Term
| What is Bipolar Disorder? |
|
Definition
-cyclic disorder
-recurrent flucutations in mood
-episodes of mania and depression |
|
|
Term
| Types of drugs for Bipolar Disorder |
|
Definition
1. Mood stabilizers (relieve,prevent)
2. Antipsychotics (severe episodes)
3. Antidepressants |
|
|
Term
|
Definition
1. Lithium
2. Antiepileptic drugs |
|
|
Term
|
Definition
| serotonin receptor blockade |
|
|
Term
|
Definition
1. Bipolar
2. Acute mania depression
3. ETOH, bulimia, schizophrenia |
|
|
Term
| Normal plasma levels for lithium |
|
Definition
|
|
Term
|
Definition
> 1.5 mEq/L
(hemodyalisis may be needed) |
|
|
Term
|
Definition
1. Diarrhea
2. Tremors (stress/caffeiene)
3. Polyuria
4. Goiter/hyperthyroidism
5. Teratogenesis |
|
|
Term
| drug interactions with Lithium |
|
Definition
1. Diuretics (MONITOR sodium levels)
2. NSAIDS (lithium toxicity, rental retention)
3. Anticholinergics (TCA, antihistamines)
-urinary retention |
|
|
Term
| T/F Low levels of sodium induce lithium toxicity |
|
Definition
|
|
Term
| Which NSAIDs can be administered with Lithium? |
|
Definition
|
|
Term
| Which NSAIDs should be avoided with Lithium therapy? |
|
Definition
ibuprofen & celecoxib
-increases renal reabsorption of lithium and leads to toxicity |
|
|
Term
| What type of anticholinergics should be avoided with Lithium? |
|
Definition
1. Antihistamines and TCA
b/c = abdominal discomfort can result from anticholinergic-induced urinary retention and polyuria |
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