Term
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Definition
Composition in bone 55%
in soft tissue 44%
in ECF 1% |
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Term
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Definition
| In bone: found in the form of hydroxyapatite crystals 85%; soft tissue 15%; and ECF as inorganic phosphates <0.1% |
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Term
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Definition
Most prevalent mineral in bone
Sources: 99% of total calcium found in skeleton as hydroxyapatite crystals; 1% in plasma, of which 50% is free (ionized) 40% bound to albumin/globulins and 10% complexed to anions |
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Term
| Cytokines responsible for bone metabolism |
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Definition
| IL-1, IL-4, IL-6; stimulate bone resorption |
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Term
| Hormones that affect bone metabolism |
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Definition
PTH, 1,25 DihydroxyVit D: Regulates bone mineral deposition, intestinal resorption and renal excretion
Others include thyroid hormone, estrogen, cortisol, insulin, GH |
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