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Chapter 43
Animal Development
90
Biology
Undergraduate 2
03/13/2006

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Term
Sexual Reproduction
Definition
The process where two cells (gametes) fuse to form one fertilized cell or zygote.
Term
Cost of Sexual Reproduction
Definition
1. gamete timing
2. selecting a male/female (sexual selection)
3. seperate sexes
4. nourishment and care of young.
Term
Gamete Timing
Definition
built-in controls that synchronize the timing of gamete formation and sexual readiness in two individuals.
Term
Reproductive timing depends on...
Definition
enery outlays for constructing, maintaining, and operating neutral as well as hormonal control mechanisms in each parent.
Term
What must line up between the two parents?
Definition
Parents must produce mature gametes in reponse to the same cues, such as seasonal change in daylight, that mark the onset of appropriate time of reproduction for their species.
Term
Whats involved in locating and recognizing a likely mate?
Definition
Production of pheromones, visual signals, courtship and keeping mates.
Term
Costs of internal fertilization:
Definition
They invest metabolic ebergy to construct elaborate reproductive organs.
Term
Cost of external fertilization:
Definition
invest energy into making numerous (often thousands) of gametes.
Term
Nearly all animal eggs contain..
Definition
yolk.
Term
Yolk
Definition
Rich in proteins and lipids, it nourishes embryotic stages.
Term
Do human eggs contain yolk?
Definition
Yes, but very little. Fetus is sustained through pregnancy by physical exchanges with the mothers tissue.
Term
Embryos
Definition
a class of transitional forms between the fertilized egg and the adult.
Term
Stages of animal development:
Definition
gamete formation
fertilization
cleavage
Term
Gamete formation
Definition
first stage
eggs or sperm develop inside the reproductive organs of the parent body.
Term
Fertilization
Definition
second stage
starts when a sperms plasma membrane fuses with the eggs plasma membrane.
Term
When does fertilization end?
Definition
when the sperm nucleus and egg nucleus fuse and form a zygote.
Term
cleavage
Definition
third stage
a program of mitotic cell divisions that divide the volume of egg cytoplasm into a number of blastomeres.
Term
Blastomeres
Definition
smaller cells, each with its own nucleus.
Term
During cleavage, what increases and what stays the same?
Definition
The number of cells increase, but there is no overall growth.
Term
Gastrulation
Definition
Pace of mitotic division slackens.
A time of cellular reorganization.
Germ layers develop.
Term
Germ layer
Definition
The new cells become arranged into a gastrula with 2 or 3 primary tissues, called germ layers.
Term
Why is the germ layer important?
Definition
The cells that make up the germ layer give rise to all tissue and organs in the adult.
Term
The three types of tissue:
Definition
Ectoderm
Endoderm
mesoderm
Term
What type of tissue forms first?
Definition
Ectoderm
Term
What does the ectoderm give rise to?
Definition
nervous system
integumentary system
Term
Where is the endoderm located?
Definition
It is the inner most layer.
Term
What does endoderm give rise to?
Definition
guts inner lining and organs derived from the gut.
Term
What does the mesoderm give rise to?
Definition
muscle
skeletal
circulatory
reproductive
excretory
connective tissue
Term
Which layer evolved hundreds of millions of years ago and was a pivotal step in the evolution of nearly all large, complex animals?
Definition
mesoderm
Term
What happens after the primary tissue layers form?
Definition
they give rise to subpopulations of cells. Diverse tissues and organs start to form from their cellular descendants.
Term
Last stage of animal development?
Definition
growth and tissue specialization
Term
What happens during growth and tissue specialization?
Definition
tissues and organs gradually assume their final shape, size, proportions, and functions.
This stage goes on into adulthood.
Term
Gray Cresent
Definition
Appears on the surface of the embryo and establishes the bodies anterior, posterior axis.
Term
Blastula
Definition
A ball of cells with fluid-filled cavity called a blastocoel.
Term
Frog Egg
Stages of animal formation
Definition
1. a jelly-like layer that surrounds the frog egg has been removed.
2. about an hour after fertilization, the gray cresent forms. Gastrulation starts here.
3. Cleavage produces a blastula.
4. cells actively migrate to new locations and are rearranged during gastrulation.
5. primary tissue layers form, then a primitive gut cavity i which internal organs will become suspended.
Cell differentiation proceeds, moving the embryo on its way to becoming a tadpole.
Term
What happens to an oocyte when it is maturing?
Definition
Its volume increases, enzymes, RNA transcripts and other factors become stockpiled in different parts of the cytoplasm.
Term
What is the function of tubulin molecules in the oocyte?
Definition
Will help control the angle and timing of tubulin assembly into microtubules for mitotic spindles.
Term
What influences how large the blastomeres are?
Definition
The amount of yolk.
Term
What action in the frogs egg proves the effect of "maternal messages?"
Definition
At fertilization, part of the granule-containing cortex shifts toward the point of sperm entry. This exposes lighter-colored, yolky cytoplasm in a crescent shaped gray area. The first cleavage normally puts part of the gray cresent in both of the resulting blastomeres.
Term
Describe the experiment that proved the importance of the gray cresent (and therefore, maternal messages):
Definition
In one experiment, the blastomeres that formed were physically seperated from each other. Each still gave rise to a tadpole. In the next experiment, a fertilized egg was manipulated so the cut through the first cleavage plane missed the gray cresent. The blastomere with the gray cresent developed into a tadpole, and the one without turned into a ball of undifferenciated cell forms.
Term
How are the blastomere seperated?
Definition
Cleavage Furrow- Underneath the plasma membrane, its midsection has a ring of microfilaments made of the contractile protein actin.
Term
Cytoplasmic localization
Definition
Simply by virtue of where they form, blastomeres end up with different maternal messages.
Term
What is the point of cytoplasmic localization?
Definition
It helps seal the developmental fate of each cells descendants.
Term
What controls how fast the cuts proceed and what arrangement the blastomeres will be in in most animals?
Definition
Proteins and mRNA's stockpiled in the cytoplasm.
Term
What controls cleavage patterns in mammals?
Definition
Certain genes must be activated first. Cleavage cannot be completed without the protein products of those genes.
Term
What effect does the amount of yolk have on the cleavage pattern?
Definition
Cuts can go right through a nearly yolkless egg. Early cuts only go through partially in an egg stockpiled with yolk. The egg therefore has polarity.
Term
vegetal pole
Definition
yolk-rich end
Term
animal pole
Definition
closer to the nucleus
Term
Radial Cleavage
Definition
cleavage furrows run horizontal and vertical to animal-vegetal axis.
Term
What do cuts in the oocyte produce?
Definition
blastula
Term
blastula
Definition
an embryonic stage in which the blastomeres surround a fluid filled cavity (a blastocoel)
Term
Why is a frog egg shaped like a mulberry?
Definition
Because of the yolk, more, smaller blastomeres form near its animal pole, and the blastoceol is offset.
Term
What is another name for an amphibian blastula?
Definition
morula
Term
What kind of cleavage do eggs of reptile, birds and most fishes undergo?
Definition
incomplete cleavage
Term
Incomplete Cleavage
Definition
The large volume of yolk restricts the early cuts to a small, caplike region near the animal pole.
Term
What is the shape of the oocyte after incomplete cleavage?
Definition
Two flattened layers of cells with a narrow cavity inbetween.
Term
what type of cleavage do mammalian eggs undergo?
Definition
rotational cleavage
Term
rotational cleavage
Definition
blasomeres divide slowly at different times
Term
Explain what types of cuts are made and when during rotational cleavage:
Definition
1-vertical through both poles. 2- one blastomere is cut horizontally, the other vertically. 3-yields a loose arrangement with space between eight cells. Cells undergo compaction.
Term
How to tight and gap juctions come into play when talking about rotational cleavage?
Definition
Tight juctions stabilize the blastomeres outside and seal off the ones inside. Gap Junctions form between the inner cells and facilitate chemical communication among them.
Term
What is the purpose of the descendents of the cells on the outer layer during rotational cleavage?
Definition
They Form a thin surface layer.
Term
Blastocyst
Definition
A type of blastula. Secretions from the cell descendence of the outer layer form a fluid filled cavity in the ball,and the inner cells mass together against one side of it.
Term
How are identical twins formed?
Definition
When the first two blastomeres, the inner cell mass, and even a later stage splits.
Term
How are fraternal twins formed?
Definition
Arise from two oocytes that matured and then became fertilized during the same menstral cycle.
Term
How are identical twins different than fraternal twins?
Definition
Identical twins have identical genetic makeups, and share a placenta. Fraternal twins have unique DNA and are serviced by different plancentas.
Term
The three layer body plan shared by nearly all animals:
Definition
gut, surface parts, organs.
Term
When does the three part body plan emerge?
Definition
as cleavage ends and gastrulation begins.
Term
What determines where the neural tube will form?
Definition
The anterior-posterior axis
Term
Neural Tube
Definition
The forerunner of a brain and spinal cord.
Term
All cells of an embryo have the same...
Definition
number and kinds of genes.
Term
What happens to the genes in the cells from gastrulation onwards?
Definition
Certain groups of genes are used in some cell but not in others.
Term
Cell differentiation
Definition
When a cell selectively activates genes and synthesizes proteins not found in other cells types.
Term
crystallins
Definition
a family of proteins that are assembled into transparent fibers for each lens.
Term
Who did the experiment that proved that nearly all cells differentiate without losing any genetic information?
Definition
John Gurdon
Term
Describe the experiment done by John Gurdon:
Definition
Gurdon stripped unfertilized eggs of an African Clawed frog of their nucleus. He then inserted full differentiated intestinal cells from a tadpole of the same species.
Term
What was the outcome of Gurdons experiment?
Definition
Some of the eggs still gave rise to a complete frog.
Term
Why did Gurdons experiment turn out the way it did?
Definition
The intestinal cells still had the same number and kinds of genes as a zygote, its nucleus still had all the genes required to make all cell types that made up the frog.
Term
Morphogenesis
Definition
refers to the program of orderly changes in an embryo's size, shape, and proportions.
Term
What is the result of morphogenesis?
Definition
specialized tissues and early organs
Term
How do cells move around?
Definition
They use pseudopods that move them along prescribed routes.
Term
What do cells do when they reach their prescribed location?
Definition
they establish contact with the cells already there.
Term
How do cells know where to go?
Definition
They respond to chemical gradients and adhesive cues.
Term
example of adhesive cues
Definition
When migrating nerve cells stick to adhesion proteins on glial cells but not blood vessels.
Term
Chemical gradients
Definition
Coordinated by the synthesis, release, deposition, and removal of specific chemicals in the extracellular matrix.
Term
How do adhesive cues tell the cell when to stop?
Definition
Cells will migrate to regions of strongest adhesion, but once there, further migration is impeded.
Term
what happens after the three primary tissues form in embryos?
Definition
the neural tube forms
Term
How does the neural tube form?
Definition
At the embryo midline, ectodermal cells elongate and form a neural plate. Specific cells lengthen, or some become wedge shaped. The changes in shape cause tissue flaps to fold over and meet at the midline, thus forming the neural tube.
Term
Apotosis
Definition
Programmed cell death
Term
How does apotosis help form the fetus's hand?
Definition
Cartilage models of finger form inside the "paddle." Cells in thin tissue zones between the digits have receptors for proteins (a product of selective gene expression). When proteins bind to those receptors, the cells die and the fingers seperate.
Term
What causes changes in cell shape?
Definition
Microtubules lengthen and microfilament rings constrict inside cells.
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