Term
| Examples of Drug-Induced Skin Disorders |
|
Definition
Hypersensitivity/allergic reaction
Photosensitivity
Toxic Reaction
-Steven-Johnson syndrome
-toxic epidermal necrosis
-erythema multiforme
Drug-Induced Disease
-lupus
-acne |
|
|
Term
| Treatment of Drug Reactions |
|
Definition
stop the drug!!
antihistamines
systemic or topical corticosteroids
soothing baths or soaks |
|
|
Term
| Treatment of Photosensitivity |
|
Definition
prevention with sunscreens and clothing
systemic analgesics
systemic antihistamines for itching
prevent infection
moisturizers
cooling creams/gels |
|
|
Term
| Drugs Associated with SJS/TEN |
|
Definition
Sulfonamides
Cephalosporins
Penicillins
Fluroquinolones
Anticonvulsants
Allopurinol
NSAIDs
Others... |
|
|
Term
|
Definition
Usually occurs within the first four weeks of treatment
Prodromal NVD, myalgias, sore throat, arthralgias - flu-like symptoms
involvement of mucous membranes
widespread blisters and lesions
full thickness epidermal detachment - risk of infection |
|
|
Term
|
Definition
Stop the drug!
IV fluids/nutrition
Pain control
Eye care
Nasal saline
Oral hygiene and anesthetics
Topical antiseptics
Wound care |
|
|
Term
|
Definition
Phenytoin
Hydralazine
Isoniazid
Procainaminde
Others... |
|
|
