition
depth of lesion
Term
ABCD of melanoma
Definition
A - Asymmetery
B - Border (irregular)
C - Color (varies from one area to another)
D - Diameter (>6mm = cancer)
Term
Classification of MM
- Superficial
Definition
most common
grows laterally before vertically
*found more commonly on younger ppl
Term
Classification of MM
- Lentigo maligna
Definition
*found mostly on the elderly
occurs exclusively on sun damaged skin of the head and neck
Term
Classification of MM
- Acral lentiginous melanoma
Definition
spreads laterally before vertically
most common in african americans and asians
Term
Classification of MM
- Nodular melanoma
Definition
worst, most aggressive
usually invasive at the time it is first diagnosed
grows vertically from its inception
Term
Melanoma accounts for __% of skin cancers but __% of deaths
Definition
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