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Chapter 46 Pharm
Peptic Ulcer Disease
16
Pharmacology
Graduate
09/02/2012

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Cards

Term
Cimetidine MOA
Definition
H2 receptor blockage
Term
Cimetidine AE
Definition
gynecomastia, galactorrhea, Enterocolitis in fetus, agranulocytosis, DO NOT USE IN PREGNANCY
Term
Ranitidine, Gamotidine, and Nizatidine MOA
Definition
blocks H2 receptor
Term
Nizatidine special?
Definition
Only excreted thru kidneys, all rest H2 both renal and live
Term
Omeprazole, Esomeprazole, Lansoprazole MOA
Definition
irreversibly inhibit H/K ATPase on parietal cells
Term
PPI's special
Definition
Can be used with NSAID but are expensive
Term
Aluminum hydroxide AE
Definition
phosphate depletion (weakness, malaise, anorexia) CONSTIPATION, osteomalacia
Term
Aluminum hydroxide AE
Definition
phosphate depletion (weakness, malaise, anorexia) CONSTIPATION, osteomalacia
Term
Manesium hydroxide AE
Definition
Diarrhea, hypermagnesemia
Term
Sodium bicarbonate TX
Definition
dyspepsia, metabolic acidosis, urinary alkalinization, uric acid renal stones
Term
Calcium carbonate TX
Definition
dyspepsia and osteoporosis
Term
Sucralfate
Definition
coats mucosa with protective layer, can accumulate AL and constipation
Term
Colloid bismuth AE
Definition
darken stools tonge and nausea vomiting
Term
Dicyclomine
Definition
inhibits ACH binding to ACH receptors
Term
Dicyclomine AE
Definition
Dry mouth , blurred vision, tachycardia, urinary retention, constipation
Term
Misoprostol
Definition
PGE1 analogue, can also be used for abortions
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