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Chapter 3
Cells: The Living Units
35
Anatomy
Undergraduate 2
09/15/2010

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Term
Cell Theory (4parts)
Definition
1. Cell is the basic structural and functional unit of living organisms
2. An organism depends on both individual and collective properties of cells
3. 'Principle of complementarity of structure and function': biochemical activities cells dictated by specific subcellular structure.
4. Continuity of life generation to generation has cellular basis
Term
Cells that connect body parts, form linings, or transport gasses (3)
Definition
Fibroblasts, Erythocytes, Epithelial cells
Term
Cells that move organs and body parts (2)
Definition
Skeletal Muscle cell, Smooth muscle cells
Term
Cells that store nutrients
Definition
Fat Cells
Term
Cell that fights disease
Definition
Macrophage
Term
Cell that gathers information and control body functions
Definition
Nerve cell
Term
Cell of reproduction
Definition
Sperm
Term
Integral proteins of membrane and 5 types
Definition
Integral proteins are firmly inserted into lipid bilayer
1. Transport
2. Receptors
3. Structural
4. Enzymes
5. Cell: cell recognition (glycocalyx)
Term
Transport protein (what type of membrane protein and function)
Definition
Integral protein
-Carriers and pores
-Move stuff through bilayer
Term
Receptor proteins (what type of membrane protein and function)
Definition
Integral Protein
-External, signal transduction
-Chemical messenger attaches to receptor and causes a change in shape which initiates a chemical reaction in cell.
Term
Structural (what type of membrane protein and function)
Definition
Integral protein
-cell movement, bind cells together, keep shape
Term
Enzymatic proteins (what type of membrane protein and function)
Definition
Integral Protein
-enzyme built into membrane
-catalyzes metabolic pathway
Term
Cell-cell recognition proteins (what type of membrane protein and function)
Definition
Integral protein
-recognize other cells
-(glycoproteins)have idetification tags recognized by other cells
Term
Peripheral Proteins and function
Definition
on membrane of cell attached loosely to integral proteins
-easily removed
-Enzymes, motor proteins (cell shape), cell to cell lings, provide support on intracellular surface
Term
3 factors that act to bind cells together
Definition
1. Glycoproteins in glycocalyx act as an adhesive
2. Wavy contours of the membranes of adjacent cells fit together in a tongue and groove fashion
3. Special membrane junctions are formed
Term
Tight junctions
Definition
A series of integral protein molecules in plasma membranes of adjacent cells fuse together that make an impermeable junction (no molecules can pass through intercellular space)
:in digestive tract
Term
Desmosomes
Definition
Anchoring junctions: a mechanical coupling scattered like rivets along the sides of abutting cells that prevent their seperation
-Plaque (buttonlike thikening) are connected by linker protein filaments
-Reduce tension (in skin and heart)
Term
Gap Junctions
Definition
Communicating junctions allow ions and small molecules to pass from one cell to the next for intercellular communication
-Transmembrane proteins form pores to allow molecules to pass
-in electrically excitable tissues (heart and smooth muscle)
Term
Two types of channels in facilitated diffusion
Definition
1. leakage channels, always open
2. Gated channels, need a signal to open
Term
Name of water channels in plasma membrane
Definition
Aquaporins
Term
Tonicity
Definition
The ability of a solution to change the shape or tone of cells by altering their internal water volume
Term
Osmotic pressure
Definition
the tendency of water to move into the cell by osmosis
Term
Hydrostatic pressure
Definition
The back pressure exerted by water against the membrane
Term
Isotonic
Definition
A solution with the same solute concentration as that of the cytosol
Term
Hypertonic
Definition
A solution having greater solute concentration than that of the cytosol.
Term
Hypotonic
Definition
A solution having lesser solute concentration than that of the cytosol.
Term
Primary Active Transport
Definition
ATP-ADP gives energy for it.
-Calcium and hdrogen pumps
-Sodium-potassium pump (enzyme is Na+-K+ ATPase)
-Sodium outside, Potassium inside, they switch over in transport
Term
Secondary active transport
Definition
-Contransport (moves more than one substance at a time
-Symport system: 2 substances same direction
-Example: Na+ moves with glucose into the cell, Na+ can then be used for Primary AT
- Antiport system: 2 substances opposite directions
Term
Vesicular Transport (3 types)
Definition
Transport of large particles, macromolecules, and fluids across plasma membranes
-Requires cellular energy (ATP)
-Exocytosis transport out of cell
-Endocytosis transport into cell
-Transcytosis transport into, across, and then out of cell
(Protein coated vesicle goes in, loses protein coat to out of cell, combines with a sorting vesicle, membrane parts go out of cell in transport vesicle, then eaten by lysosome or contents go out the other side of the cell
Term
Phagocytosis (eating)
Definition
Pseudopods engulf solids and bring them into cell's interior, it combines with a lysosome and then is digested. the extra parts leave the cell by Exocytosis
Term
Pinocytosis (drinking)
Definition
Plasma membrane infolds, bringing extracellular fluid and solutes into interior of the cell
Term
Exocytosis
Definition
1. Membrane bound vesicle moves to Plasma membrane
2. Vesicle and P.M. fuse and a pore pops oben
3. v-SNAREs and t-SNAREs (proteins) bind
4. Vesicle contents are released
Examples: Hormone and mucus secretion, neurotransmitter release, ejection of wastes
Term
Resting Membrane Potential
Definition
Voltage measured in resting state of cells -50 to -100mV
-K is leaked making cell neg, but it comes back in because it is attracted to the neg
Term
Microvilli
Definition
Fingerlike extensions of plasma membrane
-increase surface area for absorption and makes it easier
-core made of actin filaments for stiffening
Term
Extracellular Materials (3)
Definition
1. Body fluids (interstitial fluid, blood plasma, cerebrospinal fluid)
2. Cellular secretions (intestinal and gastric fluids, saliva, mucus, serous fluids)
3. Extracellular matrix (abundant jellylike mesh containing proteins and polysaccharides in contact with cells)
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