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Chapter 6
Thomas More College
56
Biology
Undergraduate 1
10/08/2012

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Term
What is thermodynamics?
Definition
it is the branch of chemistry concerned with energy changes
Term
define energy
Definition
the capacity to do work
Term
What is kinetic energy?
Definition
the energy of motion
Term
What is potiential energy?
Definition
stored energy 
Term
Name the forms of energy?
Definition
mechanical, heat, sound, electric, light, or radioactive
Term
what is a calorie?
Definition
it is the amount of heat energy required to raised one gram of water one degree celsius
Term
What is calorie labeled with a captail C?
Definition
a kilocalorie
Term
What is an oxidation-reduction reaction?
Definition
loss or gain of an electron in a reaction
Term
what is the first law of thermodynamics?
Definition
energy cannot be neither created nor destroyed
Term
What is the second law of thermodynamics?
Definition
entropy is constantly increasing in the universe
Term
What is entropy?
Definition
the disorder in the universe
Term
What is free energy?
Definition
the amount of energy avaliable to do work
Term
What is enthalpy?
Definition
the energy used to make and break bonds
Term
What is endergonic energy?
Definition
the inward energy, requires an input of energy
Term
What is exergonic energy?
Definition
outward energy, releases excess free energy
Term
What is the difference of equilibrum favoring of exergonic and endergonic reactions?
Definition
exergonic has an equilibrum favoring the products, and endergonic has an equilibrium favoring the reactants
Term
what is activation energy?
Definition
the extra energy needed to destabilize existing chemical bonds and intiate a chemical reaction
Term
As the activation energy lowers what happens to the reaction rate?
Definition
its goes faster
Term
What can lower the activation energy?
Definition
enzymes
Term
The rate of the reaction can be increased by what two things?
Definition
increasing the energy of reacting molecules and lowering the activation energy
Term
what is catalysis?
Definition
the process of influencing chemical bonds in a way that lowers the activation energy needed to initiate a reaction. 
Term
ATP is the building block for what?
Definition
RNA molecules
Term
What is ATP composed of?
Definition
a five carbon sugar (ribose), adenine, and a chain of 3 phosphates
Term
What is the key to understanding how ATP stores energy?
Definition
the triphosphate group
Term
Phosphate groups are what kind of charge?
Definition
highly negative
Term
What four things effect enzymes?
Definition
temperature, pH, inhibitors, and activators
Term
how is ADP made?
Definition
when ATPS outermost energy phosphate bond is hydroylzed, cleaving off the phosphate group on the end 
Term
Cells use ATP to drive what type of reaction?
Definition
endergonic
Term
Describe the cyclic fashion of ATP.
Definition
Cells use exergonic reactions to provide the energy needed to synthesize ATP from ADP +Pi. They then could use the hydrolysis of ATP to provide energy to drive the endergonic reactions needed. 
Term
How much ATP is generally stored?
Definition
a few second supply, but it constatantly making ADP
Term
Most enzymes are what?
Definition
Proteins
Term
What does the 3-D shape of an enzyme enable?
Definition
It stabalizes a temporary association between substrates
Term
What are substrates?
Definition
the molecules that will undergo the reaction
Term
What are active sites?
Definition
the pockets in globular proteins with clefts
Term
How does induced fit work?
Definition
it is the bondage between the substrate and the enzyme
Term
What is the multienzyme complex?
Definition
It is an assembly consisting of several enzymes catalyzing different steps in a sequence of reactions 
Term
what is intramolecular catalysis?
Definition
ribosomes that have folded structures and catalyze reactions on themselves
Term
what is intramolecular catalysis?
Definition
other ribozymes act on other molecules without being changed themselves
Term
what is the optimum temperature?
Definition
the highest temperature an enzyme-catalyzed reaction can reach
Term
What is the human enzyme optimum temperature?
Definition
35 to 40 degrees
Term
what is one way enzymes are held together?
Definition
between oppositely charged amino acids
Term
What does the optimum pH for enzymes usually range from?
Definition
6 to 8
Term
What is an inhibitor?
Definition
a substance that binds to an enzyme and decreases its activity 
Term
What is the feedback inhibition?
Definition
the end product is used as an inhibitor
Term
What is a competitive inhibitors?
Definition
they compete with the substrate for the same active site, occupying the active site and preventing substrates from binding
Term
What are noncompetitive inhibitors?
Definition
they bind to the enzyme in a location other than the active site
Term
What is allosteric enzymes?
Definition
enzymes that exist either as an active or inactive conformation
Term
Where does most noncompetitive inhibitors bind to?
Definition
an allosteric site
Term
What is an allosteric inhibitor?
Definition
a substance that binds to an allosteric site and reduces enzyme activity
Term
What are cofactors?
Definition
additional chemical componenets that help with enzyme function
Term
What is a coenzyme?
Definition
a cofactor that is a nonprotein organic molecule
Term
What is metabolism?
Definition
total of all chemical reactions carried out by an organism
Term
What is anabolism?
Definition
chemical reactions that expend energy to build up molecules
Term
What is a biological pathway and what is an example of it?
Definition
a sequence of chemical reactions in which the product of one reaction becomes the substrate of the next reaction , and the krebs cycle
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