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CSIM 10
Virology
11
Medical
Undergraduate 2
03/29/2013

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Cards

Term
Describe the structure of a virus.
Definition
All viruses possess a capsid- a protein coat that surround the viral DNA or RNA. This can be a sphere or an icosohedron or helical in structure. Some viruses are surrounded additionally by a lipid envelope.
Term
How does the influenza virus attach to human cells?
Definition
Using the hemagglutinin spike.
Term
Which groups does the Baltimore classification separate viruses into?
Definition
1) Double stranded DNA
2) Single stranded DNA
3) Double stranded RNA
4) Single stranded RNA (positive sense)
5) Single stranded RNA (negative sense)
6) Single stranded RNA viruses which use reverse transcription during replication .
Term
How are viruses classified into families?
Definition
On the basis of nucleic acid sequence.
Term
How are viruses classified within families?
Definition
Based on serotypes and genotypes.
Term
How does maraviroc work?
Definition
Binds to CCR5 (an HIV cellular co-receptor).
Term
How does aciclovir work?
Definition
Inhibits the DNA polymerase of the herpes simplex virus.
Term
How do zidovudine and efavirenz work?
Definition
Inhibit the reverse transcriptase enzyme of HIV.
Term
How does raltegravir work?
Definition
Inhibits integration of HIV DNA into the host chromosome.
Term
How does lopinavir work?
Definition
HIV protease inhibitor.
Term
How do influenzavirus neuraminidase inhibitors work?
Definition
They prevent viral release from the cell.
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