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Chapter 16
The Molecular Basis of Inheritance
18
Biology
Not Applicable
05/06/2005

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Term
transformation
Definition
change in genotype and phenotype due to the assimilation of external DNA by a cell
Term
bacteriophages
Definition
viruses that infect bacteria
Term
double helix
Definition
two stranded
Term
semiconcervative model
Definition
when a double helix replicates each of the two daughter molecules will have one old strand derived from the parent molecule and one newly made strand
Term
origins of replication
Definition
where replication of DNA molecule begins
Term
replication fork
Definition
y-shaped region where new strands of DNA are elongating
Term
DNA polymerase
Definition
enzymes that catalyze new DNA at a replication fork
Term
leading strand
Definition
polymerase nestles in the replication fork, moving along the template strand as the fork progresses
Term
lagging strand
Definition
when polymerase must work along the template away from the replication fork
Term
DNA ligase
Definition
enzyme that joins okazaki fragments into a single DNA strand
Term
primer
Definition
original, preexisting chain
Term
primase
Definition
enzyme that joins RNA nucleotides to make the primer
Term
helicase
Definition
enzyme that untwists the double helix at the replication fork separating the two old strands
Term
mismatch repair
Definition
DNA repair mechanism; fixes mistakes that are made when DNA is copied
Term
nuclease
Definition
DNA cutting enzyme
Term
excision repair
Definition
type of repair that involves filling the gap are a DNA polymerase and ligase
Term
telomeres
Definition
DNA consists of multiple repetitions of one short nucleotide sequence
Term
telomerase
Definition
special enzyme that catalyzes the lengthening of telomeres
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