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Chapter 3
Integumentary System
94
Medical
Not Applicable
06/21/2005

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Term
epidermis
Definition
layer of the skin that consists of several layers of stratified squamous (scalelike) epithelium.

1. Cells are produced in the innermost (basal) layer moving the older cells up toward the surface.

2. Cells that are pushed up flatten, fill with a hard protein called keratin and die

3. Layers of packed dead cells accumlate in the outermost (squamous) layer where they are sloughed off.
Term
dermis
Definition
Layer of the skin known as the connective tissue layer, contains blood vessels, nerves, and other structures. Collagen fibers make the skin tough and elastic.
Term
subcutaneous layer
Definition
below the dermis composed of loose connective tissue and adipose (fatty) tissue.
Term
adip/o
lip/o
steat/o
Definition
fat
Term
derm/o
dermat/o
cutane/o
Definition
skin
Term
erythr/o
Definition
red
Term
hidr/o
Definition
sweat
Term
hist/o
histi/o
Definition
tissue
Term
kerat/o
Definition
hard
Term
leuk/o
Definition
white
Term
melan/o
Definition
black
Term
myc/o
Definition
fungus
Term
onych/o
Definition
nail
Term
plas/o
Definition
formation
Term
purpur/o
Definition
purple
Term
seb/o
Definition
sebum (oil)
Term
squam/o
Definition
scale
Term
trich/o
Definition
hair
Term
xer/o
Definition
dry
Term
xanth/o
Definition
yellow
Term
primary lesion
Definition
lesions arising from previously normal skin
Term
secondary lesion
Definition
lesions that result in changes in primary lesions
Term
macule
Definition
flat discolored spot on the skin up to 1 cm across (e.g. freckle)
Term
patch
Definition
flat, discolored areas on skin >1 cm across (e.g. vitiligo)
Term
papule
Definition
solid mass on the skin up to .5 cm in diameter (e.g. nevus or mole)
Term
plaque
Definition
a solid mass greater than 1 cm in diameter limited to the surface of the skin
Term
nodule
Definition
solid mass greater than 1 cm extending deeper into the epidermis
Term
tumor
Definition
solid mass larger than 1-2 cm
Term
wheal
Definition
area of localized skin edema (e.g. a hive)
Term
pustule
Definition
pus filled sac, e.g. a boil
Term
vesicle
Definition
little bladder, elevated fluid filled sac (blister) within or under the epidermis up to 5 cm
Term
bulla
Definition
a blister larger than 5 cm e.g. a second degree burn
Term
erosion
Definition
gnawed away; loss of superficial epidermis leaving an area of moisture but no bleeding
Term
ulcer
Definition
open sore on the skin or membranes that can bleed and scar. Sometimes accompanied by infection
Term
fissure
Definition
linear crack in the skin
Term
excoriation
Definition
a scratch mark
Term
crust
Definition
dried residue of serum, pus, or blood on the skin (e.g. impetigo)
Term
scale
Definition
a thin flake of exfoliated epidermis (e.g. dandruff)
Term
cherry angioma
Definition
small round bright red blood vessel tumor on the skin often on trunk of elderly
Term
spider angioma
Definition
tiny red blood vessel lesions formed by the dialation of a group of blood vessels radiation from a central arteriole, most commonly face neck or chest
Term
purpuric lesions
Definition
lesions resulting from hemmorages in the skin
Term
ecchymosis
Definition
a bruise, black and blue mark, large purpura
Term
petechia
Definition
spot, reddish brown minute hemorrhagic spots on the skin that indicate a bleeding tendency
Term
epidermal tumor
Definition
tumors arising from the epidermis
Term
nevus
Definition
birthmark, congential malformation can be epidermal or vascular - e.g. mole
Term
verucca
Definition
a wart; epidermal tumor caused by the papilloma virus.
Term
alopecia
Definition
fox mange, baldness natural or unnatural deficiency of hair
Term
comedo
Definition
a blackhead caused by a plug of sebum within the opening of a hair folicle.
Term
eruption
Definition
appearance of a skin lesion
Term
erythema
Definition
redness of the skin
Term
pruritus
Definition
severe itching
Term
rash
Definition
general term used for skin eruption, most often associated with a communicable disease.
Term
suppuration
Definition
production of purulent matter (pus)
Term
urticaria
Definition
hives, an eruption of wheals on the skin accelerated by an itch
Term
xeroderma
Definition
dry skin
Term
skin pigmentation
Definition
skin color due to presence of melanin

- depigmentation
- hyperpigmentation
- hypopigmentation
Term
acne
Definition
inflammation of the sebaceous glands and hair folicles evidenced by comedones (blackheads), pustules, or nodules on the skin
Term
albinism
Definition
hereditary condition characterized by a partial or total lack of melanin pigment (particularly hair, eyes, and skin)
Term
esanthematous viral disease
Definition
eruption of the skin caused by a viral disease

1. rubella - reddish german measles
2. rubcola - reddish, 14 day measles
3. varicella - a tiny spot, chicken pox
Term
furuncle
Definition
boil, a painful nodule formed in the skin by an inflammation originating in a hair folicle. Caused by staph.
Term
carbuncle
Definition
skin infection consisting of clusters of furuncles
Term
abscess
Definition
localized collection of pus in a cavity formed by the inflammation of surrounting tissues
Term
gangrene
Definition
an eating sore, death of tissue associated with a loss of blood supply to the area
Term
HSV-1
Definition
herpes simplex virus type 1. transmitted virally vesicles that infect the facial area, especially the mouth and nose
Term
HSV-2
Definition
herpes simplex virus 2 - sexually transmitted viral vesicles
Term
herpes zoster
Definition
virual disease affecting the peripheral nerves
Term
impetigo
Definition
highly contagious, bacterial skin inflammation marked by pustules that rupture and become crusted around mouth and nostrils
Term
actinic keratosis
Definition
localized thickening of the skin caused by excessive exposure to sunlight
Term
seborrheic keratosis
Definition
benign wart-like tumors (on elderly)
Term
squamous cell carcinoma
Definition
malignant tumor of squamous epithelium
Term
basal cell carcinoma
Definition
malignant tumor of the basal layer of the epidermis - most common type of skin cancer
Term
malignant melanoma
Definition
malignant tumor composed of melanocytes
Term
kaposis sarcoma
Definition
malignant skin cancer tumor of the walls of blood vessels appearing as painless dark blue spots
Term
scabies
Definition
contagious disease caused by a parasite (mite) that invades the skin causing an intense itch - typically on fingers, toes, and elbows
Term
pediculosis
Definition
infestation of lice that causes itching and dermatitis
Term
psoriasis
Definition
itching, chronic recurrent skin disease marked by silver gray scales covering red patching on the skin
Term
seborrhea
Definition
skin condition marked by the hypersecretion of sebum from the sebacious glands
Term
tinea
Definition
group of fungual skin diseases identified by the body part affected

- tinea corpus (called ringworm)
- tinea pedis (called athlete's foot)
Term
vitiligo
Definition
condition caused by the destruction of melanin that results in the appearance of white patches on the skin
Term
biopsy (Bx)
Definition
removal of a small piece of tissue for microscopic pathologic examination

1. excisional
2. incisional
3. shave
Term
culture and sensitivity (C&S)
Definition
technique of isolating and growing colonies of microorganisims to identify a pathogen to determine which drugs might be effective for a cure
Term
cryosurgery
Definition
destruction of tissue by freezing with an application of an extremely cold chemical (e.g. liquid nitrogen)
Term
debridement
Definition
removal of dead tissue from a wound or burn site to promote healing and prevent infection
Term
curettage
Definition
cleaning, scraping a wound using a spoonlike instrument called a curette - used for debridement
Term
incision and drainage (I&D)
Definition
incision and drainage of an infected skin lesion
Term
laser surgery
Definition
surgery using a laser in various dermatological procedures to remove lesions
Term
electrocautery
Definition
instrument heated by electric current (cautery), used to coagulate bleeding areas
Term
anesthetic
Definition
a drug that temporarily blocks transmission of nerve conduction to produce a loss of sensations
Term
antifungual
Definition
kills or prevent the growth of fungi
Term
antibiotic
Definition
kills or inhibits the growth of microorganisms
Term
antihistamine
Definition
blocks the affects of histamine in the body
Term
anti-inflammatory
Definition
reduces inflammation
Term
antipruritic
Definition
relieves itching
Term
antiseptic
Definition
inhibits the growth of microorganisms
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