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chapter 6
metabolism, energy, and life
26
Biology
Not Applicable
05/04/2005

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Term
catabolic pathways
Definition
release of energy by breaking down complex molecules to simpler compounds.
Term
anabolic pathways
Definition
consume energy to build complicated molecules from simpler molecules.
Term
bioenergetics
Definition
study how organisms manage their resources.
Term
thermodynamics
Definition
study of energy transformations that occur in a collection of matter.
Term
first law of thermodynamics
Definition
The energy of the universe is constant. (energy can be transferred and transformed, but it can neither be created nor destroyed.)a.k.a. conservation of energy.
Term
second law of thermodynamics
Definition
every energy transfer or transformation makes the universe more disordered.
Term
entropy
Definition
measure of disorder
Term
free energy
Definition
energy available for work.
Term
exergonic raction
Definition
proceeds with a net release of free energy
(G is negative)

(delta G = delta H - T delta S)
Term
endergonic
Definition
absorbs free energy from its surroundings. (G is positive)

(delta G = delta H - T delta S)
Term
energy coupling
Definition
use of an exergonic process to drive an endergonic process.
Term
ATP (adenosine triphosphate)
Definition
immediate source of energy that powers cellular work.
Term
phosphorylated intermediate
Definition
receives a phosphate group and becomes more reactive (less stable) than the original molecule.
Term
catalyst
Definition
chemical agents that change the rate of a reaction without being consumed by the reaction.
Term
enzymes
Definition
catalytic proteins.
Term
free energy of activation/activation energy
Definition
initial investment of energy for starting reaction (energy required to break bonds in the reactant molecules) usually provided in the form of heat that the reactant molecules absorb form the surroundings.
Term
substrate
Definition
reactant an enzyme acts on.
Term
active site
Definition
restricted region of the enzyme molecule that actually binds to the substrate.
Term
induced fit
Definition
when the substrate binds with the enzyme. it induces the enzyme to change its shape slightly so that the active site fits even more snugly around the substrate.
Term
cofactors
Definition
nonprotein helpers that may be bound tightly to the active site as permanant residents or bind loosely and reversibly along with the substrate.
Term
coenzyme
Definition
name of the cofacter if it is an organic molecule.
Term
competitive inhibitors
Definition
mimics of substrate that reduce the productivity of enzymes by blocking the substrate from entering the active sites. (reversible by increasing concentration of substrate)
Term
noncompetitive inhibitors
Definition
binds to another part of the enzyme which causes the enzyme molecule to change its shape, making the enzyme unreceptive to substrate.
Term
allosteric site
Definition
specific receptor site on some part of the enzyme molecule remote from the active site.
Term
feedback inhibition
Definition
switching off of a metabolic pathway by its end-product (which acts as an inhibitor of an enzyme within the pathway)
Term
cooperativity
Definition
if one substrate binds to an enzyme molecule, then the whole enzyme is activated.
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