Term
|
Definition
Receptor Type: Cholinergic - Nicotinic
Major Locations: All ganglionic neurons, adrenal medullary cells, neuromuscular junctions of skeletal muscle
Effect of binding: Excitation/Stimulation |
|
|
Term
|
Definition
Receptor Type: Cholinergic - Muscarinic
Major locations: All parasympathetic target organs
Effect of binding: Excitation/stimulation |
|
|
Term
|
Definition
Receptor type: Adrenergic - B1
Major location: Heart
Effect of binding: Stimuation |
|
|
Term
|
Definition
Receptor Type: Adrenergic - Beta 2
Major Locations: Lungs, blood vessels
Effect of binding: Inhibitory (dilates blood vessels and bronchioles) |
|
|
Term
|
Definition
Receptor Type: Adrenergic - Beta 3
Major Locations: Adipose tissue
Effect of binding: Simulates |
|
|
Term
|
Definition
Receptor Type: Adrenergic - Alpha 1
Major Locations: Blood Vessels (sympathetic target organs except heart)
Effect of binding: Simulates (constricts blood vessels and visceral sphincters, dilates pupils. |
|
|
Term
|
Definition
Receptor Type: Adrenergic - Alpha 2
Major Locations: Membrane of adrenergic axon terminals
Effect of Binding: Inhibits release of NE from adrenergic terminals, inhibits insulin, promotes clotting. |
|
|
Term
|
Definition
Parasympathetic: constricts pupil and bulges lens for close vision
Sympathetic: dilates pupil and flattens lens for far vision |
|
|
Term
| Glands (nasal, lacrimal, gastric, pancreas) |
|
Definition
Parasympathetic: Stimulates secretions
Sympathetic: inhibits secretion, vasoconstricts blood vessels supplying glands |
|
|
Term
|
Definition
Parasympathetic: stimulates secretion of watery saliva
Sympathetic: stimulates secretion of thick, viscous saliva |
|
|
Term
|
Definition
Parasympathetic: No effect
Sympathetic: stimulates sweating |
|
|
Term
|
Definition
Parasympathetic: No effect
Sympathetic: Stimulates medulla cells to secrete NE or epinephrine. |
|
|
Term
|
Definition
Parasympathetic: No effect
Sympathetic: stimulates contraction |
|
|
Term
|
Definition
Parasympathetic: decreases rate
Sympathetic: Increases rate and force of beat |
|
|
Term
|
Definition
Parasympathetic: contraction of smooth muscle of bladder
Sympathetic: Casuses relaxation of smooth muscle of bladder |
|
|
Term
|
Definition
Parasympathetic: constricts bronchioles
Sympathetic: dilates bronchioles |
|
|
Term
|
Definition
Parasympathetic: Excites (constricts to expel bile)
Sympathetic: inhibits (relaxes) |
|
|
Term
|
Definition
Parasympathetic: Increase glucose uptake from blood
Sympathetic: Stimulates release of glucose to blood |
|
|
Term
|
Definition
Parasympathetic: No effect
Sympathetic: Promotes renin release, |
|
|
Term
|
Definition
Parasympathetic: erection
Sympathetic: ejaculation/contraction |
|
|
Term
|
Definition
Parasympathetic: no effect
Sympathetic: constriction |
|
|
Term
|
Definition
Parasympathetic: no effect
Sympathetic: increases coagulation |
|
|
Term
|
Definition
Parasympathetic: no effect
Sympathetic: increases metabolic rate |
|
|
Term
|
Definition
Parasympathetic: no effect
Sympathetic: stimulates fate breakdown |
|
|
Term
| Nicotinic agents (Nicotine) |
|
Definition
| Nicotinic receptors on all ganglionic neurons, stimulates sympathetic effect |
|
|
Term
| Parasympathomimetic agents |
|
Definition
Mimics effect of ACH, enhances parasympathetic effect.
Pilocarpine, glaucoma |
|
|
Term
|
Definition
bind to the enzyme ACHe that degrades ACH prolonging the effect of ACH.
Neostigmine, Sarin |
|
|
Term
|
Definition
adrenergic receptors, enhances sympathetic activity by increasing NE release or binding to adrenergic receptors.
Albuterol, ashtma |
|
|
Term
|
Definition
Adrenergic receptors, decrease sympathetic activity by blocking adrenergic receptors or inhibiting NE release
Propranolol, hypertension.
Beta blockers, decreasing heart rate and blood pressure |
|
|
