Term
|
Definition
| response to an injury or destruction of tissues |
|
|
Term
|
Definition
1. infection
2. trauma
3. physical/ chemical agents
4. tissue necrosis
5. immune rxns
6. foreign bodies |
|
|
Term
|
Definition
1.redness (rubor)
2. heat (calor)
3. swelling (tumor)
4. pain (dolor)
5. loss of function (function laesa) |
|
|
Term
| Tissue that inflammation occurs |
|
Definition
loose/areolar connective tissue
tissue w/ external openings |
|
|
Term
|
Definition
main participant in inflammatory response
normal site with cells bound for tissue space |
|
|
Term
|
Definition
composed of endothelial cells
-exchange oxygen, nutrients, and waste |
|
|
Term
|
Definition
| responsible for formation of tissue fluid |
|
|
Term
| Vascular Acute Inflammation |
|
Definition
Vasodilation: increased blood flow and vascular permeability
-blood pressure++, proteins escape leads to redness, heat, swelling |
|
|
Term
| Cellular Acute Inflammation |
|
Definition
| Leukocytes move in aka exudate formation |
|
|
Term
|
Definition
| high protein content, pus formation |
|
|
Term
|
Definition
| increased blood flow, capillaries and venules dilate |
|
|
Term
|
Definition
| low protein, blister formation; causes blood to clot |
|
|
Term
|
Definition
mild injury: transudate
fluid only able to escape |
|
|
Term
| Purulent/ Suppurative Inflammation |
|
Definition
more severe: exudate w/ neutrophils
pus.. cyst may form |
|
|
Term
|
Definition
| great intensity: red blood cells escape |
|
|
Term
|
Definition
| movement of fluid in between compartments |
|
|
Term
|
Definition
| fluid, flow rate decreases, rbcs aggregate, wbcs move outward |
|
|
Term
|
Definition
| wbc in contact with endothelium |
|
|
Term
|
Definition
| wbc stay at surface of endothelium; makes it easier to attach to injury site |
|
|
Term
|
Definition
|
|
Term
|
Definition
PMN, peak 12-24 hrs after injury
survive for a short time |
|
|
Term
|
Definition
macrophages in tissue space, peak after 2/3 days
chemotactic agents attract |
|
|
Term
|
Definition
| Direct migration of a wbc to a region |
|
|
Term
|
Definition
1. recognize and attach
2. engulfment
3. killing |
|
|
Term
|
Definition
|
|
Term
|
Definition
| reduces free iron necessary for mitosis |
|
|
Term
|
Definition
| kills wbc and inhibit chemotaxis |
|
|
Term
|
Definition
| makes binding of opsonins difficult due to carbohydrate coating |
|
|
Term
|
Definition
vasodilation, released from mast cells and platelets
increase vascular permeability |
|
|
Term
|
Definition
| released from platelets... vasodilation |
|
|
Term
|
Definition
|
|
Term
|
Definition
vasodilation, increased permeability
ibuprofen, advil etc |
|
|
Term
|
Definition
| reduces release of serotonin and histamine |
|
|
Term
| Platelet-activation factor |
|
Definition
basophils and mast cells
platelet aggregation and degranulation
wbc activation |
|
|
Term
|
Definition
synthesized in liver
triggered by Hageman factor- cascade |
|
|
Term
|
Definition
|
|
Term
|
Definition
| increased permeability, responsible for pain |
|
|
Term
|
Definition
Membrane attack complex (MAC):
punch holes in membranes of microorganisms |
|
|
Term
|
Definition
infection of lymph nodes
seen more in children |
|
|
Term
|
Definition
| infection of lymph vessels |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Negatives of excessive inflammation |
|
Definition
1. Pain
2. Swelling
3. Tissue Damage-- frustrated phagocytosis |
|
|
Term
|
Definition
| + mast cells that lead to degranulation |
|
|
Term
|
Definition
|
|
Term
|
Definition
| slow healing process, infection control |
|
|
Term
| Macrophage-activating factor |
|
Definition
| keep macrophages at site of injury |
|
|
Term
| migration inhibitory factor |
|
Definition
| efforts focused at the site of injury |
|
|
Term
| Non specific chronic inflammation |
|
Definition
| more common, diffuse accumulation of macrophages and lymphocytes |
|
|
Term
| granulomatous inflammation |
|
Definition
granuloma
epitheliod cells: transformed macrophage--more cytoplasm, granulated |
|
|
