Term
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Definition
Muscarinic antagonist
used preoperatively to reduce secretions
antidote to treat excess acetylcholine |
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Term
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Definition
Muscarinic antagonist
used preoperatively to reduce secretions
as a patch, used to prevent motion sickness
acts mainly in the CNS |
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Term
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Definition
Muscarinic antagonist
used preoperatively to reduce secretions |
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Term
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Definition
| Muscarinic antagonist used to produce bronchial dilation in COPD esp in older people bc B2 receptors (albuterol's) decreased in older people. Albuterol preferable usually because it works faster |
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Term
| Effects of antimuscarinics on eye and respiratory |
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Definition
mydriasis AND cycloplegia (inability to focus bc inhibition of accommodation)
bronchodilation and decreased secretions |
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Term
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Definition
| Class is Xanthines which Bronchodilate via inhibition of a Phosphodiesterase. This keeps cAMP up and smooth muscle relaxed |
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Term
| How to treat atropine overdose? |
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Definition
| 1) Treat symptomatically 2) Provide cholinesterase inhibitor, e.g., physostigmine, in small doses 3) Blankets and diazepam for seizure control |
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Term
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Definition
Ganglionic blocker-interferes with the postsynaptic action of ACh at the nicotinic receptor of all autonomic ganglia
Limited clinical use-treat hypertension during surgery |
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Term
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Definition
Ganglionic blocker-interferes with the postsynaptic action of ACh at the nicotinic receptor of all autonomic ganglia.
Limited clinical use-treat hypertension during surgery |
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Term
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Definition
reversible
depolarizing NMJ blocker
used to relax muscles during surgery
Terminate effects by supporting patient and waiting
Half life under 1 min |
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Term
d-tubocurarine
pancuronium
atracurium |
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Definition
Nondepolarizing NMJ blocker (competitive antagonist)
produces skeletal muscle relaxation for surgery
Caution-Respiratory paralysis. If mechanical ventilation is not provided, the patient will asphyxiate
Bring patient off these by using ACh esterase inhibitor+muscarinic antagonist (to avoid lowering HR) |
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Term
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Definition
Nondepolarizing NMJ blocker (competitive antagonist)
produces skeletal muscle relaxation for surgery
Caution-Respiratory paralysis. If mechanical ventilation is not provided, the patient will asphyxiate
Bring patient off these by using ACh esterase inhibitor+muscarinic antagonist (to avoid lowering HR) |
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Term
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Definition
| Treats malignant hyperthermia (blocks Ca++ release from sarcoplasmic retic, preventing heat-generating contractions in response to inhalational anesthetics like halothane |
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Term
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Definition
Prevents release of acetylcholine
treats cervical dystonia, neck pain, focal dystonia, cosmetic |
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