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Clin Pharm Test #2
Summer II 2011
250
Medical
Graduate
07/10/2011

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Cards

Term
First line tx for Dysmenorrhea?
Definition
NSAIDs and Combo OCs
Term
Second line tx for Dysmenorrhea?
Definition
Mefenamic acid, Progestin-containing IUD
Term
Leading cause of absenteeism in women <30y/o?
Definition
pelvic pain occurring around menses
Term
Cause of Epiglottis?
Definition
HiB, strep pyogenes, strep pneumo, staph aureus,
Term
3 y /o pt presents with stridor, labored breathing, dysphagia, drooling, he is anxious and is in the tripod position. What condition do you suspect?
Definition
Epiglottitis
Term
What is the general treatment for epiglottitis?
Definition
Intubate all pts and Admit to ICU
Empiric Anti-microbial therapy
Term
First-line treatment for epiglottitis?
Definition
Cefotaxime or Ceftriaxone or Ampicillin/Sulbactam
Term
Second-line treatment for Epiglottitis?
Definition
Ampicillin and Chloramphenicol
Term
An AA male pt presents with a pustular rash on their chin and jaw line. There are multiple small pustule lesions with an erythematous base and a hair through the center. What condition do you suspect?
Definition
Folliculitis
Term
MC pathogenic cause of Folliculitis?
Definition
Staph Folliculitis
MRSA
Pseudomonal
Term
How is Staph folliculitis treated?
Definition
Mupirocin or Dicloxacilin
Term
Tx for MRSA folliculitis?
Definition
Clindamycin or Bactrim
Term
If folliculitis is severe or persistent, what anti-biotic should you use?
Definition
Cipro or ofloxacin
Term
What are AA male pts particularly susceptible to due to their hair type?
Definition
pseudofolliculitis barbari, folliculitis
Term
Pt c/o bloating and belching with abdominal pain, what condition might you suspect?
Definition
H. pylori (gastritis)
Term
What gastritis condition is usually due to a defective pylorus, protracted exposure to bile or pancreatic juice?
Definition
Reflux
Term
What gastritis condition is described as a stress ulceration or rxn to a hemodynamic d/o?
Definition
Hemorrhagic
Term
What is infectious gastritis commonly due to?
Definition
H pylori
Term
What are the risk factors for gastritis?
Definition
H. pylori
NSAIDs
>60y/o
exposure to alcohol, chemical, drugs
Term
Pt presents with mild epigastric pain, c/o bloating and belching, and urea breath test is positive. What condition do you suspect?
Definition
Infectious gastritis
Term
What is the confirmatory test for gastritis?
Definition
Gastroscopy w/biopsy
Term
First-line tx for gastritis? for H. pylori?
Definition
H2 blocker or PPI
H. Pylori: triple therapy = PPI + Clarithromycin + Metronidazole
Term
Pt presents with urethritis, copious d/c, urinary urgency and frequency as well as dysuria. On further testing you find gram-neg diplococci. What is your first-line tx?
Definition
Ceftriaxone or Cefixime
Term
A pregnant pt presents with gonorrhea, what is the TOC?
Definition
Ceftriaxone
Term
Tx of choice for PID?
Definition
Ceftriaxone + Doxycycline
Term
A 17 y/o male present with c/o a sore throat following a (oral) sexual encounter. How can you confirm it's gonorrhea?
Definition
Gram stain = Gram neg diplococci
Term
What med is contraindicated in pregnancy?
a) Ceftriaxone
b) Erythromycin
c) Tetracycline
Definition
Tetracycline
Term
What med is contraindicated in pregnancy?
a) Ceftriaxone
b) Erythromycin
c) Doxycycline
Definition
Doxycycline
Term
Why is tetracycline contraindicated in children?
Definition
Tetracycline causes discoloration of teeth
Term
What is a dietary contraindication when taking indomethicin?
Definition
Grapefruit
Term
1st line tx for acute gouty attack?
Definition
NSAIDs - Indomethicin
Term
1st line tx for chronic gout?
Definition
Allopurinol (decreases serum uric acid levels)
Term
If pt with chronic gout has renal impairment, what is the 1st line tx?
Definition
Febuxostat (xanthine oxidase inhibitor)
Term
2nd line tx for an acute gouty attack?
Definition
colchicine or triamcinolone (kenalog) or prednisolone
Term
What lab can help identify gout?
Definition
elevated serum uric acid levels
Term
2nd line tx for chronic gout? When should they be used?
Definition
Uricosuric agents (Probenecid or Sulfinpyrazone - Use if refractory/allergic to allopurinol
Term
What supportive care can be given in an acute gouty attack?
Definition
ice packs prn
joint rest
Term
Are cluster HA more predominant in males or females?
Definition
Males
Term
First line tx for Cluster HA acute attack?
Definition
Vasocontrictor - O2 and Zolmitriptan
Term
2nd line tx for Cluster HA acute attack?
Definition
valproic acid
Term
What separates a cluster HA from a migraine?
Definition
Migraines are bilat, have photophobia, aura and throbbing
Cluster HA are unilat, w/out photophobia
Term
What are the SE of Zolmitriptan?
Definition
N/V, worsening HA
Term
A 28y/o male presents to the ER with excruciating unilateral sharp pain that has lasted for approximately 30 min and awoke him from his sleep tonight. This has occurred previously this week, but it lasted for only 20 min and then went away. With the episodes he noticed that his nose ran and his eye watered on the same side as his pain. What condition do you suspect? What is your initial treatment for an acute attack?
Definition
Cluster HA; O2 and zolmitriptan
Term
What is the diagnostic criteria for Cluster HA?
Definition
At least 5 attacks (severe unilateral orbital, supraorbital, or temporal pain lasting 15–180 minutes)
w/one of the following:
Conjunctival injection or lacrimation, eyelid edema
Ipsilateral nasal congestion and/or rhinorrhea
Forehead or facial sweating
Ipsilateral miosis or ptosis
Term
What is the 1st line tx for prophylaxis of a Cluster HA?
Definition
Prednisone or Verapamil
Term
2nd line tx for an acute attack of cluster HA? Adverse effects of this tx?
Definition
Lidocaine 4% intranasally - AE = lightheadedness, nervousness
Term
What is the most accurate test to determine if herpes virus is present in fluid?
Definition
PCR
Term
What are the possible SE from anti-virals used to treat genital herpes?
Definition
Fatigue, Headache, Nausea and vomiting, Rash, Seizures, Tremor
Term
What med can be used in post-herpetic neuralgia to assist with pain management?
Definition
Capsaicin cream
Term
How can you differentiate Chicken pox from a reactivation of herpes zoster?
Definition
herpes zoster follows along a dermatome (can be bilat)
Term
What can be ordered to diagnose herpes zoster reactivation? What will you see?
Definition
Tzank smear, PCR analysis

multinucleated giant cells with intralesional inclusion, lymphatic infiltration of sensory ganglia with focal hemorrhage and nerve cell destruction
Term
What can secondary bacterial infections of herpes zoster reactivation be treated with?
Definition
Silver sulfadiazine topically or systemic antibiotics
Term
What OTC can be used to diminish the burning and itching associated with herpes zoster reactivation?
Definition
Calamine lotion or colloidal oatmeal
Term
What can be used to prevent herpes zoster reactivation? Who should it be used in?
Definition
Vaccine in pts >60y/o
Term
What condition is described as chronic inflammatory dermatosis that primarily affects intertriginous areas?
Definition
HIDRADENITIS SUPPURATIVE
Term
What areas of the body are affected by HIDRADENITIS SUPPURATIVE?
Definition
axillae, groin, peritoneum, and inframammary region
Term
A 26 y/o female pt present with a firm, painful nodule in her groin region. The nodule began as tenderness and itching in her groin. She is currently menstruating. What condition do you suspect? How do treat this condition (in general)?
Definition
HIDRADENITIS SUPPURATIVE; Oral antibiotics
Term
What oral antibiotics are used for hidradenitis suppurative?
Definition
Tetracycline
Doxycycline
Minocycline
Amoxicillin
Term
During Hurley stage 1 of hidradenitis suppurative what is the treatment?
Definition
Topical antibiotic of antibacterial
Term
During Hurley stage 2 or 3 of hidradenitis suppurative what is the treatment?
Definition
Oral antibiotics + topical antibiotics
Term
What general lifestyle changes can help prevent hidradenitis suppurative?
Definition
Smoking cessation
Weight Loss reduces severity
Loose fitting clothing
Cool environments
Term
What can be used to assess the MI risk of a pt?
Definition
Framingham risk factor
Term
What level of total serum cholesterol is considered hypercholesterolemia?
Definition
Serum Cholesterol > 200 mg/dl
Term
What are the cardiac risk factors?
Definition
Smoking
HTN
Age (Men > 45y/o; Women>55y/o)
HDL <40mg/dl
MI or Stroke in 1st degree relative
Term
What lifestyle mods can be used to reduce cholesterol?
Definition
Less fat intake (higher intake of HDL)
Regular Activity
Term
1st line meds for hypercholesterolemia?
Definition
Statins - Fluvastatin, Lovastatin, Pravastatin, Simvastatin, Atorvastatin, Rosuvastatin
Term
What are the contraindications to statin use?
Definition
Active or Chronic Liver Disease
Pregnancy/Breastfeeding
Term
What meds can interact with statins and possibly increase the risk of Myositis?
Definition
Macrolide Antibiotics
Term
2nd line tx for hypercholesterolemia?
Definition
Ezetimibe, Cholestyramine, Colestipol, Colesevelam
Niacin - Increases HDL (Don't use with diabetics)
Gemfibrozil and Fenofibrate (don't use with statins)
Term
What type of monitoring should be done with statin use?
Definition
Monitor lipid panel every 6 - 8 wks until goals are met
Term
What BP is considered Pre-HTN?
Definition
120 - 139 systolic
80 - 89 diastolic
Term
What BP is considered stage 1 HTN?
Definition
140 - 159 systolic
90 - 99 diastolic
Term
What BP is considered stage 2 HTN?
Definition
>160 systolic
>100 diastolic
Term
What is medicine selection when treating HTN based on?
Definition
concomitant conditions and other meds
Term
First line tx for HTN?
Definition
Thiazide diuretics, ACE inhibitors, ARBs, Renin Inhibitor, CCB, B-blockers
Term
What conditions can diuretics worsen?
Definition
gout
Term
In what conditions should beta-blockers not be used?
Definition
Reactive airway dz (asthma, COPD), heart block, bradycardia, diabetes and peripheral vascular dz
Term
In what conditions should diltiazem or verapamil be used with caution in?
Definition
heart failure or heart block
Term
What disease can ACEI worsen?
Definition
bilateral renal vascular disease
Term
How often should a HTN pt be monitored? What labs should be done at least once a year?
Definition
every 3 - 6 mon; U/A, Cr and K
Term
What med can be given to tx influenza? In what populations should this med be given? What is the time frame for giving it?
Definition
Tamiflu; elderly or those at a higher risk of complications; Given if pt has had sx for less than 48hrs
Term
When is f/u with the flu needed?
Definition
Pts with risk factors should follow up in 2-3 days, particularly those with pulmonary diseases
Term
What is the general tx for interstitial cystitis?
Definition
No definitive treatment- pharmacological therapy is aimed at managing sx
Biofeedback bladder training
Term
What meds are used in the tx of interstitial cystitis?
Definition
Oxybutynin (decreases frequency)
Doxepin (decreases frequency)
Term
What conditions are contraindications for oxybutynin use? What conditions should oxybutynin be used with caution?
Definition
CI - Acute angle glaucoma
Used w/caution in - Urinary retention, hepatic/renal impairment, bladder obstruction, GERD, HTN, cardiac dz, hyperthyroidism
Term
What are the contraindications of Doxepin?
Definition
glaucoma, urinary retention, acute recovery MI
(also avoid abrupt withdrawl)
Term
What are the causes of IBS?
Definition
Increased stress, motor abnormalities, visceral hypersensitivity, post-gastroenteritis/infection,
Term
1st line OTC tx for IBS?
Definition
diarrhea - Immodium
constipation - Milk of Magnesia/Metamucil etc
Term
What home remedies can be used in the tx of IBS?
Definition
peppermint, herbs, acupuncture, hypnosis etc
Term
Tx for diarrheal IBS?
Definition
Loperamide or SSRIs (ex. Alosetron)
Term
What is the treatment for constipation IBS?
Definition
Methscopolamine (anti-cholinergics)
Milk of Magnesia (Osmotic laxatives)
Lubiprostone
Term
What are most cases of laryngitis associated with?
Definition
viral URI
Term
What condition is described as inflammation, erythema and edema of the mucosa of the larynx and/or vocal cords?
Definition
Laryngitis
Term
Pt presents with hoarseness, that began with throat tickling, fever, dysphagia and mild cough. What condition do you suspect?
Definition
Laryngitis
Term
What are some underlying causes of pharyngitis?
Definition
Viral infections
misuse or abuse of voice
bacterial infections (rare)
fungal infections (rare)
inhaling irritating substances
aspiration of caustic chemicals
GERD
inhaled steroids (such as those used in asthma tx)
vocal cord nodules
retropharyngeal abscess
neuromuscular d/o (ex. myasthenia gravis)
2ndary Syphillis left untreated
leprosy
laryngeal TB
Term
What is the general treatment for an uncomplicated acute case of laryngitis?
Definition
usually self-limiting, vocal rest, avoid smoking and alcohol, use cool mist humidifier, increase fluid intake, use steam inhalations
Term
What are the 1st line tx for laryngitis?
Definition
Analgesics, antipyretics and cough suppressants
Term
What are the 2nd line tx for laryngitis?
Definition
inhaled corticosteroids (allergy induced)
PPI (GERD)
Fluconazole (candidal laryngitis)
Term
What are some CAM tx for laryngitis?
Definition
Echinacea, eucalyptus, hot lemon and honey tea, vitamin C and zinc
Term
What is the MCC of laryngotracheobronchitis?
Definition
Croup is MC caused by viral respiratory infection (parainfluenza is MC pathogen, adenovirus, RSV and rhinovirus)
Term
What imaging can be done to verify a dx of laryngotracheobronchitis? What do they show?
Definition
PA and lateral neck X-ray; show "steeple", "hourglass" or "pencil point" sign
Term
Is mild laryngotracheobronchitis an inpatient or outpatient?
Definition
outpt
Term
Main general tx for mild croup?
Definition
Keep child calm (limit amt of tests and procedures)
Cool dry air helps open airway
Fluid intake increased
Term
1st line tx for croup?
Definition
Nebulized epinephrine (0.05ml/kg/dose) and dexamethasone (IM usually)
Term
When should a croup pt be admitted?
Definition
If signs of respiratory distress
Term
What is the best way to prevent the transmission of croup?
Definition
Wash hands
Parainfluenza vaccination
Term
What is the mainstay tx for low back pain?
Definition
NSAIDs (Ibuprofen)
Term
What meds can be used in the tx of low back pain after NSAIDs?
Definition
Muscle relaxants
Opioid Analgesics (can be considered)
Steroids
Term
What are the SE of Opioids?
Definition
dependance
sedation
constipation
decreased rxn time
nausea
cloudy judgement
Term
In what type of low back pain would steroids be most useful?
Definition
Sciatica
Term
What pathogen causes Lyme disease?
Definition
Borrelia burgdorferi
Term
What is the vector for borrelia burgdorferi?
Definition
ticks - MC tickborne infection in the US and Europe
Term
What are the S & S of a disseminated Lyme infection?
Definition
facial palsies, joint pain, orchitis, hepatitis, iritis, pericarditis, > 1 organ involvement
Term
What is the 1st line tx for Erythema migrans?
Definition
Doxycycline (CI in pregnant or breastfeeding females and children)
Amoxicillin
Term
When should a pt with lyme disease be admitted?
Definition
When infection has complications such as carditis or meningitis
Term
2nd line tx for Lyme disease?
Definition
Erythromycin
Term
If a pregnant pt presents with erythema migrans, what should the tx be?
Definition
Parenteral Amoxicillin or Erythromycin
Term
What is the MC complication of acute otitis media?
Definition
Acute Mastoiditis
Term
What is chronic mastoiditis usually associated with?
Definition
cholesteatoma or chronic ear dz
Term
If acute otitis media persist for more then 2 weeks, what should you suspect?
Definition
Mastoiditis
Term
What imaging is characteristic of mastoiditis?
Definition
clouding of mastoid air cells or coalescence of air cells
Term
What are the MC pathogens causing mastoiditis?
Definition
Strep pneumo
Strep pyogenes
Grp A B-Strep
Staph aureus
M catarrhalis
H influenza
Pseudomonas aeruginosa (becoming more prevalent)
Term
What is the general tx for mastoiditis?
Definition
admit, IV antibiotics, ENT referral
Term
What is the general tx for mastoiditis?
Definition
admit, IV antibiotics, ENT referral
Term
1st line tx for acute Mastoiditis?
Definition
IV 3rd generation Cephalosporin (Rocephin)
Term
1st line tx for chronic mastoiditis?
Definition
Ofloxacin otic solution
Term
If mastoiditis is chronic or unresponsive to antibiotic tx, what should be suspected? How should it be treated?
Definition
Psuedomonas inf; Tx with Zosyn piperacillin/tazobactam
Term
When are the precautions of use of Rocephin in adults?
Definition
Adjust dose if renal impairment is present
Term
What must be monitored with Zosyn?
Definition
baseline and periodic monitoring of CBCs and LFTs
Term
2nd line drug for mastoiditis?
Definition
Clindamycin
Term
What is a complication of using Clindamycin?
Definition
may cause C. difficile
Term
17y/o pt presents with fever, HA, nuchal rigidity, altered mental status, petechiae or purpuric rash, and Kernig's/Brudzinski's sign. What condition do you suspect?
Definition
Bacterial Meningitis
Term
Pt presents with fever, nuchal rigidity, altered mental status. What condition do you suspect?
Definition
Viral Meningitis
Term
Which is more life threatening, viral or bacterial meningitis? How can you differentiate between the two?
Definition
Bacterial (true emergency); CSF fluid analysis
Term
What are the MC bacterial pathogens causing bacterial meningitis?
Definition
H. influenza, N. meningitidis, S. pneumo
Term
Treatment for bacterial versus viral meningitis?
Definition
Bacterial - Antibiotics
Viral - Supportive tx
Term
What condition is described as excessive menstrual flow?
Definition
Menorrhagia
Term
What are some causes of menorrhagia?
Definition
Hypothyroidism
Endometrial proliferation/excess/hyperplasia
local factors (abnormal hormone levels, polyps, fibroids)
Coagulation d/o
Term
First-line med should be used for control of acute menorrhagia with SEVERE bleeding?
Definition
Premarin
Term
First-line med for acute control of LESS severe bleeding from menorrhagia?
Definition
Provera
Term
First-line med to PREVENT heavy bleeding in subsequent cycles?
Definition
Provera
Term
Second-line meds for menorrhagia?
Definition
Naproxen, Mefenamic acid, ibuprofen (Non-steroidal prostaglandin-synthetase inhibitors)
Term
When should imaging be performed with a migraine type complaint?
Definition
- New onset in pt over 50y/o
- Change in HA pattern
- Atypical pattern of sx
- Prolonged or bizzarre aura
Term
1st line tx for mild to moderate migraine?
Definition
combo of acetaminophen, ASA and caffeine
OR 5-HT-1 agonists (triptans)
Term
DOC in status migrainous?
Definition
Ergotamines (Dihydroergotamine)
Term
Contraindications to 5-HT-1 agonist?
Definition
Coronary heart disease, peripheral vascular disease, uncontrolled HTN, complex migraine
SHOULD NOT be used within 24hrs of ergot derivative or other triptans
Term
2nd-line tx of severe migraine?
Definition
Shorter-acting opioids
Term
What pathogen causes Molluscum Contagiosum?
Definition
Poxviridae
Term
Pt presents with c/o a rash that developed afer her son had a similar one. The rash is located on her left forearm and shoulder. The rash is made of flesh colored, pearly, dome-shaped papules with central umbilication. What condition do you suspect?
Definition
Molluscum Contagiosum
Term
First-line meds for mulluscum contagiosum?
Definition
Cantharidin, Cimetidine, Imiquimod
Term
When is Imiquimod cream contraindicated?
Definition
Pregnancy
Term
What surgical or other procedures can be used in the tx of mulluscum contagiosum?
Definition
Cryotherapy
Currettage
Incision & expression of central particle
Term
What pathogen causes Mono?
Definition
EBV
Term
What is the "classic triad" of Mono sx?
Definition
malaise, HA, low-grade fever
Term
When should you admit a Mono pt?
Definition
If airway obstruction or splenic rupture
Term
When should imaging be used in mono?
Definition
U/S to confirm splenomegaly
CT if splenic rupture is suspected
Term
What is the prognosis of mono?
Definition
S & S will last for months
Term
1st line tx for Mono?
Definition
Acetaminophen
NSAIDs
Lozenges
Gargling with 2% lidocaine solution
Term
First-line tx for motion sickness?
Definition
Dimenhydrinate (Dramamine)
Meclizine (Antivert)
Cyclizine (Marezine)
Term
What is the dosage for Dimenhydrinate (Dramamine) in children 6 - 12y/o?
Definition
25 - 50 mg q 6 - 8 h.
Term
What SE can anti-histamines cause in kids?
Definition
excess excitation
Term
When is the peak incidence of motion sickness in children? When is it rarest?
Definition
Peak = 3 - 12 y/o
Rarest = <2y/o
Term
What SE are more common in elderly with tx of motion sickness?
Definition
anticholinergic SE
Term
What motion sickness meds are safe to use in pregnancy?
Definition
Meclizine
Dimenhydrinate
Term
What are the risk factors for MI?
Definition
Increasing age
HTN
Tobacco/alcohol/drug abuse
DM
family hx
dyslipidemia
early CAD
sedentary lifestyle
Term
What monitoring must be done if an MI is suspected?
Definition
Continuous EKG
Term
During pregnancy labs and monitoring that can mimic an MI include?
Definition
ST depression
Increased CK-MB
Mild increase in troponin I
Term
When does Troponin rise after MI? How long does it remain elevated?
Definition
Rises - 3 to 6 hrs after MI onset
Lasts - 7 to 10 days
Term
When does CK-MB rise following an MI? How long does it remain elevated?
Definition
Rise - 3 to 4 hrs after onset
Last - 2 to 3 days
Term
What is myoglobin a marker for?
Definition
myocardial necrosis
Term
When does myoglobin rise after an MI? How long does it stay elevated?
Definition
Rises - 2 hrs after MI
Lasts - 24 hours
Term
Following an MI, what is the O2 sat goal?
Definition
> 90%
Term
If pt has been given 3 doses of nitro for their MI sx and still has pain, what should be done?
Definition
IV nitro
Term
What med should be given for a STEMI?
Definition
thienopyridine (anti-platelet agent)
Term
What is the prevalence of obesity in the US?
Definition
32.2%
Term
What BMI is considered class I obesity?
Definition
BMI = 30 to 35
Term
What BMI is considered class 2 obesity?
Definition
BMI = 35 to 40
Term
What BMI is considered class 3 obesity (morbid obesity)?
Definition
BMI > 40
Term
When should meds for obesity be considered?
Definition
consider after 6 mon of general conservative tx
Term
What BMI qualifies for surgical measures?
Definition
BMI > 40
OR BMI > 35 w/ comorbidities
Term
First-line tx for weight loss?
Definition
Orlistat
Term
With what med should the concomitant use of Orlistat be cautioned with? Why?
Definition
Metformin - Increases risk of developing lactic acidosis
Term
What are the contraindications to Orlistat use?
Definition
Breastfeeding
Chronic malabsorption syndrome
Cholestasis
Anorexia
Bulimia
Term
What meds does Orlistat interact with?
Definition
Cyclosporin
Warfarin
Term
What is the 2nd line tx for weight loss?
Definition
Phentermine (Adipex-P)
Term
What conditions are contraindicated with Phentermine?
Definition
Pregnancy
breastfeeding
CVD
arteriosclerosis
mod-sev HTN
glaucoma
hx of drug abuse
Term
What meds are contraindicated with Phentermine?
Definition
MAOIs w/in 14 days
Sibutramine
Anorexiants
Stimulants
Term
What meds are contraindicated with Phentermine?
Definition
MAOIs w/in 14 days
Sibutramine
Anorexiants
Stimulants
Term
What are some precautions when using Phentermine?
Definition
Do not w/drawl abruptly
Term
In which pts is use of Phentermine cautioned?
Definition
Elderly
DM
HTN
Term
With weight loss meds, when should you f/u?
Definition
f/u within 4 weeks
Term
When should meds be used for weight loss?
Definition
After 6 mon of diet and exercise has failed
Term
What condition is described as a chronic fungal infection of the fingernails or toenails?
Definition
Onychomycosis
Term
What are the risk factors for onychomycosis?
Definition
Older age
Tinea pedis
CA
DM
Peripheral Vascular Dz
Psoriasis
Cohabitation with others who have onychomycosis
Immunodeficiency
Swimming
Smoking
Term
With what labs can onychomycosis be confirmed?
Definition
KOH prep of nail clippings
Histologic exam of nail clippings
Term
With the tx for onychomycosis, what labs must you do to monitor the SE of the anti-fungals?
Definition
LFTs and CBC
Term
If onychomycosis is on the dominant hand only, what is the most likely pathogen?
Definition
Candidal
Term
Which type of pathogen causes onychomycosis that involves more than one infected site?
Definition
Dermatophytes
Term
What is the MC pathogen causing onychomycosis in people older than 60y/o?
Definition
Molds
Term
What med is used to tx onychomycosis?
Definition
Terbinafine OR Itraconazole
Term
What are the contraindications for using oral anti-fungals?
Definition
Hepatic Dz
Pregnancy
current CHF or Hx of CHF
Porphyria
Term
What imaging is best for viewing Osgood-Schlatter Dz? What will you see on the imaging studies?
Definition
Lateral Knee Radiographs - prominent tuberocity, separation of ossicles or calcification
Term
What is the tx for Osgood-Schlatter's dz?
Definition
RICE, NSAIDs, PT (can improve stability and flexibility and prevent reoccurrences)
Term
What are the causes of osteoporosis?
Definition
Aging and Hypoestrogenemia
Term
What are the NON-modifiable risk factors for osteoporosis?
Definition
Advanced age (>65y/o)
Female gender
Caucasian or Asian ethnicity
Fam Hx of osteoporosis
Hx of atraumatic fx
Term
What are the modifiable risk factors for osteoporosis?
Definition
Low body wt
Ca or Vit D Def
Inadequate physical activity
Cigarette Smoking
Excessive alcohol intake
Meds (Corticosteroids, Thyroid Hormone Replacement, medroxyprogesterone acetate, heparin)
Term
What is the gold standard for measuring bone mineral density?
Definition
DEXA scan - radiograph of the lumbar spine/hip
Term
1st tx for osteoporosis?
Definition
Bisphosphonates (Alendronate)
Term
2nd line tx for osteoporosis?
Definition
Raloxifene (Selective Estrogen Receptor Modulator)
Term
When should a pt with osteoporosis be referred to Endo?
Definition
If pt experiences recurrent bone loss refractory to tx or fractures
Term
What are the risk factors for necrotizing otitis externa in adults?
Definition
Advanced Age
DM
Debilitating Dz
AIDs
Term
What are the risk factors for necrotizing otitis externa in children?
Definition
Leukopenia
Malnutrition
DM
DI
Term
What is the tx for necrotizing otitis media?
Definition
Admit, Parenteral antipseudomonal antibiotics
Term
What is the tx for OE resistant to meds?
Definition
Surgical intervention
Term
What is the MC cause for childhood visits to a physician?
Definition
OM
Term
What is the MC bacterial pathogen in OM?
Definition
Strep Pneumo
Term
Why are children more susceptible to OM than adults?
Definition
ET dysfunction
Term
What med is first-line for OM treatment in pts >3mo old?
Definition
Amoxicillin or Amoxicillin/clavulanate
Term
What med is first-line for OM treatment in pts >6mo old?
Definition
Cefdinir
Term
If pt has symptoms of OM after 48 - 72 hrs of tx, what should be done?
Definition
switch to broad spectrum antibiotic
Term
If the child's TM is ruptured with OM, what pt instructions should be given?
Definition
Avoid swimming
Term
What are the serious complications of OM?
Definition
Mastoiditis (MC complication)
Meningitis
Brain Abscess
Term
MCC of ACUTE paronchia?
Definition
S. Aureus
Term
MCC of CHRONIC paronchia?
Definition
C. albicans
Term
Risk factors for paronchia?
Definition
Diabetic and Immunocompromised pt
Term
A 40 y/o diabetic pt presents with a sore on her toe. It is painful, erythematous and edematous. The sore is located on her 3rd digit around the edge of the nailbed. Pus is present. What condition do you suspect?
Definition
Paronchia
Term
What is the DOC for Paronchia?
Definition
Augmentin
Term
What pathogen is commonly associated with chronic paronchia? What med should be used to treat it?
Definition
Primarily fungal, tx with topical miconazole and add oral anti-fungal if needed
Term
A 18y/o male presents with fever and difficulty swallowing and talking . On PE you note a collection of pus between the anterior and posterior tonsillar pillars and the superior pharyngeal constrictor muscles. What condition do you suspect?
Definition
Peritonsillar abscess
Term
What usually precedes a peritonsillar abscess?
Definition
Pharyngitis or tonsillitis
Term
1st line tx for Peritonsillar abscess?
Definition
PCN
Term
If pt is allergic to PCN, what is the 1st line tx for peritonsillar abscess?
Definition
Erythromycin or Cephalexin
Term
MCC of pharyngitis?
Definition
acute viral infection
Term
What is the common cause of chronic pharyngitis?
Definition
Most likely non-infectious, instead a result of post-nasal d/c of chronic allergic rhinitis or reflux
Term
What bacterial pathogens are MC responsible for acute pharyngitis?
Definition
Grp A B-menolytic Strep
N. gonorrhoeae
C. Diptheria
Term
What viral pathogens are MC responsible for acute pharyngitis?
Definition
Rhinovirus
Adenovirus
Parainfluenza virus
Term
1st line tx for pharyngitis?
Definition
Usually viral so supportive
If bacterial PCN or Amoxicillin
Term
A pt with a sore throat, hoarseness, swollen lymphnodes, erythematous pharynx presents back to your after tx with Amoxicillin. She came to you b/c she now has a rash. What pathogen might be causing her sore throat and new rash?
Definition
EBV - if Amoxicillin is used to tx, can cause rash
Term
What is the BEST treatment for pharyngitis if a rapid strep test is pos? Why?
Definition
PCN - only treatment proven to prevent rheumatic fever
Term
If pt with pharyngitis has PCN allergies, what is the first-line treatment?
Definition
Erythromycin OR Cephalexin
Term
What test can be done to confirm your suspicion of pinworms? Describe positive results.
Definition
Adhesive tape test - pos if on microscopy ova are present on tape
Term
first-line tx for Pinworms?
Definition
Pyrantel Pamoate (Pin-X)
Term
second-line tx for pinworms?
Definition
Mebendazole (Verox)
Term
What is the DOC for pneumonia?
Definition
Azithromycin, Clarithromycin, Erythromycin
Term
In which sex is pneumonia MC?
Definition
Men
Term
When is CAP most common?
Definition
Winter months
Term
What condition is described as an acute or chronic inflammation of the rectum?
Definition
Proctitis
Term
What are the risk factors for the development of proctitis?
Definition
Anal Intercourse
Pelvic radiation
Rectal Injury
Rectal med use
Jewish descent
Term
What are the infectious causes of proctitis?
Definition
Gonorrhea/Chlamydia
Syphillis
HSV2
LGV
Chancroid
CMV
HPV
Term
If proctitis is caused by gonorrhea, what med is used to treat it? If allergy to first choice, what should be used?
Definition
Ceftriaxone (if allergy use azithromycin)
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