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Chapter 5
Structure & Function of Macromolecules
25
Biology
Undergraduate 1
09/21/2008

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Term
List the four major classes of macromolecules.
Definition
Carbohydrates, Lipids, Protein and Nucleic acid.
Term
Distinguish between monomers and polymers.
Definition
Monomers are the building blockes of polymers. Polymers are long moleucles that consist of many similar or identical building blocks liked by covalent bonds. An example of a polymer is a carbohydrate, lipid, or protein.
Term
Draw diagrams to illurstrate condensation and hydrolysis reactions.
Definition
Term
Distinguish among monosaccharides, disaccharides, and polysaccharides.
Definition
Mono means single. Saccharide means sugar. Monosaccharides are single sugars/simple carbohydrates, or simple sugars such as glucose. Disaccharides are double sugars and consist of two monosaccharides. Polysaccharides are macromolecules; polymers with many monosaccharides joined by glycosidic linkages.
Term
Describe the formation of a glycosidic linkage.
Definition
A glycosidic linkage is a covalent bond formed betwen two monosaccharides by a dehydration reaction.
Term
Distinguish between the glycosidic linkages found in starch and cellulose. Explain why the difference is biologically important.
Definition
The glycosidic linkages in starch and cellulous are different due to their slightly different ring structures for glucose. In starch, the glucose monomers are arranged in an alpha configuration. In cellulose, the monomers are in a beta configuration. The structures are essentialy flip flopped from eathother.
Term
Distinguish between the glycosidic linkages found in starch and cellulose. Explain why the difference is biologically important.
Definition
The glycosidic linkages in starch and cellulous are different due to their slightly different ring structures for glucose. In starch, the glucose monomers are arranged in an alpha configuration. In cellulose, the monomers are in a beta configuration. The structures are essentialy flip flopped from eathother.
Term
Describe the role of symbiosis in cellulous digestion.
Definition
Enzymes are unable to digest the beta form of cellulose. In humans, the cellulose in our food poasses through the digestive tract and is eliminated with the feces. Although humans cannot digest cellulose, it helps line the inside of the tract to help food move through smoothly.
Term
Describe the building-block molecules, structure, and biological importance of fats, phospholipids, and steroids.
Definition
Fat or triacylglycerol: made from glycerol and 3 fatty acids. Structure is made through an ester linkage. The biological importance is that fat stores energy.
Phospholipids: Made of 2 fatty acids and glycerol. Their importance is that they are major cmponents of all cell membranes. They are linked to a pohsphate group.
Steroids: made of four fused rings. Their structure is a carbon skeleton. The importance is the managing of hormones.
Term
Identify an ester linkage and describe how it is formed.
Definition
An ester linkage is a bond between a hydroxyl group and a carboxyl group.
Term
Distinguish between saturated and unsaturated fats.
Definition
Saturated fats have zero double bonds between carbon atoms. Unsaturated fats have one or more double bonds. Unsaturated fats are easier for enzymes to break down than saturated fats are.
Term
Distinguish between saturated and unsaturated fats.
Definition
Saturated fats have zero double bonds between carbon atoms. Unsaturated fats have one or more double bonds. Unsaturated fats are easier for enzymes to break down than saturated fats are.
Term
Name the principal energy storage molecules of plants and animals.
Definition
The principal energy storage molecules of plants and animals is fat.
Term
Name the principal energy storage molecules of plants and animals.
Definition
The principal energy storage molecules of plants and animals is fat.
Term
Distinguish between a protein and a polypeptide.
Definition
Protein: consists of one or more polypeptides folded and coiled into specific conformations.
Polypeptides: polymers of amino acids.
Term
Explain how a peptide bond forms between two amino acids.
Definition
Peptide Bond: a covalent bond between two amino acid units, formed by a dehydration reaction.
Term
List and describe the four m ajor components of an amino acid. Explain how amino acids may be grouped according to the physical and chemical properties of the R group.
Definition
Amino group, carboxyl group, hydrogen atom, and variable group (represented with R). The r-group is a side chain and amino acids are grouped together by their side chains. The product of these groupings may be hydrophobic or hydrophilic.
Term
Explain what determines protein conformation and why it is important.
Definition
The amino acid sequence of a polypeptide determines the three-dimensional conformation or the protein. The conformation of a protein is important because it determins how it works.
Term
Explain how the primary strcture of a protein is determined.
Definition
The conformatino of a protein determines the structure of it.
Term
NAme two types of secondary protein sturcture. Explain the role of hydrogen bonds in maintaining secondary structure.
Definition
Examples: alpha helix and beta pleated sheet. The hydrogen bonds maintain this structure by repeating constituents of the polypeptide backbone.
Term
Explain how weak interactions and disulfide bridges contribute to tertiary protein structure.
Definition
The weak interactions between the side chains contribute to tertiary protein structure. The hydrophobid interaction also contributes to the tertiary structure.
Term
LIst four conditions under which proteins may be denatured.
Definition
pH, salt concentration, temperature, or alteration of other aspects of the environment.
Term
List the major components of a nucleotide and describe how these monomers are linked to forma nucleic acid.
Definition
a nitrogenous base, a pentose (five-carbon sugar), and a phosphate group.
Term
Distinguish between:
a. pyrimidine and purine
b. nucleotide and nucleoside
c. ribose and deoxyribose
d. 5' end and 3' end of a nucleotide
Definition
a. pyrimidine: a six-membered ring of carbon and nitrogen atoms.
Purine: larger with six-membered ring fused to a five-member ring.
b. nucleotide: composed of three parts, a nitrogenous base, a pentose, and a phosphate group.
Nucleoside: the part of the nucleotide iwthout a phosphate group.
Term
Briefly describe the three-dimentional structure of DNA.
Definition
DNA molecules have two polynucleotides that spiral around an imaginary axis. It forms a double helix.
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