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Chapter 2 & 3
Objectives
42
Physiology
Undergraduate 2
02/07/2011

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Term
Amphipathic
Definition
consists of two parts (polar + nonpolar region)
Term
lipophilic
Definition
soluble in lipid, nonpolar
Term
lipophobic
Definition
not soluble in lipid, polar
Term
Polar molecule
Definition
Contains significant number of polar bonds (unequal sharing of electrons)
Term
Four classes of organic molecules
Definition
Carbs, proteins, lipids, nucleic acids
Term
Carbohydrates
Definition
hydrophilic, sweet
monosaccharide- glucose
disaccharide- sucrose
polysaccharid- glycogen
Term
Proteins
Definition
macromolecules of amino acids
Term
lipids
Definition
hydrophobic, fatty acid triglycerides, phospholipids, steroids (cholesterol)
Term
Nucleic Acids
Definition
DNA & RNA, genetic info
Term
Functions of proteins
Definition
structure, enzymes (catalysts), transport of lipophilic solutes (carriers), receptors for chemical messengers, antigens (immune system)
Term
Acidic
Definition
ph<7
Term
Alkaline
Definition
ph>7
Term
pH of interstitial fluid
Definition
7.4
Term
ph of intracellular fluid
Definition
7.0-7.2
Term
Cytoplasm
Definition
region of cell interior to outside of nucleus
Term
Cytosol
Definition
intracellular fluid that surrounds cell organelles and nucleus
Term
Cell membrane
Definition
composed of phospholipid bilayer. Everycell is surrounded by a plasma membrane (often with proteins embedded)
Term
Function of cell membrane
Definition
regulate passage of substances in & out, detect chemical messengers at surface, line adjacent cells and anchor cells to extracellular matrix
Term
Nucleus
Definition
transmits and expresses genetic info
Term
ribosomes
Definition
sites of protein synthesis
Term
Endoplasmic reticulum (rough)
Definition
attached ribosomes, involved in packaging of proteins to be secreted by cell/distributed to other organelles
Term
Endoplasmic reticulum (smooth)
Definition
site of lipid synthesis and calcium accumulation/release
Term
Golgi apparatus
Definition
modifies and sorts proteins synthesized on rough ER and packages them into secretory vesicles
Term
Endosomes
Definition
membrane bound vesicles that fuse with vesicles derived from plasma membrane and bud off vesicles that travel to other cell organelles
Term
Mitochondria
Definition
consume oxygen and produce carbon dioxide in chemical processes that transfer energy to the top
Term
Lysosymes
Definition
digest particular matter that enters the cell
Term
peroxisomes
Definition
use oxygen to remove H from organic molecules to form hydrogen peroxide
Term
Types of cell junctions
Definition
desmosomes, tight junctions, gap junctions
Term
Desmosomes
Definition
used where strength is needed, connected by rivets using cadherin
Term
Tight junctions
Definition
block gap between cells so material can only pass through cells (important in capillaries in blood brain barrier)
Term
Gap junctions
Definition
allows diffusion of adjacent cells via the pipe like connection between cells (important in heart muscle for simultaneous contraction)
Term
Membrane component most important in special functions of membrane?
Definition
Proteins: determine specialization such as glycoproteins for blood type and specialization of various membranes like neurons from salivary glands
Term
Affinity
Definition
strength with which ligands bind to its binding site
Term
Specificity
Definition
ability of binding site to react with only one or limited number of types of molecules
Term
Saturation
Definition
occupation of all available binding sites by their ligand
Term
anabolism
Definition
cellular synthesis of organic molecules
Term
catabolism
Definition
cellular breakdown of organic molecules
Term
metabolism
Definition
chemical reactions that occur in a living organism
Term
Law of mass action
Definition
An increase in reactant concentration causes a chemical reaction to proceed direction of product formation (vice versa occurs)
Term
Enzymes affect the rate of chemical reaction?
Definition
enzymes speed up the rate of a chemical reaction by lowering activation energy
Term
Enzymes effect equilibrium?
Definition
Enzymes do not change the equilibrium but just increase the speed at which equilibrium is reached
Term
Why do cells need ATP?
Definition
for energy to carry out functions/actions
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