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Chapter 3 - Bio 111
Test 1
111
Biology
Undergraduate 3
09/23/2013

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Term
What do biological molecules mainly consist of?
Definition
1.) Carbon bonded to carbon
2.) Carbon bonded to other elements (O,N,S,P, or H)
Term
How many covalent bonds does carbon usually form?
Definition
4
Term
What are the groups that carbon bond to called?
Definition
Functional groups
Term
What is the structural formula for a hydroxyl group? What is it found in?
Definition
-OH. Carbohydrates, proteins, nucleic acids, lipids
Term
What is the structural formula for a carbonyl group? What is it found in?
Definition
O
II
-C -

Carbohydrates, nucleic acids
Term
What is the structural formula for a carboxyl group? What is it found in?
Definition
O
II
-C-OH

Proteins, lipids.
Term
What is the structural formula for an amino group? What is it found in?
Definition
-N-H
I
H

Proteins, nucleic acids
Term
What is the structural formula for a Sulfhydryl group? What is it found in?
Definition
-S-H

Proteins
Term
What is the structural formula for a phosphate group? What is it found in?
Definition
O-
I
-O-P-O
II
O

Nucleic acid
Term
What is the structural formula for a methyl group? What is it found in?
Definition
H
I
-C-H
I
H

Proteins
Term
What is an isomer?
Definition
Molecules with the same molecular formula or empirical formula.
Term
What is a structural isomer?
Definition
a form of isomerism in which molecules with the same molecular formula have bonded together in different orders

Functional group is in a different location.

DIFFERENT FXN EVEN THOUGH THEY HAVE SAME FORUMLA
Term
What is a stereoisomer?
Definition
they are made of the same atoms, connected in the same sequence, but the atoms are positioned differently in space. The difference between two stereoisomers can only be seen when the three dimensional arrangement of the molecules is considered.

MIRROR IMAGE OF ANOTHER MOLECULE.
Term
What is an enantiomer?
Definition
Molecules that are mirror images of each other.
Term
What is a chiral center?
Definition
A carbon that has 4 different things attached to it
Term
What is a biological molecule?
Definition
Typically large molecules constructed from smaller subunits.
Term
What is a monomer?
Definition
A single subunit
Term
What is a polymer?
Definition
Many units. Built by linking monomers.
Term
What is dehydration synthesis?
Definition
Formation of large molecules by the removal of water. Monomers are joined to form polymers.
Term
What is hydrolysis?
Definition
Breakdown of large molecules by the addition of water. Polymers are broken down into monomers.
Term
What is a the ratio of carbon, hydrogen, and oxygen in a carbohydrate?
Definition
1 Carbon, 2 Hydrogen, 1 Oxygen.

1:2:1
Term
What is the empirical formula for carbohydrates?
Definition
(CH2O)2
Term
What bond in a carbohydrate holds the most energy?
Definition
C-H
Term
What are carbohydrates function?
Definition
Good energy storage for molecules. EX: Sugars, starch, and glucose.
Term
What is glucose?
Definition
A MONOsaccharide.
Term
How many carbons does a glucose contain?
Definition
6.
Term
Can glucose form ring structures?
Definition
Yes
Term
What is an alpha connection?
Definition
Faces UPWARDS
Term
What is a beta connection?
Definition
Faces DOWNWARDS
Term
Fructose is a __________ isomer of glucose.
Definition
structural. The double bonded oxygen is bonded at a different at a location.
Term
Galactose is a __________ isomer of glucose.
Definition
Stereo. The H-C-OH in glucose is an OH-C-H in galactose.
Term
How can enzymes distinguish the difference between structural and stereoisomers?
Definition
They act different depending on the structure of a 6-carbon sugar.
Term
What is a disaccharide?
Definition
2 monosaccarides linked together
Term
How are disaccharides formed?
Definition
Dehydration synthesis.
Term
What are disaccharides used for?
Definition
Transport or energy storage.
Term
What is an example of a disaccharide?
Definition
Sucrose, lactose, maltose
Term
What is a polysaccharide?
Definition
Long chains of monosaccharides linked together by dehydration synthesis.
Term
What are the functions of a polysaccharide?
Definition
1.) Energy Storage
2.) Structural Support
Term
What do plants use for energy?
Definition
Starch/Amylose
Term
What do animals use for energy?
Definition
Glycogen.
Term
What do plants use as support?
Definition
Cellulose - a structural carbohydrate/polymer
Term
What do arthopods and fungi use for support?
Definition
Chitin
Term
What is a polymer nucleic acid called?
Definition
Nucleic acids
Term
What is a monomer of a nucleic acid?
Definition
Nucleotides
Term
What is the basic structure of a nucleic acid?
Definition
Sugar + Phosphate + Nitrogenous Base
Term
What are the 2 types of nitrogenous bases?
Definition
1.) Purines
2.) Pyrimidines
Term
What are the 2 purines?
Definition
Adenine and Guanine
Term
What are the pyrimidines?
Definition
Thymine, cytosine, uracil.
Term
What are the bases found in DNA?
Definition
Adenine, Guanine, Thymine, and Cytosine.
Term
What are the bases found in RNA?
Definition
Adenine, Guanine, Uracil, Cytosine
Term
How are nucleotides connected?
Definition
By phosphodiester bonds.
Term
What is the function of Nucleic Acids?
Definition
Information storage and use.
Term
Is a hydroxyl group attached to a sugar in a Nucleotide structure indicative RNA or DNA?
Definition
RNA
Term
Is a hydrogen attached to a sugar in a Nucleotide structure indicative of RNA or DNA?
Definition
DNA
Term
Where are primes in RNA and DNA?
Definition
Sugar, not in the the base.
Term
What is the main difference between purines and pyrimidines?
Definition
The purines have a nitrogen pentagon situation attached where pydimidines are just a hexagon.
Term
How do DNA bases bond?
Definition
A with T, C with G
Term
How do RNA bases bond?
Definition
A with U, C with G
Term
What does DNA do?
Definition
encodes information for amino acid sequence of proteins based on the sequence of bases.
Term
What is the structure of DNA?
Definition
2 different polynucleotide strands connected by hydrogen bonds. A double helix
Term
What holds together DNA?
Definition
A bunch of hydrogen bonds.
Term
What is the major difference in RNA and DNA?
Definition
RNA's sugar is ribose instead of DNA's deoxyribose.
Term
How do the base pairs in RNA and DNA differ?
Definition
RNA has uracil instead of thymine.
Term
How does the structure of RNA different than in DNA?
Definition
RNA is a single stranded polynucleotide.
Term
What is DNA used for?
Definition
It acts as a template for the creation of RNA
Term
What is RNA used for?
Definition
It creates proteins.
Term
What does ATP stand for?
Definition
Adenosine triphosphate
Term
What is ATP used for?
Definition
Primary energy currency of a cell
Term
What are NAD and FAD?
Definition
Electron carriers that are important in many cellular reactions
Term
What are the 7 fxns of proteins?
Definition
1.) Enzyme catalysts
2.) Defense
3.) Transport
4.) Support
5.) Motion
6.) Regulation
7.) Storage
Term
Proteins are _____mers.
Definition
Polymers
Term
What is each chain of protein?
Definition
A polypeptide
Term
What are the monomer subunits of a protein?
Definition
Monomer subunits.
Term
What is the structure of an amino acid?
Definition
R
I
H2N-C-COOH
I
H
Term
What is COOH is an amino acid?
Definition
Carboxyl group
Term
What is the R of an amino acid?
Definition
The variable group. Could be anything.
Term
How are amino acids joined?
Definition
Through dehydration synthesis
Term
What are the bonds between amino acids?
Definition
Peptide bonds
Term
Where are the peptide bonds in amino acids?
Definition
Formed between the amine group and carboxyl group of 2 monomers.
Term
What is a dipeptide?
Definition
2 amino acids joined by 1 peptide bond
Term
What is a tripeptide?
Definition
3 amino acids joined by 2 peptide bonds.
Term
What does the R group in an amino acid dictate?
Definition
The chemical properties of the amino acid
Term
What are the 5 ways amino acids can be classfiied?
Definition
1.)Nonpolar
2.)Polar
3.)Charged
4.)Aromatic
5.)Special Fxn
Term
Look at table in chapter 3 slide for examples of amino acids
Definition
Term
What is the primary structure of a protein?
Definition
The sequence of amino acids
Term
What is the secondary structure of a protein?
Definition
Interraction of groups in the peptide back bone. Can form an alpha helix or a beta sheet.
Term
What is the tertiary structure of a protein?
Definition
The final folded shape of a globular protein. The overall 3D structure which is the key to how it interacts. Consists of a single polypeptide chain
Term
What is the quaternary structure of a protein?
Definition
Arangement of the individual polypeptide chains in a protein.
Term
What are the types of bonds that hold proteins together?
Definition
1.) Hydrogen bonds
2.) Disulfide bridges
3.) Ionic bonds
4.) Van Der Waals Attractions
5.) Hydrophobic exclusions
Term
What are Van Der Waals attractions?
Definition
Attraction due to polarized electron clouds.
Term
What are the hydrophobic exclusions?
Definition
Aggregate together, away from H20.
Term
What are motifs?
Definition
Common units of secondary structure seen in many polypeptides. Useful in determining function of unknown protein.
Term
What are domains?
Definition
Function regions of a polypeptide, most have multiple functional domains.
Term
What do chaperone proteins do?
Definition
Help to ensure that proteins fold correctly.
Term
When is a time that chaperon proteins are produced?
Definition
Under heat stress
Term
What is a disease that has a deficiency in chaperon proteins?
Definition
Cystic fibrosis.
Term
What is denaturation?
Definition
Protein loses structure and therefor function. Influenced by environmental conditions.
Term
What influences denaturation?
Definition
1.)pH
2.)temp
3.)ionic concentration of solution
Term
What is a lipid?
Definition
A group of molecules that are insoluble in water.
Term
What causes a lipid to be hydrophobic?
Definition
The high proportion of nonpolar C-H bonds
Term
What is a lipid's fxn?
Definition
Storage of large amounts of energy
Term
What are some examples of lipids?
Definition
Oils, fats, waxes, vitamins.
Term
What is a triglyceride composed of?
Definition
1 glycerol and 3 fatty acid chains.
Term
What does a saturated fatty acid mean?
Definition
NO DOUBLE BONDS
Term
What does an unsaturated fatty acid mean?
Definition
1 OR MORE DOUBLE BONDS
Term
Which type of triglyceride has a higher melting point (un or saturated)?
Definition
Saturated. Animal origin. Lard
Term
Which type of triglyceride has a lower melting point?
Definition
Unsaturated. Plant based. Olive oil.
Term
How are trans fats created?
Definition
Industrially.
Term
What are phospholipids composed of? What do they form?
Definition
A glycerol, 2 nonpolar fatty acid tails, and a polar phosphate head. All biological membranes.
Term
How is a biological membrane/ lipid bilayer created?
Definition
Cluster hydrophobic regions of phospholipids together and leave the hydrophilic region exposed to the water envirnment.
Term
What are micelles?
Definition
Lipid molecules that orient with polar head towards water and nonpolar tails away from water.
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