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CSU BMS 300 Walrond
Human Physiology Unit 4: Skeletal System
48
Physiology
Undergraduate 1
02/17/2013

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Term
What are the three types of cartilage?
Definition
Hyaline, elastic, and fibrocartilage.
Term
Where is hyaline cartilage found?
Definition
Articular surfaces of joints, costal cartilage that connect the ribs to the sternum, and the larynx, trachea.
Term
Describe hyaline cartilage.
Definition
Tough yet flexible.
Term
Describe elastic cartilage.
Definition
Springy and resilient.
Term
What is an example of elastic cartilage?
Definition
External ear.
Term
What are two attributes of fibrocartilage?
Definition
It is able to withstand compression and tension.
Term
Where is fibrocartilage found?
Definition
Intravertebral disks and minisci of the knee joint.
Term
What are five functions of bone?
Definition
Support, protect, permit movement, provide a mineral source (calcium and phosphate), hematopoiesis (blood cell production).
Term
What are the four classifications of bone?
Definition
Long bones are longer than they are wide, short bones are stumpy and often nearly cuboidal, flat bones are found in the skull, clavical, and rib cage, and irregular bones are the vertebrae, pelvic bones, and scapula.
Term
What are the three regions of long bones?
Definition
Diaphysis (shaft) and two end regions called the ephiphyses.
Term
Which epiphysis is closer to the body? Farther away?
Definition
Proximal epiphysis, distal epiphysis.
Term
What is the center of the diaphysis called?
Definition
Medullary cavity.
Term
What is the medullary cavity filled with?
Definition
Yellow marrow composed of fat.
Term
What are the cells that tear down bone?
Definition
Osteoclasts.
Term
What is a three-dimensional structure that forms a column of compact bone?
Definition
Osteon.
Term
What is secreted by osteocytes to form the extracellular matrix?
Definition
Collagen and hydroxyapatite.
Term
What provides excellent compression strength in bones?
Definition
Hydroxyapatite.
Term
What provides the resistance to shear forces in bone?
Definition
Collagen fiber layers.
Term
How is compact bone constructed?
Definition
From a series of cylindrical structures called osteons.
Term
How are osteons organized?
Definition
Concentric rings called lamellae.
Term
What is the open area that the osteon resides in?
Definition
Lacuna.
Term
What is another name for spongy bone?
Definition
Trabecullar bone.
Term
What is spongy bone composed of?
Definition
A series of struts called trabeculae.
Term
Where is red bone marrow located? What is its purpose?
Definition
In the spongy bone. It is the site of red and white blood cell production.
Term
What is hematopoiesis?
Definition
Red and white blood cell production.
Term
What covers the proximal and distal epiphyses?
Definition
Articular cartilage.
Term
Other than the proximal and distal ephiphyses, what surrounds bone?
Definition
Periosteum.
Term
What is periosteum composed of?
Definition
Connective tissue.
Term
What do Sharpey's fibers attach to?
Definition
They attach periosteum to the underlying bone.
Term
How much of the osteon is organic secreted material?
Definition
About 33%. Particularly collagen and proteoglycans.
Term
What provides for flexibility of bone and for tensile strength?
Definition
Collagen fibers.
Term
How much of the osteon is composed of hydroxyapatite? What is hydroxyapatite mostly composed of?
Definition
65%. Mostly calcium phosphate.
Term
What are the two general types of bone formation in development?
Definition
Intramembranous ossification and endochondral ossification.
Term
What type of bone formation forms flat bones?
Definition
Intramembranous ossification.
Term
What type of bone formation begins as a layer of connective tissue where osteoblasts settle and begin forming bone?
Definition
Intramembranous ossification.
Term
What bone has irregularly organized collagen fibers and forms first? What later replaces it?
Definition
Woven bone. Spongy bone.
Term
How does endochondral ossification begin?
Definition
From "bones" shaped from hyaline cartilage.
Term
What do long bones develop from?
Definition
Endochondrial ossification.
Term
What is the layer surrounding the cartilage "bone?"
Definition
Perichondrium.
Term
What lays down osteoid and forms a bone collar around the cartilage "bone?"
Definition
Osteoblasts.
Term
What does the peristeal bud contain?
Definition
Blood vessels, nerves, and additional osteoclasts and osteoblasts.
Term
What leads to the formation of spongy bone in the center of the cartilage "bone?"
Definition
Periosteal bud.
Term
At birth, what are the epiphyses made of?
Definition
Cartilage.
Term
What is epiphyseal plate closure?
Definition
When the epiphyseal plates become narrow and are eventually replaced by bone.
Term
How do bones become thicker?
Definition
Appositional growth.
Term
What is the difference in structure between an osteoid and an osteon?
Definition
The osteoid has the same structure as an osteon, but it is not mineralized.
Term
What is added to the collegen fibers of the osteoid that leads to the hardening of the bone?
Definition
Calcium phosphate crystals.
Term
What hormone activates the osteoclasts to break down bone to release Ca into the blood stream?
Definition
Parathyroid.
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