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CV Exam 1 Proteins and Genes
Proteins, Genes, and Compounds for CV Exam 1
18
Medical
Professional
09/22/2011

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Cards

Term
vWF, CD31
Definition
markers for ECs
Term
CRP
Definition
acute phase reactant, upregulated by cytokines, binds to and promotes microbial elimination, present with atherosclerotic infection
Term
antineutrophil cytoplasmic antibody (ANCA)
Definition
seen in vasculitis
Term
Antiproteinase 3/PR3 (c-ANCA)
Definition
seen in Wegener's Vasculitis, cytoplasmic
Term
Antimyeloperoxidase/MPO (p-ANCA)
Definition
seen in Churg-Strauss and polyangitis, perinuclear
Term
Endothelial-Derived Hyperpolarizing Factor (EDHF)
Definition
vasodilator
Term
COX
Definition
synthesizes prostaglandin/thromboxane
Term
ADH
Definition
decreased by increased MAP
Term
Renin
Definition
released from juxtaglomerular cells, converts angiotensinogen to angiotensin I
Term
Angiotensinogen
Definition
secreted by liver, inactive form
Term
ACE
Definition
converts angiotensin I to angiotensin II
Term
Atrial Natriuretic Peptide (NAP)
Definition
released from atrial granules in response to increase atrial stretch, causes decreased Na resorption and increased H2O excretion, causes vasodilation and increased capillary permeability, mediated by cGMP
Term
Angiotensin II
Definition
causes vasoconstriction/renal retention/aldosterone release from adrenal cortex/ADH release from posterior pituitary/cardiovascular hypertrophy/ increase blood volume/ increased TPR
Term
Na+/Cl- transporter ENCC1
Definition
in Distal Convoluted Tubule, inhibited by thiazide-like diuretics
Term
Na+K+2Cl- symporter
Definition
in Ascending Loop of Henle, inhibited by loop diuretics
Term
Na+ channel (ENaC)
Definition
in collecting duct, inhibited by K+ sparing diuretics
Term
AT1 (AII) receptor
Definition
found in vessels/heart/brain/kidney/adrenal glomerulus
Term
liver rhodanese
Definition
converts CN to thiocyanate
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