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chapter 25
Mr.Moulder Metabolism
10
Biology
Undergraduate 2
05/18/2012

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Term
Lipoprotein
Definition
- A water soluble molecule made up of protein and lipid which allows for transport in the blood.
Term
Chilomicron
Definition
- Formed in the mucosal cells of the Small Intestine, which transports dietary lipids to hepatocytes and adipocytes.
Term
Very low-density lipoprotein (VLDL)
Definition
- Formed in hepatocytes. Have a low protein content. A key function of VLDLs is to transport triglycerides to adipocytes for storage, and to muscle for ATP production. Become LDLs after depositing TG in adipocytes.
Term
Low-density lipoprotein (LDL)
Definition
- These are approx. 50% cholesterol. These deliver cholesterol and other lipids to body cells (for cell membrane repair, hormone production, bile salts production.
- Excess LDLs are deposited in arteries forming atherosclerotic plaques.
- Known as "bad cholesterol".
Term
High-density lipoprotein (HDL)
Definition
- Have a high protein content. These remove excess cholesterol from cells then transport it to the Liver.
- Known as "good cholesterol".
Term
Diabetes Mellitus
Definition
- A group of disorders associated with the ability to produce or use Insulin.
- Leads to high blood glucose, and possibly glucosuria.
- Causes Polyuria, Polydipsia and Polyphagia.
- With no Insulin to get glucose into cells, the cells rely on beta oxidation for energy.
- Ketosis follows which leads to ketoacidosis of the blood (lowered pH).
Term
Diabetes Mellitus
Definition
- A group of disorders associated with the ability to produce or use Insulin.
- Leads to high blood glucose, and possibly glucosuria.
- Causes Polyuria, Polydipsia and Polyphagia.
- With no Insulin to get glucose into cells, the cells rely on beta oxidation for energy.
- Ketosis follows which leads to ketoacidosis of the blood (lowered pH).
Term
Lipolysis
Definition
- The breakdown of Triglycerides into fatty acids and cholesterol.
- Glycerol is incorporated into glycolysis.
Term
Beta oxidation
Definition
- Occurs in the matrix of the Mitochondria, two carbons are removed at a time then attached to Coenzyme A to form Acetyl CoA. This is fed into the Krebs cycle.
Term
Ketosis
Definition
- Increased ketone bodies in the blood, caused by excessive beta oxidation.
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