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Chapter 23 Part 2: Human Microbiota
From Microbiology Textbook NMSU
13
Microbiology
Undergraduate 3
05/02/2012

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Term
Bradykinin
Definition
secreted by damaged tissue, promotes extravasation, stimulates mast cells to degranulate and release histamine
Term
prostoglandin
Definition

stimulates nerve endings; signals itching and pain

 

supressed by Tylenol

Term
phagosome-lysosome fusion
Definition
results in:
oxygen-independent killing pathways
oxygen-dependent killing pathways 
Term
oxygen-independent killing pathway
Definition
lysozyme, lactoferrin and defensins
Term
oxygen-dependent killing pathway
Definition
superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals, reactive nitrogen intermediates (NO, NO2-, and NO3-)
Term
oxidative burst
Definition
destroys pathogens, caused by oxygen-independent and oxygen-dependent killing pathways
Term
lysozyme
Definition
destroys peptidoglycan
Term
phagocytes
Definition
avoid attacking host cells; stops engulfment
Term
innate defenses
Definition
interferons
Term
interferons
Definition

low-molecular-weight cytokines; host specific action, not virus-specific

 

interfere with viral infection

Term
natural killer cells
Definition
immune cell that destroys our cells when they are infected or have gone bad (cancerous)
Term
MHC class 1 antigens
Definition
healthy cells
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