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Chapter 2
Single-Gene inheritance
29
Biology
Undergraduate 2
09/14/2011

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Term
two concepts of a gene
Definition
a unit of inheritance (phenotype) and a piece of DNA (genotype)
Term
nucleosome
Definition
when the DNA is wrapped around a histone
Term
heterochromatin
Definition
dense chromatin
Term
selfing
Definition
allowing pollen from a flower to fall on its own stigma
Term
crossing
Definition
pollen transferred to another organism
Term
single gene segregation
Definition
when the F1 yellow seed was self pollinated, it created a 3:1 ratio. when F1 yellow was crossed with a green, it produced a 1:1 ratio
Term
mendel's law of equal segregation
Definition
the two members (alleles) of a gene pair segregate from each other in meiosis; each gamete has an equal probablity of obtaining either member of the gene pair
Term
independent assortment
Definition
unlinked or distantly linked segregating gene pairs assort independently at meiosis
Term
ratios diagnostic of single-gene inheritance
Definition
1:1, 3:1 and 1:2:1
Term
synaptonemal complex
Definition
holds together two bivalent chromosomes; forms between the inner two chromatids
Term
tetrad analysis
Definition
used in fungi; chromatid ends up where it would if you draw out meiosis
Term
homozygous dominant
Definition
two copies of the dominant form of the allele
Term
haploinsufficient genes
Definition
one copy of the wild type allele is not enough
Term
haplosufficient genes
Definition
the wild type copy is sufficient to produce the wild type phenotype
Term
co-dominance
Definition
each allele gives a certain degree of product that are both needed to exhibit the phenotype
Term
genes recessiveness occurs through
Definition
haplosufficient genes
Term
genes dominance occurs through
Definition
haploinsufficient
Term
chromatograms
Definition
sequenes generated on a computer based upon sequencing traces
Term
homeotic mutants
Definition
rather than losing the organ all together, you converted them into some other part
Term
principles of inheritance can be applied in two directions
Definition
inferring genotypes from phnotypic ratios and predicting phenotypic ratios from parents of known genotype
Term
sex linked inheritance
Definition
usually shows different phenotypic ratios in two sexes of progeny as well as different ratios in reciprocal crosses
Term
autosomal recessive disorders
Definition
equally males and females; appearance of the disorder in a progeny with unaffected parents
Term
autosomal dominant disorder
Definition
progeny are males and females; appears in every generation
Term
examples of autosomal dominant
Definition
polydactyly and picbald spotting
Term
autosomal polymorphisms
Definition
two or more naturally occurring phenotypes; segregate as a single genetic locus with dominant or recessive alleles
Term
dimorphism
Definition
two morphs; most simple type of polymorphism; ex: tasters vs non-tasters
Term
x-linked recessive disorders
Definition
many more males than females show the phenotype; non of offspring ofm ales show the phenotype but daughters are carriers
Term
examples of x linked recessive disorders
Definition
red-green color blindness, hemophilia, duchenne muscular dystrophy, testicular feminization
Term
x-linked dominant disorders
Definition
affected males pass on the condition to all their daughters but none of their sons;
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