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Chapter9
blood and lymphatic system
108
Medical
Undergraduate 1
02/21/2013

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Term
Acquired immunity
Definition
is a result of the body developing the ability to defend itself against a specific agent as a result of having had the disesase of from having recieved an immunization against a disease.
Term
Acquired immunodeficiency (AIDS)
Definition
involves clinical conditions that destroy the body's immune system in the last or final phase of a human immunodeficiency virus infection.
Term
Adenoids
Definition
masses of lymphatic tissue located near the opening of the nasal cavity.
Term
aggultination
Definition
The clumping of cells as a result of interaction with specific antibodies called aggulutinins
Term
Albumin
Definition
A plasma protien . Various are found in partically all medical tissues and in many plant tissues.
Term
Allergen
Definition
A substance that can produce a hypersensitive reaction in the body.
Term
Allergy
Definition
A hypersensitive reaction to normally harmless antigens. Most of wich aree enviromental.
Term
Anaphylaxis
Definition
An exaggerated , life threatning hypersenistivity reaction to a previously encounted antigen.
Term
Anemia
Definition
A condition in which there is a decrease in hemoglobin in the blood to levels below the normal range , resulting in a deficiency of oxygen being delivered to the cells .
Term
Anisocytosis
Definition
An abnormal condition of the blood characterized by red blood cells of variable and abnormal size.
Term
Anitbodies
Definition
Substances produced by the body in response to bacteria, viruses,or other foreign substances . Each class of antibody is named for its action.
Term
Antigens
Definition
A substance , usually a protein that causes the formation of an antibody and reacts specifically with that antibody
Term
Aplastic Anemia
Definition
Severe anemia due to destruction or depressed functioning of the bone marrow, usually resulting from bone cancer , radiation, or the toxic effect of certain drugs or chemicals.
Term
Ascites
Definition
An abnormal collection of fluid within the peritoneal cavity.
Term
Basophil
Definition
A granulocytic white blood cell characterized by cytoplasmic granules that stain blue when exposed to a basic dye . represents 1% or less of the total white blood cell count.
Term
Bilirubin
Definition
The orange-yellow pigment of bile formed principally by the break down of hemoglobin in red blood cells after termination of their normal life span.
Term
Blastocyte
Definition
An undifferentiated blastomere of the morula or the blastula stage og an embryo.
Term
Chromophilic
Definition
cell,tissue,or substance
Term
Coagulation
Definition
The process of transfoming a liquid into a solid , especially of the blood .
Term
Corpuscle
Definition
Any cell of he body; a red or white blood cell.
Term
Cytogenesis
Definition
Origin and developement of cells.
Term
Cytomegalovirus
Definition
A large species- specific herpes type virus with a wide variety of dises effects cause serious illness in persons with AIDS and newborns.
Term
Differentiation
Definition
A process of developement in which unspcialized cells or tissues are systemically modified and altered to achieve specific and characteristic physical forms.
Term
Direct antiglobulin test
Definition
USED to discover the presence of antierythrocyte antibodies present in the blood of an RH negative women.
Term
Dycrasia
Definition
Abnomal condition of the blood of the bone marrow, such as leukemia , aplastic anemia or parental RH incompatibility.
Term
Edema
Definition
The abnormal accumilation of fluid in interstitial spaces of tissue.
Term
electrophoresis
Definition
Movement of charged suspended particles through a liquid medium in respeonse to changes in an electric field . Charged particles of a substance migrate in a specific direction at a specific speed.
Term
Enzyme
Definition
Linked immunosorbent assay.
Term
Eosinophil
Definition
Agranulocytic , bilobed leukocyte somewhat larger than a neutrophil characterized by large numbers of coarse, refractile , cytoplasmic granules that stain with the acid dye eosin.
Term
Eosinophilia
Definition
Presence of an abnormally increased number of eosinophils in the blood.
Term
Erythermia
Definition
An abnormal increase in the number of red blood cells.
Term
Erythroblast
Definition
An immature red blood cell
Term
Erythrocyte
Definition
A mature blood cell.
Term
Erythrocyte Sedimentation Rate
Definition
Test performed on the blood , which measures the rate at which red blood cells settle out in a tube of unclotted blood. Determined by measuring the settling distance of RBC's is normal saline over one hour.
Term
Erythrocytosis
Definition
Also known as polycythemia vera is a myeloproliferative disorder characterized as an elevated level of blood cells (red).
Term
Erythropoiesis
Definition
The process of red blood cell production.
Term
Erythropoietin
Definition
A hormone synthesized mainly in the kidneys and released into the bloodstream in response to anoxia (lack of oxygen). Hormone acts to stimulate and regulate the production of erythrocytes thus increase the oxygen . Carrying capacity of the blood.
Term
Fibrin
Definition
A stringy , insoluable protien that is the substance of a blood clot.
Term
Fibrinogen
Definition
A plasma protien converted into fibrin by thrombin in the presense of calcium ions.
Term
Globin
Definition
Group of 4 globulin protien molecules that become bound by the iron in heme molecules to form hemoglobin.
Term
Globulin
Definition
A plasma protien made in the liver. Globulin helps in the synthesis of antibodies.
Term
Granulocytes
Definition
A type of leukocyte characterized by the presence of cytoplasmic granules.
Term
Granulocytosis
Definition
Condition characterized by an abnormally large number of granulocytes in blood or tissue.
Term
Hematocrit
Definition
Centrifuge for seperating blood cells from plasma
Term
Hematologist
Definition
One who specializes in diseases and disorders of blood and blood-forming tissues.
Term
Hematology
Definition
Scientific study of blood and blood-forming tissues.
Term
Heme
Definition
Pigmented iron containing , nonprotien proportion of the hemoglobin molecule . Heme binds with and carries oxygen in the blood cells, releasing it to tissues that give off excess amounts of carbon dioxide.
Term
Hemochromatosis
Definition
Rare metabollic disorder characterized by a bronzed skin, cirrhosis, and sever diabetes, caused by the deposit in tissue especially of the liver.
Term
Hemoglobin
Definition
Complex protien - iron compound in the blood that carries oxygen to the cells from the lungs and carbon dioxide away from the cells to the lungs.
Term
Hemogram
Definition
Graphic record of the cellular elements of the blood.
Term
Hemolysis
Definition
Breaking down of red blood cells with liberation of hemoglobin.
Term
Hemolytic
Definition
Same as hemolysis
Term
Hemophilia
Definition
X-linked genetic disorders , symptomatic chiefly in males , in which excessive bleeding occurs owing to the absence or abnormality of a clotting factor in the blood .
Term
Hemorrhage
Definition
loss of a large amount of blood in a short period of time , either externally or internally hemmorhage may be arterial , venous, or capillary .
Term
Hemostasis
Definition
Termination of bleeding by mechanical or chemical means or by the complex coagulation process of the body , consistion of vasoconstriction , platelet aggregation , and thrombin and fibrin synthesis.
Term
Heparin
Definition
A naturally occuring anticlotting factor present in the body.
Term
Hyperalbuminemia
Definition
Greater than normal amounts of the bile pigment , bilirubin, in the blood.
Term
hyperlipemia
Definition
Excessive level of blood fats , usually caused by a lipoprotien lipase deficiency or a defect in the conversion of low density lipoprotiens to high - density lipoprotiens called hyperlipdemia.
Term
Hyperlipidemia
Definition
also called hyperlipemia.
Term
Hypersensitivity
Definition
Excessively sensative.
Term
Hypersplenism
Definition
Abnormal condition characterized by an enlarged spleen that prematurely destroys red blood cells or platelets.
Term
Immune
Definition
Pertaining to the production of antibodies or lymphocytes that can react with a specific antigen.
Term
Immunity
Definition
State of being resistant to or protected from a disease . The individual is said to be immune.
Term
Immunization
Definition
Process of creating immmmunity to a specific disease.
Term
Immunodeficiency
Definition
Impairment of the immune response , predisposing to infection and certain malignants.
Term
Immunologist
Definition
Health specialist whose training and experience is concentrated in immunology.
Term
Immunology
Definition
Study of the reaction of tissues of the immune system of the body to antigenic stimulation.
Term
Immunotherapy
Definition
Special treatment of allergic responses that administers increasingly large doses of the offending allergens to gradually develop immunity.
Term
Isotonic
Definition
Pertaining to a solution containing the same salt concentration as mammalians blood (humans).
Term
Kaposi's Sarcoma
Definition
Locally destructive malignant neoplasm of the blood vessels associated with AIDS, typically forming lesions on the skin , visceral organs , or mucous membranes.
Term
Karyocyte
Definition
Immature normoblast
Term
Leukemia
Definition
Several cancers of the bone marrow that prevent the normal manufature of red and white blood cells and platelets.
Term
Leukocyte
Definition
A white blood cell, one of the formed elements of the circulating blood system.
Term
Leukocytopenia
Definition
Abnormal decrease in muber of white blood cells to fewer than 5,000 cells per cubic milimeter.
Term
Lymph
Definition
Interstitial fluid picked up by the lymphatic capillaries and eventually returned to the blood . Once the interstitial fluid enters the lymphatic vessles, it is known as lymph.
Term
Lymphadenitis
Definition
Inflammation in the lymphatic gland.
Term
Lymphadenopathy
Definition
Any disorder of the lymph nodes or lymoh vessels , characterized by localized or generalized enlargement.
Term
Lymphaniogram
Definition
X-ray assesment of the lymphatic system following injection of a contrast medium into the lymph vessels in the hand or foot.
Term
Lymphocyte
Definition
Small, agranulocytic leukocytes originating from fetal stem cells and developing in the bone marrow.
Term
Lymphoma
Definition
Tumor arising from any of the cellular elements of lymph nodes.
Term
Macrophage
Definition
Any phagocytic cells involved in the defense against infection and in the disposal of the products of the breakdown of cells. Found in the lymph nodes , liver, spleen, lungs, brain,and spinal cord.
Term
Megakaryocyte
Definition
Large bone - marrow cell having a lobulate nucleus , regarded as the source of blood platelets.
Term
Monocyte
Definition
A large mononuclear leukocyte.
Term
Monocytopenia
Definition
Abnormally low number of monocytes in the blood.
Term
Mononucleosis
Definition
Presence of an abnormally large number of mononuclear leukocytes , or monocytes in the blood ; (infectios mononucleosis).
Term
Morphology
Definition
Branch of biology dealing with the form and structure of organisms.
Term
Multiple Myeloma
Definition
A malignant plasma cell tumor of the bone marrow that destroys bone tissue.
Term
Myasthenia Gravis
Definition
Disease of impaired transmission of motor nerve impulses characterized by episodic muscle weakness and easy fatigibility especially of the face, tongue and neck.
Term
Myeloblast
Definition
An immature myelocyte.
Term
Myeloid
Definition
Pertaining to the bone marrown or the spinal cord.
Term
Natural Immunity
Definition
Individual who has a full-blown case of a disease such as measels will usually develop enough antibodies to prevent a recurrece of the disease.
Term
Neutrophil
Definition
A polymorphonuclear granular leukocyte that stains easily with neutral dyes.
Term
Pancytopenia
Definition
Marked reduction in the number of the red blood cells ,white blood cells and platelets.
Term
Pathogens
Definition
Any disease - producing agent , escpecially a virus, bacterium , or other microorganisms .
Term
Pernicious Anemia
Definition
Sever anemia caused by the diminution or absence of stomach acid secretion , with consequent failure of the gastric mucosa.
Term
Phagocyte
Definition
Any cell , as a macrophage , that ingests and destroys foreign particles , bacteria and cell debi's.
Term
Phagocytosis
Definition
Injestion of a samller cell or cell fragment , a microorganism , or foreign particles by means of the local infolding of a cells membrane.
Term
Plasma
Definition
Watery , straw -colored , fluid portion of the lymph and the blood in which the leukocytes , erythrocytes, and platelets are suspended.
Term
Platelet
Definition
A clotting cell; a thrombocyte.
Term
Polycythemia Vera
Definition
Abnormal increase in the number of RBC'S granulocytes , and thrombocytes, leading to an increase in blood volume and viscosity (thickness).
Term
Prothrombin Times (PT)
Definition
a blood test used to evaluate the common pathway and extrinsic system of clot formation.
Term
Purpura
Definition
Collectio of blood beneath the skin in the form of pinpoint hemorrhages appearig as red -purple skin discoloration.
Term
Red Blood Cell Morpholoy
Definition
Examination of the RBCs on a stained blood smear that enables the examiner to identify the form and shape of the RBCs.
Term
Reticulocyte
Definition
Immature erythrocyte characterized by a meshlike pattern of threads and particles at the formaer site of the nucleus.
Term
Reticulocyte Count
Definition
A measurement of the numbers of cirulation reticulocytes , immarute erythrocytes in blood specimen.
Term
Rouleaux
Definition
An aggregation of RBCs viewed through the microscope that may be an artifact or may occur with persons with multiple myeloma as a result of abnormal protiens.
Term
Sacroidosis
Definition
A systemic inflammatory disease resulting in the formation of multiple small rounded lesions in the lungs , lymph nodes , eyes , liver , and other organs.
Term
Thrombosis
Definition
Abnormal condition in which a clot develops in a blood vessel.
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