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Clinical Chemistry Ch 12
Reproductive Endocrinology & Fetal Testing
39
Chemistry
Undergraduate 3
11/21/2010

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Term
fetus
Definition
unborn but recognizable human organism between 10 week's and 40 week's gestation
Term
human chorionic gonadotropin (hCG)
Definition
classic hormone marker of pregnancy produced by the placenta after the fertilized oocyte implants
Term
human placental lactogen (hPL)
Definition
hormone produced by the placenta and involved in maternal glucose and fat metabolism and mammary gland function
Term
endometrium
Definition
the lining of the uterus
Term
estriol
Definition
18-carbon steriod molecule that is the main estrogen found in pregnant women
Term
follicle
Definition
sac produced by the ovary containing an oocyte
Term
estrone
Definition
18-carbon steroid molecule that is less active than other estrogens
Term
estradiol
Definition
18-carbon steroid molecule that is the main estrogen found in non-pregnant women
Term
dehydroepiandrosterone
Definition
19-carbon molecule found in small amounts as a precursor to some estrogens in women and as a precursor to male sex steroids
Term
miscarriage
Definition
sudden unplanned evacuation of the uterus, ending pregnancy
Term
ultrasound
Definition
imaging technique that uses high-frequency sound waves to create images of internal organs, tissue, and blood vessels
Term
Sertoli cells
Definition
specialized cells in the seminiferous tubules of the testis that produce inhibin and factors that help sperm maturation
Term
prebubescent
Definition
before sexual maturity
Term
gonads
Definition
reproductive organs:  the testes in the male and ovaries in the female
Term
gametocyte
Definition
sperm cell or oocyte
Term
follicular phase
Definition
first half of the female menstrual cycle leading up to maturity of one follicle and release of an oocyte
Term
luteal phase
Definition
second half of the female menstrual cycle following ovulation and the dominance of the corpus luteum
Term
ejaculation
Definition
ejection of sperm cells and seminal fluid at orgasm
Term
Leydig cells
Definition
specialized interstitial cells of the testes surrounding the tubules that produce testosterone
Term
libido
Definition
sexual desire
Term
encephalocele
Definition
congenital opening in the skull with protrusion of brain tissue
Term
anencephaly
Definition
a fatal congenital absence of or greatly reduced brain, particularly the cerebrum, resulting from failure of the neural tube to close during organ formation
Term
meningomyelocele
Definition
congenital opening in the spinal cord membranes through which the cord protrudes:  also called spina bifida
Term
trisomy
Definition
three copies of a chromosome instead of the normal 2
Term
Edward's syndrome
Definition
congenital and fatal defect of the fetus (trisomy 18) causing severe multiorgan defects, including mental deficiency
Term
antibody titer
Definition
measure of the amoount of antibody against a particular antigen is present in the blood
Term
hydrops fetalis
Definition
stasis of fluids in tissue spaces, secondary to loss of albumin, leading to a condition in infants of hepatosplenomegaly and respiratory and circulatory destress
Term
kernicterus
Definition
yellow staining of the lipid-rich meninges of the brain and spinal cord due to bilirubin infiltrates
Term
phototherapy
Definition
exposure to sunlight or artificial ultraviolet light for therapeutic purposes, such as treating neonatal hyperbilirubinemia
Term
sensitization
Definition
production of antibody as a response to antigen exposure
Term
glucocorticoids
Definition
adrenal cortical hormones primarily active in protecting against stress and affecting protein and carbohydrate metabolism
Term
surfactant
Definition
a substance that reduces the surface tension of the moist surfaces of solid tissue
Term
alveoli
Definition
sacs at the end of air ducts in the lungs and in contact with capillaries that allow gases to diffuse in or out
Term
pneumocytes
Definition
two types (I and II) of cells that form the alveoli of the lungs
Term
respiratory distress syndrome (RDS)
Definition
severe impairment of respiratory function in a preterm newborn due to immaturity of the enzymatic system essential for pulmonary surfactant production
Term
premature labor
Definition
labor that begins between 20 and 38 weeks' gestation
Term
premature rupture of membranes
Definition
rupture of amniotic membrane prior to the time labor is expected
Term
pre-eclampsia
Definition
a complication of pregnancy characterized by increasing hypertension, proteinuria, and edema
Term
eclampsia
Definition
coma and convulsive seizures of the mother between week 20 of pregnancy and the end of the first week after birth
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