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Clinical Reasoning - Observati
(*)Observational Studies
11
Medical
Graduate
01/13/2009

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Cards

Term
TF
A single study can prove causation.
Definition
FALSE


A single study can only prove association
Term
T/F:

On their own, case reports and case series cannot test that hypothesis to show an assoc between exposure and dz.
Definition
TURE
Term
A _______ study uses a large group of ppl, a population, to look at the freq of exposures and dz.

*** remember, this still cannot prove CAUSATION, only assoc.***
Definition
Correlational Study

Can only show a + or - correlation

ALSO, the study is on the POPULATION, NOT THE INDIVIDUAL LEVEL ... ie, there is no way to prove that those who eat meat are the same inv=dividuals that have colon cancer

may lead to ecological fallacy
Term
a ____________- survey measures EXPOSURE and OUTCOME in a person AT THE SAME TIME.
Definition
Cross-Sectional

BC at the same time, limits ability to judge temporal relationship
Term
______________ studies use a group of ppl with a dz, and compare them to a group without the dz

when is this type ideal?
Definition
case-control studies

Very good when outcome RARE
Term
group of people who share a common characteristic or experience within a defined period
Definition
cohort study
Term
____ study = groups are chosen based on whether or not they have an exposure, and are compared as to whether they develope a certain outcome
Definition
Cohort study
Term
define a WORST CASE SCENARIO analysis
Definition
We assume that:

Everyone who was lost in the EXPOSED GROUP did fine

Everyone lost in the NOT EXPOSED GROUP die

Lost = left experiment (moved, descided not to keep attending)
Term
formula for RELATIVE RISK:
Definition
RATE OF EXPOSED / RATE OF UNEXPOSED


How to get RATE:
Number of ppl with outcome / total group

Do this for both groups, then divide

THis tells you Relative risk (ir, a person is 30x more likely than a nonexposed)
Term
Absolute Risk formula:
Definition
Absolute value of :

(Rate in expoised - rate in nonexposed)
Term
NNT formula:

(Number Needed to Treat)
Definition
the number of patients needed to be exposed to cure one

1/Absolute rusk reduction
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