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Critical Care Test IV
Neuro, Head Injury, ICP, SCIs, Thyroid, DI, SIADH
363
Nursing
Undergraduate 4
07/08/2011

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Term
Drug classes used for Excessive movemnt, sedation or with short-acting paralytics and pain control. (3)
Definition
Sedatives
Barbiturates
Hypnotics
Term
What do short-acting barbiturates c hypnotics & analgesics/lidocaine do?
Definition
Sedate
Blunt cough reflex
Term
10-15% of ICP patients are _____ to usual care.
Definition
Refractory
Term
This drug class is used for refractory ICP.
Definition
High dose-barbiturates eg pentobarital
Term
Actions of barbiturates for refractory ICP.
Definition
Induces pentobarbital coma
Improves vasomotor tone
Supresses metabolism
Term
Complication of barbiturate use.
Definition
Myocardial suppression = decreased CO & HoTN
Term
Rx of myocardial suppression in barbiturate use. (4 classes)
Definition
Crystalloids
Colloids
Inotropes
Vasoactive drugs
Term
What can you monitor to judge pentobarbital dosing?
Definition
EEG
Term
Two meds to induce barbiturate coma.
Definition
Pentobarbital
Thiopental
Term
Why are barbiturate comas induced? (5)
Definition
Tx uncontrolled ICP
Suppress cerebral metabolic activity
Dec. cerebral O2 needs
Blunt effects of noxious stimuli
More tolerant of position changes
Term
These are used to prevent vomiting & aspiration or to feed in barb coma.
Definition
NG/OG
Term
This is tech to judge level of coma.
Definition
EEG (BIS)
Term
Two parameters to maintain for ICP/hemodynamics.
Definition
MAP
CPP
Term
Rx used to reduce BP with ICP issues.
Definition
Nipride
Term
This medication is used to maintain serum osmolarity <310 mOsm/KG. Results occur in about 20 min.
Definition
Mannitol 20%
Term
What do you need to keep in mind when giving Mannitol 20%?
Definition
Keep hydrated to prevent renal failure
Term
Use ____ to pull fluid into vascular system.
Definition
albumin
Term
Other diuretic to use with ICP
Definition
Lasix
Term
This drug class is not effective with acute head injury.
Definition
Corticosteroids
Term
Options for CSF draining
Definition
Intermittent/Continuous
Term
What do you need to document with cSF drainage?
Definition
Appearance & Amt
Term
Why is CSF drained?
Definition
Dec ICP
Term
Why do you drain against a pressure of 15-20 cm of water when draining CSF?
Definition
Prevent collapsing of cerebral ventricles
Term
With fluid replacement in ICP maintain what fluid status to maintain CPP.
Definition
Euvolemic or slighlty hypervolemic
Term
VS monitoring IICP
Definition
Monitor frequent neuro checks
Watch for trends in readings
Term
Intubate with GCS of __ or less.
Definition
8
Term
What may you need when intubating pt GCS <8 to intubate?
Definition
Short acting paralytic & sedative
Term
Maintain what precautions with airway mgmt of IICP ventilated pt?
Definition
C-spine
Term
If IICP pt has adequate airway use what for O2?
Definition
100% non-rebreather mask
Term
With IICP pts avoid _________ unless there are signs of cerebral herniation.
Definition
Hyperventilation
Term
Method to keep pt in neutral position.
Definition
Log roll
Term
Method to prevent IICP pt from doing valsalva.
Definition
Exhaling
Term
Positioning IICP pt
Definition
Head neutral
HOB 15-30 or reverese Trendelenberg
(Use position that promotes lowest ICP)
Term
What should you base your nursing cares on with IICP pt?
Definition
Monitor ICP & stop when pressure increases.
Term
For each degree above normal there is a __-__% increase in BMR.
Definition
10-13
Term
IICP Pt:
Limit sxn to __s and __passes per time.
Hyperoxygenate with 100% pre & post.
Definition
10; 2
Term
What do you need to assess for when ET tube is removed from IICP pt?
Definition
Dysphagia
Term
What fluid & electrolytes do you need to monitor c IICP pt?
Definition
UO
Glucose
Electrolyte levels
Term
No sweating, shivering or variation in temp.
May get as high as 41 C or higher.
Definition
Central fever
Term
Shivering prevention c central fever.
Definition
Wrap extremities in towels &/or use thorazine.
Term
Positioning to decrease spasticity.
Definition
Flex thighs & rotate trunk
Term
Move extremities of IICP pt how?
Definition
Slowly
Term
Turn head towards side exercised if what?
Definition
Extremities are flexed
Term
For spasms of muscles or if hands are clenched. Relaxes muscle contractions in hands by putting pressure on muscle insertions.
Definition
Hand cone (Hard)
Term
Beds used for IICP
Definition
Roto-kinetic
Term
What do you want to do with IICP pt r/t GU?
Definition
DC foley asap, intermittent cath q 4-8 hrs.
Term
Shift of brain tissue through an opening at the base of the skull from an area of high pressure to an area of low pressure.
Definition
Herniation of brainstem
Term
Causes of brainstem herniation
Definition
Rapid increase of a hematoma, tumor or cerebral edema.
Inc ICP beyond compensatory potentials.
Term
Lateral & downward movement of temporal lobe.
Definition
Uncal herniation
Term
Pupil changes in uncal herniation
Definition
Unilateral dilating pupil c change in LOC.
Term
Downward movement of cerebrum & diencephalon to brainstem.
Definition
Central herniation
Term
Change in LOC is 1st subtle change in this kind of herniation
Definition
Central
Term
Downward displacement of brainstem through foramen magnum.
Definition
Infratentorial herniation
Term
2 types of supratentorial herniation
Definition
Uncal & Central
Term
Why did we not worry about ethical considerations with brain death prior to 1968.
Definition
No vents
Term
1988 ANA states that the nurse has the duty to what?
Definition
Prevent pain & suffering
Term
Brain death test where vent is withdrawn and wait 10 min to see if pt breathes.
Definition
Apnea test
Term
Etiology brain tumors
Definition
Hereditary
Cranial irradiation
Chemical exposure
Term
Brain tumors highest incidence demographics.
Definition
Young children
50-70 yo
Term
Fastest grown and most malignant brain tumor
Definition
Glioblastoma multiforma grade III or IV or astrocytoma
Term
First Sx Glioblastoma multiforma
Definition
HA; seizures
Term
Usually progression of disease for Glioblastoma multiforma.
Definition
Usually death, quickly. Some can live 8-9 yrs
Term
Slow growing, usually benign brain tumor.
Definition
Meningioma
Term
Danger of meningioma
Definition
Intercranial shift; IICP
Term
Where do brain tumors commonly metastasize to?
Definition
They don't usually
Term
Judgement & personality lobe
Definition
Frontal
Term
Sensory & visual lobe
Definition
Parietal
Term
Psychomotor seizures lobe affected
Definition
Temporal
Term
Visual disturbances lobe
Definition
Occipital
Term
Coordination & equilibrium lobe
Definition
Cerebellum
Term
This type of tumor has endocrine dysfunction, visual deficits & HA.
Definition
Pituitary
Term
Most common clinical presentation brain tumors.
Definition
Changes in LOC, HA (worse in AM)
Seizures, Vomiting
Term
Tx Brain tumors
Definition
Chemo
Radiation
Resection
Term
Diagnostics brain tumors
Definition
CT/MRI w/ or w/o dye
EEG
Endocrine studies if pituitary suspected
Term
If the chemo used for a brain tumor does not cross BBB how do you delivery it?
Definition
Via Ommaya reservoir (under scalp, straight into ventricles)
Term
Tx of choice for inoperable tumors or tumors not completely resected
Definition
Radiation
Term
Surgical opening into cranial cavity. Use a series of burr holes.
Definition
Craniotomy
Term
Deformed skull fix/bone flap removed surgery
Definition
Cranioplasty
Term
removal of bone flap (can store in lab or abdomen)
Definition
Craniectomy
Term
This type of tumor Tx technique includes:
Use of skull frame
Locate tumor by various computerized measurements
Use laser beam for deep tumors (less damage)
Biopsy tumor
Definition
Stereotactic
Term
This type of Tx includes:
Radiation to precise area of brain
Heavily shielded helmet
One Tx is all pt can take for life.
Definition
Gamme knife (not actual knife)
Term
HOB/monitoring post cranial surgery?
Definition
30 deg (to inc venous drainage)
VS
Neuro checks
Monitor ICP
Term
Keep ____ between 32-35 mm HG to decrease cerebral vasodilation. (ICP)
Definition
PaCO2
Term
Rx to promote normal ICP
Definition
Osmotic diuretics (mannitol)
Glucocorticoids
Term
Why are glucocorticoids Rxd post cranial surgery
Definition
Treat cerebral edema
Term
CSF drainage system (Left on for 24-48 hrs)
Definition
Ventriculostomy
Term
Drip chamber of ventriculostomy should be __-__ cm above what?
Definition
15-20 H20;
Foramen of Monroe
Term
Drain CSF against what?
Definition
Pressure
Term
How do you monitor for CSF drainage?
Definition
Check for glucose or halo on dressing. If pt is swallowing a lot. May come out of ears, nose or throat.
Term
Check pH of gastric content & Tx with H2 antagonists or antacids for this issue.
Definition
Stress (Curling's) Ulcer
Term
Why is CSF drainage so serious?
Definition
Bacterial infection possibility
Term
Why is CSF drainage so serious?
Definition
Bacterial infection possibility
Term
Endocrine problem with cranial surgeris
Definition
Diabetes Insipidus
Term
What must you not to in order to prevent contamination of area leaking CSF?
Definition
Do Not:
Suction nose or use nasal packing.
No fingers in nose or ears
Term
What must you do to prevent CSF contamination?
Definition
Dressing under nose. Dressing under ear and turn to side of leak.
Term
positive when the leg is bent at the hip and knee at 90 degree angles, and subsequent extension in the knee is painful (leading to resistance).
Definition
Kernig's sign
Term
The appearance of involuntary lifting of the legs in meningeal irritation when lifting a patient's head off the examining couch, with the patient lying supine.
Definition
Brudzinski's sign
Term
Your post craniotomy pt. is pulling at his lines, what do you?
Definition
Put mits on. Restraining inc ICP.
Term
To dec. risk of IICP avoid neck ___ or ________.
Definition
flexion; turning
Term
If large bone flap or mass is removed place patient on ___________ side to decrease venous congestion of operated site.
Definition
Unoperated
Term
What do you base your care of potential IICP pt on?
Definition
ICP.. if goes up stop what you are doing.
Term
What does IICP pt need to avoid?
Definition
Coughing,sneezing, straining to have bowel movement
Term
You IICP pt has a change of LOC, what technical problem could be happening?
Definition
Lack of shunt patency
Term
New onset of seizures post cranial surgery could indicate what?
Definition
Bacterial meningitis
Term
Fluid endocrine problems pt could develop.
Definition
DI & SIADH
Term
Most important aspect neuro assessment.
Definition
LOC
Term
Oval pupils are indicative of what?
Definition
Intracranial HTN
Term
HR Head injuries
Definition
Irreg HR can progress to bradycardia
Term
BP change Brain injury
Definition
Widening pulse pressure
Term
Temp change brain injury
Definition
Lack of temp regulation r/t hypothalamus damage
Term
Most sensitive indicator cerebral functioning
Definition
LOC
Term
What should you try to find out about pt asap upon admission?
Definition
Who they are & who to call b/c LOC maychange
Term
Aspects of GCS
Definition
Eye Opening
Verbal Response
Motor Response
Term
Lowest GCS score
Definition
3
Term
Score of __ intubate, Score of __ coma.
Definition
8;6
Term
Accepted/recommended noxious stimulation
Definition
Nailbed pressure
Term
What does GCS evaluate?
Definition
Coma; not brain stem function
Term
Your patient has a head injury from a car wreck. He was driving under the influence, what is not applicable?
Definition
GCS - not for altered sensorium
Term
Pt tries to remove noxious stimulus
Definition
Localization
Term
Who is GCS limited for eval?
Definition
Intubated/sedated
Swollen eyes
Wired jaws
Term
GCS 3; flexion & internal rotation at wrist, shoulders & LEs internally rotated.
Definition
Decorticate
Term
Part of brain damaged in decorticate posture.
Definition
Diencephalon (thalamus & hypothalamus)
Term
GCS 2; External & internal rotation of upper and LEs w/head extended.
Definition
Decerebrate
Term
Part of brain damages in decerebrate
Definition
Mid-brain or pons lesion
Term
Pinpoint, nonreactive pupils
Definition
Metabolic coma
Term
Dilated & fixed pupils
Definition
Imminent brain death
Term
Both eyes in same position in eye socket
Definition
Conjugate
Term
Eyes in different position horizontally
Definition
Disconjugate
Term
Eyes in different position vertically
Definition
Skewed
Term
When move head to right, eyes to left.
Definition
Present oculocephalic reflex (doll's eyes)
Term
Abnormal Oculocephalic reflex indicates _______ injury; absent indicates significant brainstem injury.
Definition
Brainstem
Term
What must you verify before checking oculocephalic reflex?
Definition
Absence of cervical injury
Term
Used to test brainstm function; supine w/head flexed 30 degrees; 20-30 mL ice water squirted into ear canal.
Definition
Oculovestibular reflex (Iced water calorics)
Term
What do you need for iced water calorics?
Definition
Intact tympanic membrane
Term
Conjugate movement toward stimulus
Definition
Normal oculovestibular reflex (brainstem intact)
Term
Disconjugate movement towards stimulus or absent movement in oculovestibular reflex indicative of what?
Definition
Abnormal/absent oculovestibular reflex
Term
This protective reflex requires cranial nerve V & VII
Definition
Corneal
Term
These protective reflexes require cranial nerves V, VII, IX & X
Definition
Cough & gag reflexes
Term
Aspects of Cushing's Triad (IICP)
Definition
Systolic HTN (widening pulse pressure)
Bradycardia
Irregular respirations
Term
This test reflects integrity of all brain functions.
Definition
Mental status exam
Term
This test checks sensory & motor functioning of all 12 cranial nerves.
Definition
Cranial nerve testing
Term
Indicates damage or injury to specific nerve roots.
Definition
Evaluation of sensation
Term
Tests integrity of somatic system
Definition
Evaluation of motor function
Term
This test visualizes calcifications, tumors, intracrainial shifts, herniation, brain edema, cysts & bleeds.
Definition
CT scan
Term
Check this before CT
Definition
Allergies & renal status
Term
This test shows greater detail; visualizes brainstem injuries, hemorrhage, infarcts & non-hemorrhagic lesions.
Definition
MRI
Term
What do you need to check before MRI
Definition
Metal
Term
Detects brain function rather than anatomy; detects epilepsy, dementia, CVA, trauma & mental illness. Can see brain light up differently for different senset.
Definition
Positron Emission Tomography (PET)
Term
Definitive test for vascular problems; can use with angioplasty or coiling of cerebral aneurysm.
Definition
Angiography
Term
Visualize spinal column for herniated discs, tumors, congenital problems.
Definition
Myelogram
Term
For this dye type in myelogram head up 30-45 degrees.
Definition
Water based dye
Term
For this type of myelogram dye lie flat 6-24 hrs; assess for HA & spinal leak.
Definition
oil based dye
Term
Records brain waves & checks for abnormal electrical activity.
Definition
EEG
Term
Detects muscle activity by electrical stimulation. Small needles placed into certain muscles that are supplied by each nerve root.
Definition
Electromyogram (EMG)
Term
Indicates inc or dec blood flow during cerebral vasospasm to determine brain death.
Definition
Cerebral blood flow studies (CBFS/ Brain scanning)
Term
Used to detect carotid artery occlusion or CVA.
Definition
Transcranial doppler ultrasound
Term
Used to measure CSF & send specimen to lab.
Definition
Lumbar puncture
Term
Puncture @ C1/C2 -- used to measure CSF & send specimen.
Definition
Cisternal puncture
Term
ICP provides info about intracranial ________.
Definition
Compliance
Term
Head contents -
__% blood
__% CSF
__% Brain tissue.
Definition
10;10;80
Term
3 contents of head
Definition
Blood
CSF
Brain tissue
Term
The amt of pressure that must be maintained at a correct level so that O2 and glucose get to the brain.
Definition
Cerebral perfusion pressure (CPP)
Term
CPP equation
Definition
CPP=MAP-ICP
Term
Provides approximate cerebral blood flow (CBF)
Definition
CPP
Term
CPP >__ mm HG ideal.
CPP <__ mm HG too low.
Definition
80; 60
Term
Normal ICP
Definition
3-15 mm HG
Term
High normal ICP
Definition
10-15
Term
What can cause ICP >100 mm Hg
Definition
Coughing
Term
20-25 mm Hg ICP pressure; ominous sign
Definition
Uncontrolled ICP
Term
Sustained ICP >60 mm Hg = ______.
Definition
Death
Term
Position at level of foramen of monro; HOB >30, fluid can be REMOVED witht his type of ICP monitoring device.
Definition
Fluid-filled transducers
Term
Zeroed at insertion time & transducer located at tip of catheter. No adjustment with movement of head. (ICP monitoring device)
Definition
Fiberoptic Catheter
Term
2 types ICP monitoring devices.
Definition
Fluid filled
Fiberoptic
Term
Placed in lateral ventricle of head, drains CSF
Must level & re-level w/head movement.
Definition
Intraventricular catheter (Ventriculostomies)
Term
Tip sits in subarachnoid space, unable to drain CSF, must level c movement of head.
Definition
Subarachnoid bolt or screw
Term
No adjustment needed c head movement, easiest to place, unable to drain fluid.
Definition
Epidural catheter.
Term
Catheter placed into brain tissue, can't drain.
Definition
Intraparenchymal catheter
Term
Accurate and reliable catheter that can be placed epidural, subdural or parenchymal. Can't drain.
Definition
Fiberoptic
Term
Combines fluid-filled intraventricular catheter drainage system with fiberoptic transducer. Wave forms in relationship to pt's heart beat. Can't drain.
Definition
Newest! (no name given in notes, woohoo)
Term
Corresponds to each heart beat (p1, p2, p3)
Definition
Pulse waveforms
Term
P2 = to or >P1
Definition
IICP & dec cerebral compliance
Term
When does plateau wave A occur?
Definition
Sudden, sustained rise in ICP
Term
How long does A wave last?
Definition
5-20 min
Term
ICP 50-100 & sustained.
Definition
A wave
Term
Can RNs irrigate CSF catheter?
Definition
No
Term
Common between 15-25 yo w/ peaks in infants and elders. M:F 2:1
Definition
Acute head injury
Term
Moving head hits stationary object.
Definition
Acceleration/Deceleration
Term
Movement of brain back & forth inside the skull
Definition
Coup contrecoup
Term
Head injury damage
Definition
Bruise/damage/swelling
Term
Presents with racoon eyes or panda eyes
Blood or CSF from nose
Definition
Anterior basilar skull fracture
Term
Bruising over mastoid bone
Blood & CSF from ears
Definition
Posterior skull fracture
Term
Bruising over mastoid bone
Definition
Battle's sign
Term
_________ cause tearing of brain tissue; _______ cause bruising of brain tissue.
Definition
Lacerations
Contusions
Term
Lucid then deteriorate rapidly head injury.
Definition
Acute epidural hematoma
Term
Epidural bleed is between ____ and ____.
Definition
cranium & dura
Term
2nd in mortality & morbidity head injury. Happens a lot in older people. Develops over 24-72 hrs and is subacute 72 hrs - 2 wks.
Definition
Subdural
Term
Tx subdural bleed.
Definition
Burr holes & drain clot
Term
Bleed into parenchyma of brain; falls, MVCs, anticoags
Definition
Intracerebral bleed
Term
Caused by GSW, knives, arrows etc.
Definition
Penetrating injury to head
Term
Diffuse injury with amnesia <6 hrs; tearing of brain tissue & nerve cells, mortality 60-70%
Definition
Diffuse injuries
Term
Located between arachnoid & pia mater; cerebral vasospasms possible 3-7 days.
Definition
Traumatic subarachnoid head injury
Term
Tx vasospasms with traumatic subarachnoid.
Definition
Minodipine (Ca++ channel blocker)
Term
May not be recognized or symptomatic, ppl may think lazy.
Definition
Mild TBIs
Term
Mild, HA, difficulty thinking, can last wks to months.
Definition
Concussion
Term
Related to biophysical & biochemical changes to cerebral perfusion.
Leads to neuronal dysfunction.
Definition
Secondary injury
Term
With this brain injury all body functions can be affected.
Definition
Acute brain injury
Term
Possible system impact ABI
Definition
Inc. glucocorticoids & mineral corticoids.
Release ADH/no ADH (SIADH/DI)
Inc. catecholamine release (HTN & dysrhythmias)
Hyperglycemia
Occlusions/DIC/anemia
Pneumonia/secondary infection
Dec. GI motility & inc. gastric acid production (Curling's ulcer)
Term
Crescendo to decrescendo to apnea(then repeats) respirations (ABI)
Definition
Cheyne-stokes
Term
Very rapid shallow breathing, indicates involvement of tentorial herniation, may retain CO2
Definition
Central neurogenic hyperventilation
Term
We only hyperventilate a patient when what is happening?
Definition
Brainstem herniation - stopgap measure
Term
Imbalance central neurogenic hyperventilation leads to
Definition
Resp. acidosis (CO2 vasodilates, inc. blood, inc. ICP)
Term
Prolonged inspiration withtentorial herniation.
Definition
Apneusis
Term
Patternless breathing with long periods of apnea; herniation at foramen magnum.
Definition
Ataxia
Term
Mesures both arousal & awareness
Definition
GCS
Term
GCS 12-14
Definition
Mild head injury
Term
GCS 9-12
Definition
Moderate head injury
Term
GCS 8 or less
Definition
Severe head injury
Term
No ____ tubes in head injury.
Definition
Nasal
Term
Blind in outside or inside visual fields.
Definition
Bitemporal hemianopsia
Term
Blind in R or L side of each eye
Definition
L & R homonymous
Term
What must you use when delivering mannitol?
Definition
Filter needle
Term
ICP that does not respond to Tx.
Definition
Refractory
Term
Rx to decrease workload of the brain.
Definition
Barbiturates
Term
Records pt's brainwaves
Definition
Bispectral index
Term
What should CSF look like?
Definition
Clear or yellowish, no blood or cloudiness (infection)
Term
Common causes of this are MVCs, diving, falls, contact sports and GSWs. Commonly 15-20 yo males; drugs/ETOH involved.
Definition
SCIs
Term
Most common mechanism of injury in cervical injuries. Ligament that connects spinous processes tears. Most unstable.
Definition
Hyperflexion
Term
Whiplash injury; most common SCI tear - anterior ligament & stretches cord.
Definition
Hyperextension
Term
Vertical compression injury
Definition
Axial loading
Term
5 MOIs SCIs
Definition
Hyperflexion
Hyperextension
Penetrating Injury
Rotation
Axial loading
Term
Most at risk level of injury
Definition
Cervical & lumbar
Term
This type of SCI falls on rear & sacrum pushes up
Definition
Thoracic & sacral
Term
Total loss of motor or sensory function below level of injury
Definition
Complete SCI
Term
Result of mechanical forces that disrupt neuro tissue and/or its vascular supply.
Definition
Patho SCI
Term
Occurs at moment of impact
Definition
Primary injury
Term
Complex biochemical proceses affecting cellular function.
Spinal cord ischemia & loss of neuro function.
Definition
Secondary SCI
Term
Complete injuries
Definition
Tretraplegia
Paraplegia
Term
Transection or lesion of 1/2 spinal cord; rare; usually penetrating trauma. Mixed loss of motor & sensory function.
Definition
Brown-Sequard syndrome
Term
Brown-Sequard syndrome:
Loss of ____ function on same side of injury & loss of _____ and ____ on opposite side of injury.
Definition
Motor; pain/temp
Term
Associated with cervical hyperextension-hyperflexion & hematoma formations in center of cord. Recovery depends on extent of hemorrhage and ability to release pressure placed on spine.
Definition
Central cord syndrome
Term
Central cord syndrome:
Motor & sensory deficit more pronounced in ___ extremities than ___ extremities.
Definition
Upper; lower
Term
Loss of motor function & loss of sensations of pain & temp below level of injury. Below level of injury position sense & sensations of pressure & vibration remain.
Compression of anterior spinal cord due to flexion injury.
Definition
Anterior cord syndrome
Term
Associated with cervical hyperextension injury c damage to posterior cord. Loss of position sense, pressure & vibration below level of injury. May or maynot be able to ambulate due to loss of position sense.
Definition
Posterior cord syndrome
Term
What is intact in posterior cord syndrome?
Definition
Motor function & sensation of pain
Term
Condition that can occur immediately or within several hours after traumatic injury to spinal cord. No Tx, duration variable (days towks)
Definition
Spinal shock
Term
Complete loss of all muscle tone & normal reflex below level of injuyr; body loses its ability to regulate temp (poikilothermia)
Definition
Spinal shock
Term
lose ability to vasodilate/constrict.
Definition
Spinals shock
Term
How do youknow spinal shock has resolved?
Definition
DTRs below level of injury return & skel muscles become spastic (spasticity can be long or shor term)
Term
Form of shock associates with cervical and upper thoracic injuries. Results from injury to descending sympathetic pathways in spinal cord to systemic vasculature of heart and peripheral vascular resistnce (loss of vasomotor tone)
Definition
Neurogenic shock
Term
Neurogenic shock is form of _______ shock. Vasodilation leads to hypervolemia & hypotension. Interruption of SNS leads to bradycardia and decreased CO.
Definition
Distributive
Term
Life threatening complication that occurs after acute phase (after spinalshock has resolved)
Pts with injury at T6 or above
Definition
Autonomic Dysreflexia
Term
triggers autonomic dysreflexia
Definition
Full bladder
pain
Distended bowel
Pressure ulcers
Drastic change of temp
wrinkle in sheet
ejaculation
Term
Trigger produces ______ discharge that causes ______ of the blood vessels (below level of injury) that leads to extreme, rapid ______.
Definition
sypathetic; vasoconstriction; hypertension
Term
Autonomic dysreflexia ____ below level of injury and ______ above level of injury.
Definition
vasoconstriction; vasodilation
Term
Nsg actions autonomic dysreflexia
Definition
Immediately raise HOB
Try to find cause
Term
HA, HTN, flushed & sweating above level of injury, pale below injury, pupil dilation
Definition
Sx autonomic dysreflexia
Term
Rx autonomic dysreflexia (antihypertensive)
Definition
nifedipine, methyldopa, hydralazine, diazoxide, can use nitropaste at home.
Term
15% of trauma pts with injury will have _____ _______ injury.
Definition
Cervical spine
Term
What test is done to R/O SCI?
Definition
CT scan
Term
____ may be used as definitive diagnosis of SCI.
Definition
MRI
Term
This Rx SCI prevents posttraumatic spinal cord ischemia, improves energy metabolism, restores extracellular calcium, improves nerve impulse conduction, Reduce edema.
Definition
Methylprednisone
Term
Guidelines for methylprednisone with SCI.
Definition
Give within 8 hrs of injury
Loading dose weight based delivered over 15 min.
Start infusion and give over next 23 hrs.
Term
When can you not give methylprednisone for SCIs.
Definition
After 8 hrs
Open ord injuries
Term
Anterior/posterior ligaments & 1 lamina or spinous process are intact.
Definition
Stable
Term
Ligaments holding spine together torn; cannot maintain normal alignment.
Definition
Unstable
Term
Used to realign vertebra and remove any bone fragments, usually seen with unstable fractures.
Definition
Surgical mgmt
Term
Removal of lamina which allows for decompression and removal of bony fragments.
Definition
Laminectomy
Term
Fusion of 2 to 6 vertebral elements; uses bone parts or chips taken from iliac crest, cadaver or wire.
Definition
Spinal fusion
Term
Harrington rods placed on either side of the column to provide stabilization.
Definition
Rods
Term
Used when pt is stable and can be moved. Pins & vest.
Definition
Halo vest
Term
With any cervical injury watch for ______ on the back of hte head.
Definition
decubs
Term
Usually Txd with immobilization until fractures heal. May use body cast or fiberglass brace.
Definition
Thoracolumbar injury
Term
Why do we intubate C1-C5 usually?
Definition
Airway maitenance - edema can develop and not be able to intubate later.
Term
Injuries above TF have no SNS influence, what do their vitals loot like?
Definition
Bradycardia
HoTN
Term
Rx T5 and above
Definition
IVF & vasopressin for HoTN
Atropine for bradycardia
Term
Common psychological issue for SCIs.
Definition
Like to be in control
Term
T1 and > = _____
T2 and < = _____
Definition
quad; para
Term
____ and lower injuries can transfer selves.
Definition
C7
Term
A state of hyperthyroidism that can lead to death if not treated.
Definition
Thyrotoxic crisis (Thyroid storm)
Term
What is death from thyrotoxic crisis r/t?
Definition
Heart failure
Term
Major stressors, systemiv infections, DM out of control, MI, surgery, trauma, levothyroxine are all potential causes of what?
Definition
Thyrotoxic crisis
Term
Sx thyrotoxic crisis
Definition
Tachycardia, HTN, Fever irritable, termors, weakness, heat intolerance, Afib/angina/sob
Term
2 types of ppl at risk for thyrotoxic crisis.
Definition
UnDxd or inadequately treated hyerthryoidism
Term
Dx tests for thryotoxic crisis
Definition
Elevated T3 & T4
Decreased level of TSH
Term
Nsg actions thyrotoxic crisis
Definition
Lower BMR - cooling blankets
Tyelenol
Assess neuro & cardiac status
O2
Check blood sugar
IVF
propylthiouracil
Term
What drug do you NOT NOT NOT give during thyrotoxic crisis and why?
Definition
ASA - inc. free thyroid hormone levels
Term
Blocks conversion of T4 to T3 and binds iodine; therfore reduces the amt of circulating thyroid.
Definition
Propylthiouracil
Term
Block release of thyroid hormones
Definition
Iodide preparations SSKI & NaI
Term
Thyroid suppressants must be given __-__ hrs after anti-thyroid medication is administered.
Definition
1-2
Term
Use _____ for those sensitive to Iodine
Definition
Lithium
Term
Steroid that blocks conversion of T4 to T3, given IV.
Definition
dexamethasone
Term
Given to thyrotoxic crisis to decrease demand on the heart, not to Tx thyroid level.
Definition
B blockers (propanolol)
Term
If hyperthyroid medication does not work or patient is non compliant what can be given?
Definition
Radioactive iodine
Term
Given to hyperthyroid to minimize anxiety and promote rest.
Definition
Mild tranquilizers
Term
Removal of part of the thyroid gland.
Definition
Subtotal thyroidectomy
Term
What do you worry about post thyroidectomy
Definition
Effect on parathryoid (Ca++ & PO4-3)
Term
Avg onset 39 yo, women, usually anterior lobe of pituitary and non-malignant.
Definition
Adenomas (Pituitary tumors)
Term
Microadenoma <__cm, macroadenoma >__cm
Definition
1;1
Term
Can lead to hormone imbalances; deficiencies or excesses so can look different in everyone.
Definition
Pituitary tumors
Term
Hormones in pituitary (8)
Definition
ADH
Oxytocin
Prolactin
ACTH
TSH
GH
LH
FSH
Term
Location of pituitary tumor
Definition
Sella tursica
Term
HA, visual disturbances, dec libido, impotence, menstrual irregularities, personality, seizures, dementia, weakness, fatigue, cold sensitive, breast discharge can all be Sx of this disease.
Definition
Pituitary adenoma
Term
What cna brain tumors lead to?
Definition
Displacement & herniation
Term
Dx tools for brain tumor
Definition
Skull XRays
CT/MRI
Angiogram
Term
Rx for prolactin secreting tumors; shrinks prolactic secreting tumors in 1-6 months.
Definition
Bromocriptine (Parlodel)
Term
Pre-op for surgical Tx of pituitary adenomas (3)
Definition
Tx thyroid deficiencies
Pre-op dose hydrocortisone
Nasal antibiotic spay
Term
Surgical tx for macroadenomas
Definition
bifrontal craniotomy
Term
surgical tx of microadenomas
Definition
transphenoidal hypophysectomy
Term
freeze tumor with probe via transphenoidal route
Definition
Cryohypophysectomy
Term
What do you need to avoid post adenoma surgery?
Definition
Anything that inc. ICP
Do not remove nasal packing (impregnated with abx)
Term
Sella tursica is packed with fat from where?
Definition
Thigh
Term
4 things need to monitor carefully post adenectomy
Definition
CSF leak
Compromised airway
IICP
dsg on thigh, nose packing & surgical site
Term
Possible hormone issues after adenectomy, how do you tx this?
Definition
DI
vasopressin & IVF
Term
Possible infection r/t adenectomy
Definition
meningitis
Term
Oral care post adenectomy
Definition
toothettes, rinse mouth c chlorhexidine
Term
Caused by decrease in production or release of ADH; can be due to several causes eg lesion or injury of hypothalamus or pituitary gland; maybe after neurosurgeries eg transphenoidal hypophysectomies.
Definition
DI
Term
DI from brain tumors, IC, hemorrhage. Dec. amt of ADH produced.
Definition
Neurogenic DI
Term
DI r/t meds, elyte disturbances.
Definition
Nephrogenic (rare)
Term
Compulsive H20 drinking of 5 L or more/day.
Definition
Psychogenic (no toilet/sink access alone)
Term
Sx DI
Definition
dehydration; polydipsia; polyuria (>300 mL/hr)
Term
elytes affected by DI
Definition
Na; K; Cl
Term
SG DI urine
Definition
1.001-1.005 (no glucose)
Term
Blood osmo DI
Definition
concentrated & hypernatremic
Term
DI has similar Sx to ____. You can tell the difference b/c DI has no _____ in urine.
Definition
DKA; glucose
Term
Neuro Sx DI
Definition
Confusion
Irritability
Coma
Seizures
Term
DI lab values:
Serum sodium >____.
Urine osmo < ___
Serum osmo >____
SG < ____.
Definition
145; 200; 300; 1.005
Term
Drastic change DI experiences.
Definition
Wt loss (6-7 lbs in 24 hrs)
Term
Way to visualize lesions in neurogenic DI
Definition
CT/MRI
Term
What major complication of DI do you worry about?
Definition
Hypovolemic shock (HR/BP are LATE sign)
Term
DI stable use _____ soln; DI unstable use _______ soln.
Definition
hypotonic; isotonic
Term
Why give isotonic to unstable DI pt?
Definition
Keep fluid in vasculature to avoid shock
Term
Hormonal replacement given SQ, IV, IM to DI pts (may cause angina or MI b/c vasoconstricts)
Definition
vasopressin
Term
ADH replacement can be given intranasally & does not vasoconstrict. Works within 20 min.
Definition
Desmopressin acetate (DDAVP)
Term
Caused by high secretion of ADH. Associated c disease or trauma to posterior pituitary
Definition
SIADH
Term
What other pts can you see SIADH in?
Definition
Oat cell lung cancer; chemotherapy recipients
Term
Sx SIADH
Definition
Sodium < 135
Urine sodium <20 meq/L
Urine hyperosmolarity
Serum hypoosmolarity <275 mOsm
Anasarca
SG > 1.030
Confusion, irritability, seizures, HA (cerebral edema)
Term
Biggest concern with SIADH
Definition
Brainswelling
(HA, LOC change, seizures, muscle twitches)
Term
What precautions are SIADH pts on?
Definition
Seizure
Term
Fluid restriction SIADH
Definition
600-1000
Term
Fluid restriction causes secretion of ______; therefore kidneys conserve sodium & SIADH corrects self.
Definition
aldosterone
Term
Rx unsuccessful fluid restriction c Na <115
Definition
IV 3-5% saline soln; prefer to give in central line b/c burns badly
Term
Na goal for DI c Na<115
Definition
Raise to 120-125 mEqs over 24-48 hrs
Term
What can happen if you raise Na too fast?
Definition
Fluid shifts & seizures
Term
Rx SIADH (4 w/reasons)
Definition
Lasix to remove excess fluid c cardiac problems
K+ replacement if needed
Dilantin (control seizures r/t brain swelling)
Demeclocycline (block ADH action and Tx chronic SIADH)
Term
Life threatening emergency seen most often in type 2 diabetics. More common in >60 yo. Mortality rate 50%
Definition
Hyperglycemic Hyperosmolar Nonketotic Syndrome (HHNS)
Term
Provoked by stress response or meds (thiazides, dilantin, cimetidine)
Definition
HHNS
Term
Sx HHNS
Definition
Polyuria
Polydipsia
Hypersomolality (>350 mOsm, may lose 15-20% body fluid)
Ortho HoTN
Hyperglycemia 300-1000
High serum osmo
No ketones present due to small amt insulin
Lethargy
Coma
seizures
hypovolemic shock
Term
Give ___ IV for hypotensive w/sx of shock
Definition
NS IV
Term
Give __ for normal Bp intracellular loss (replace 1/2 estimated H20 loss in 12 hrs and remainder over 24)
Definition
1/2NS
Term
Complications r/t HHNS
Definition
Flash pulmonary edema
Risk emboli r/t blood viscosity
Term
Add _____ to IV soln when blood glucose drops to 250 with HHNS
Definition
dextrose
Term
What does adding dextrose do for HHNS pt?
Definition
Prevents cerebral edema & dropping to hypoglycemic state.
Term
What kind of insulin can you give IV?
Definition
Short acting only
Term
What is IV insulin bolus dosage based on?
Definition
Wt & blood glucose level
Term
HHNS maintain blood sugar __-__ mg/dL
Definition
80-110
Term
3 elytes need to replaces with HHNS
Definition
K+
PO4-3
Mg++
Term
3 Rx for elyte imbalance in HHNS
Definition
KCl
KPO4-3
MGSO4-3
Term
____ forces K+ intracellulary so serum K+ will drop.
Definition
Insulin
Term
Monitor for ______ with HHNS, can sometimes be mistaken for DKA.
Definition
Acidosis
Term
Hypomagnesemia can cause a type of Vtach called what?
Definition
Torsade's de Pointe
Term
Why would you not want to give an IICP pt with DI a fluid bolus?
Definition
Inc. ICP
Term
Inc. in vol of 1 equals dec in vol of 1 or 2 of the others (ICP)
Definition
Monroe-Kellie Hypothesis
Term
Why would you not give ASA to pt with head trauma to control temp?
Definition
Bleeding
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