Term
Muscarinic M1 Cholinergic Receptor's Typical Location
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Definition
CNS neurons, some presynaptic sites
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Term
Muscarinic M2 Cholinergic Receptor's Typical Location
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Definition
Myocardium, smooth muscle
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Term
Muscarinic M3 Cholinergic Receptor's Typical Location
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Definition
Exocrine glands, vessels (smooth muscle and endothelium)
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Term
Muscarinic M4 Cholinergic Receptor's Typical Location
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Definition
CNS neurons, vagal nerve ending
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Term
Muscarinic M5 Cholinergic Receptor's Typical Location
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Definition
Vascular endothelium, especially cerebral vessels; CNS neurons
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Term
Nicotinic Nn Cholinergic Receptor's
Typical Location
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Definition
Postganglionic neurons, some presynaptic cholinergic terminals
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Term
Nicotinic Nm Cholinergic Receptor's
Typical Location
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Definition
Skeltal muscle neuromuscular end plates
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Term
Muscarinic M1 Cholinergic Receptor's
Result of Ligand Binding |
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Definition
| Formation of IP3 and DAG, Increased intracellular Ca+2 |
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Term
Muscarinic M2 Cholinergic Receptor's
Result of Ligand Binding |
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Definition
| Inhibition of adenylate cyclase, opening K+ channels |
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Term
Muscarinic M3 Cholinergic Receptor's
Result of Ligand Binding |
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Definition
| Like M1 Ligand Binding: Formation of IP3 and DAG, Increased intracellular Ca+2 |
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Term
Muscarinic M4 Cholinergic Receptor's
Result of Ligand Binding |
|
Definition
| Like M2 Ligand Binding: Inhibition of adenylate cyclase, opening K+ channels |
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|
Term
Muscarinic M5 Cholinergic Receptor's
Result of Ligand Binding |
|
Definition
| Like M1 Ligand Binding: Formation of IP3 and DAG, Increased intracellular Ca+2 |
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Term
Nicotinic Nn Cholinergic Receptor's
Result of Ligand Binding |
|
Definition
| Opening of Na+, K+ channels, depolarization |
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Term
Nicotinic Nm Cholinergic Receptor's
Result of Ligand Binding |
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Definition
| Opening of Na+, K+ channels, depolarization |
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