Immature liver and kidney functions

Immature blood brain barrier (careful of drugs affecting CNS-ie barbituates)

Decreased gastric acid production (inc pH)

slower gastric emptying time

Decreased first-pass medication metabolism

Increased absorption of topical meds

Lower BP (dec distribution)

Higher body weight content (dilution effect)

decreased serum protein binding sites (dec protein)

1.  Respiratory

2.  Anti-bacterials (Systemic)

3. Dermatologic

1.  Dec gastric acidity (Inc alkalinity)

2.  Dec GI motility and empyting time

3.  Decreased bf to heart, liver, and kidney

4.  Dec hepatic enzy fx.

5. Decreased GFR (kid fx)

6.  Decreased protein binding sites (imp b/c if taking a drug that is highly prot bound then u will have lots of unbound protein and more toxic effect

7.  decreased body water

8. dec lean body mass
5. 

Ginseng is used to:

It mimics what neurotransmitter:

1.  Relieve stress, enhance immune system, and decrease fatigue

2.  Mimics epinephrine---vasoconstrictor and is a sympathomimetic