Shared Flashcard Set

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Control Resp Function
test 2
18
Pathology
Undergraduate 1
02/20/2013

Additional Pathology Flashcards

 


 

Cards

Term
Do Oxygen and Carbon dioxide exchange for one another?
Definition
NO never
Term
Functions of Lungs
Definition
  • Gas exchange- Moves 02 into blood- Removes Co2 from blood
  • Blood Storage
  • Regulate Vasoconstricting Substances- Brdykin, ACE, Heparin
Term
Mechanics of breathing
Definition
  • Chest expands and sucks air in- movement of muscles is what causes you to breath!!!!!!!

Inspiration- decrease pressure increase space

Expiration- Increase pressure decrease space

Term

Compliance of lung Depends on

 

Has to be able to stretch and recoil

Definition
  • Elastin & Collagen Fibers
  • Water content
  • Surface tension
Term

Compliance: Elastic Stretch & Recoil

 

Empysema

Normal

Fibrosis

 

Definition

Empysema-stiff lung-stretch does not recoil

Normal-stretch recoil =

Fibrosis-harg lung- can not stretch

Term

What controls Surface tension?

 

Definition
  • Surfactant- created by type 2 alvero cells- keep lung from collapsing- controls water surface tension
Term

-Work of breathing-

  1. How is air xchange meassured
  2. Stiff non-compliant lung
  3. Obstructive airways
Definition
  1. TV x Resp rate=normal 6000ml
  2. keep TV low & increase rate
  3. Take deeper breath at a slower rate
Term

Dead Space?

 

2Types of Shunting?

Definition
  • Anatomic Dead Space- normal- Air that does not reach exchange level 30% of tidal volume
  • Physiologic dead space-abnormal- air gets to alveolus but 0 xchange= shunting
  1. Anatomic-obstuction alveoli blocked
  2. Physiologic- Alveolus dysfunctional inadequete perfusion d/t edema, excessive secreations
Term
3 Points of Respiration... Must have these to have good respiration
Definition
  • Ventilation-has to get in and out (movement)
  • Perfusion- must have good blood flow
  • Diffusion- need to have normal alveolus
Term

A. Normal Unit

B. Dead Space

C. Shunt unit

Definition

A. Normal vent/perfusion

B. Not exchanging= Vent>perfusion ie. Pulm emoblism/infaction

C. Perfusion>Vent

Term

How are you perfusion zones effected?

1=minimal perfusion

2= intermediated- go up stairs

3=continuous- sitting- most take place here

Definition
Zones are effected by how the patient is laying/position= this is why we must keep out patient moving
Term

Factors Affecting Zones

 

Definition
  • Position-upright perfusion decreased
  • Hemodynamics- BP/V
  • Increased Perfusion Exercise- recruitment & destention
  • Hypoxic Vasoconstriction-
Term

During running or increase excersie what happens in lungs

 

Definition
Distention & recruitment= pull more fluid to get better perfusion in lungs
Term

Movement of gases across the alveolar cap membrane

 

What affects this

 

Definition

Diffusion

  • gass pressure
  • available surface area
  • membrane thickness
  • characteristics of gas
Term
How does 02 move from Alveolus?
Definition
  • 02 from Alveolus to cap along concentration gradient
  • 02 not easily dissolved in plasma
  • inside cap 02 moved to RBC to combine with HG
  • 02 Dissociated from HG to where cap has lower 02
Term
Carbon Dioxide Transport
Definition
  • 5% Disolved in Plasma
  • 20% carried by HG
  • 75% work in buffer system= CARBONIC ANHYDRASE ALLLOWS THIS to maintian into buffersystem to keep our ph in control.
Term

Neural Control of Resp- Resp center controlled by?

2 groups that control this?

Definition
  • Medulla & Pons
  1. Dorsal Group- inspiration- control phrenic nerve diaphram
  2. Ventral group- inspir & exspir- spinal motor neurons (inercostal &adominol)
Term

Chemoreceptors Adjust Resp Rate

  1. Central Chemoreceptors
  2. Peripheral Chemoreceptors

What looks for 02?

Definition
  1. Measure PH in cerrebrospinal fluid- increase resp when ph decreased -resp center in brain if acidotic(stimulus) increase rate a little bit, but will only do this for awhile(COPD lose this)
  2. Carotid &Aoric bodies meassure PO2 in arterial blood, increase resp when Po2 <60. HYPOXIA STIMULUS
  3. Chemoreceptors
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