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Chapter 8:
Muscular System
25
Medical
Not Applicable
12/02/2011

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Term
fascia
Definition
a sheet pf fibrous connective tissue that encloses a muscle
Term
aponeuroses
Definition
sheets of connective tissue that attach muscles
Term
myofibrils
Definition
contractile fibers in muscle cells
Term
myosin
Definition
a protein that, with actin, forms the filaments that contract muscle fibers
Term
actin
Definition
a protein that forms filaments that slide between filaments of the protein myosin, contracting muscle fibers
Term
sarcomeres
Definition
the structural and functional units of a myofibril
Term
sarcoplasmic reticulum
Definition
membranous network of channels and tubules of a muscle fiber, corresponding to the endoplasmic reticulum of other cells.
Term
transverse tubules (T-tubules)
Definition
membranous channels that extend inward from a muscle fiber membrane.
Term
motor neuron
Definition
a neuron that transmits impulses from the central nervous system to an effector
Term
neurotransmitters
Definition
chemicals that axons secrete on effectors (muscles or glands) or other neurons
Term
synapse
Definition
the functional connection between the axon of a neuron and the dendrite or cell body of another neuron or the membrane of another cell type.
Term
synaptic cleft
Definition
the space between two cells forming a synapse.
Term
neuromuscular junction (NMJ)
Definition
synapse between a motor neuron and a skeletal muscle fiber
Term
motor end plate
Definition
specialized part of a muscle fiber membrane at a neuromuscular junction
Term
motor unit
Definition
a motor neuron and its associated muscle fibers
Term
sliding filament model
Definition
thick and thin filaments do not change length. They slide past one another, with the thin filaments sliding toward the center of the sarcomere from both ends
Term
acetylcholine
Definition
a type of neurotransmitter, which is a biochemical secreted at axon ends as many neurons; transmits nerve messages across synapses
Term
acetylcholinesterase
Definition
an enzyme that catalyzes breakdown of acetylcholine
Term
muscle impulse
Definition
impulse that travels along the sarcolemma to the transverse tubules
Term
creatine phosphate
Definition
a biochemical that stores energy in muscle tissue
Term
oxygen debt
Definition
the amount of oxygen required after physical exercise to convert accumulated lactic acid to glucose
Term
hemaglobin
Definition
oxygen-carrying pigment in red blood cells
Term
myoglobin
Definition
a pigmented protein in muscle that carries oxygen
Term
Muscle Fiber Contraction
Definition
1. a nerve impulse travels down a motor neuron axon

2. the motor neuron terminal releases the neurotransmitter acetylcholine (ACh)

3. ACh binds to ACh receptors

4. the sarcolemma is stimulated, and a muscle impulse travels over the surface of the muscle fiber and deep into the fiber through the T-tubules

5. The muscle impulse reaches the sarcoplasmic reticulum and calcium channels open

6. Calcium ions diffuse from ghd sarcoplasmic reticulum ingo ghd sarcoplasm and bind to troponin molecules

7. tropomyosin molecules move and expose specific sites on actin

8. actin and myosin form linkages

9. thin (actin) filaments are pulled toward the center of the sarcomere by myosin cross-bridges

10. the muscle fiber shortens as a contraction occurs
Term
Muscle Fiber Relaxation
Definition
1. Acetylcholinesterase decomposes ACh and the muscle fiber membrane is no longer stimulated

2. calcium ions are actively transported into the sarcoplasmic reticulum
3. ATP breaks linkages between actin and myosin filaments without breakdown of the ATP itself.

4. breakdown of ATP cocks the cross-bridges

5. troponin and tropomyosin molecules inhibit the interaction between myosin and actin filaments

6. the muscle fiber remains relaxed, yet ready, until stimulated again
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