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chapter 13
Spinal Cord and Spinal Nerves
64
Biology
Undergraduate 2
03/11/2012

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Term
Spinal Cord Anatomy
Definition
- extends from Foramen Magnum to the level of the disk betweenL1/L2 vertebrae
- provides nervous pathways for nerve impulses between thePeripheral Nervous System and the Brain
- provides simple integrative functions (reflexes)
- 31 pair of spinal nerves come off of the cord to exitthrough the intervertebral foramen
Term
Dura Mater
Definition
- outer most layer
- anchors the meninges with in the spinal canal
- Epidural Space = lies outside the Dura that is filledwith fat and other connective tissues
Term
Epidural Space =
Definition
lies outside the Dura that is filledwith fat and other connective tissues
Term
Arachnoid Mater
Definition
- middle layer
- Subdural Space = lies outside of the arachnoid mater,contains interstitial fluid (lymph)
Term
Pia Mater
Definition
- covers the surface of the Brain and Spinal Cord
- Subarachnoid Space = lies outside of the Pia, containsCerebral Spinal Fluid (CSF)
Term
Subdural Space =
Definition
lies outside of the arachnoid mater,contains interstitial fluid (lymph)
Term
Fluid (CSF)
- Denticulate ligaments =
Definition
thickened Pia Mater thatprojects laterally to fuse with the Dura Mater, actsas a shock absorber
Term
Cervical Enlargement
Definition
- located between C4 and T1 vertebrae
- supplies nerves to the upper extremities
Term
Lumbar Enlargement
Definition
- located between T9 and T12 vertebrae
- supplies nerves to the lower extremities
Term
Conus Medullaris
Definition
- located between L1 and L2 vertebrae
- the end of the spinal cord
Term
Filum Terminale
Definition
- a fibrous band of Pia that extends from the Conus Medullaristo the Coccyx
- anchors the spinal cord
Term
Cauda Equina
Definition
- contains the nerves that leave the spinal cord then runinferiorly to exit from lower Intervertebral foramen
Term
Outer region
Definition
- is mostly white matter (myelinated fibers) providing nerveimpulse transmission to and from the Brain
- contains Posterior, Lateral and Anterior Columns
- Anterior Median Fissure
- Posterior Median Sulcus
Term
Inner region
Definition
- contains gray matter (non-myelinated neurons)
- provides integrative functions
- contains the Anterior and Posterior Horns
- Gray Commissure and Central Canal (filled with CSF)
Term
Posterior (Dorsal) Root
Definition
- made up of sensory neurons
- enters into the Posterior Horns
Term
Dorsal Root Ganglion =
Definition
contains the cell body's of thesensory neurons
Ganglion = a group of neuron cell bodies located outside theCNS
Term
Anterior (Ventral) Root
Definition
- made up of motor neurons
- exits from the Anterior Horns
Term
Spinal Nerve
Definition
- combination of Dorsal and Ventral Roots (a mixed nerve) thatcome together in the intervertebral foramen
Term
Sensory and Motor Tracts
Definition
- located in the Columns of the spinal cord
Term
Tract =
Definition
a bundle of nerve axons in the CNS (as opposed to anerve which is located outside the CNS)
Term
Lateral and Anterior Spinothalamic Tracts
Definition
- convey nerve impulses assoc. with pain, temperature change, deep pressure,
Term
Posterior Columns
Definition
- convey nerve impulses assoc. with proprioception (positionsense), discriminitive touch, two point discrimination,light pressure, vibration
Term
Reflex =
Definition
a fast, involuntary, unplanned sequence of actionsthat occur in response to a particular stimulus
Term
Reflex Arc
Definition
- the pathway followed by nerve impulses that produce a reflex
Term
Sensory Receptor
Definition
- a structure that responds to a specific stimulus
Term
Sensory Neuron
Definition
- carrys the nerve impulse to the spinal cord
Term
Integrating Center
Definition
- located in the gray matter
Term
Reflex Arc
- components:
Definition
a. Sensory Receptor
b. Sensory Neuron
c. Integrating Center
d. Motor Neuron
e. Effector
Term
Monosynaptic Reflex
Definition
- simplest type
- the sensory neuron synapses directly with themotor neuron
Term
Polysynaptic Reflex
Definition
- assoc. with two or more synapses
- assoc. with Interneuron (a neuron located in thespinal cord) involvement
Term
Motor Neuron
Definition
- carrys the nerve impulse away from the spinal cord.
Term
Effector
Definition
- the body part that responds to the nerve impulse
- ex. muscle
Term
Stretch Reflex
Definition
- causes contraction of skeletal muscle in response tostretching of the muscle
Term
Ipsilateral Reflex
Definition
- the sensory impulse enters the spinal cord on the same sidethat the motor impulse will leave (a monosynaptic reflex)
- ex. a stretch reflex
Term
Reciprocal Innervation
Definition
- this prevents conflict between opposing muscles
- while the agonist contracts the antagonist is inhibited
Term
Tendon Reflex
Definition
- leads to muscle relaxation when the stretch on tendons maylead to damage
Term
Flexor (Withdrawal) Reflex
Definition
- assoc. with withdrawal from a negative (painful) stimulus
Term
Intersegmental Reflex Arc
Definition
- the sensory impulse enters the spinal cord then ascends ordescends in the cord
Term
Crossed Extensor Reflex
Definition
- assoc. with extension of joints on one side of the bodywhile the flexors are contracting in the contralateralmuscle
Term
Contralateral Reflex Arc
Definition
- nerve impulses enter the cord, cross over in the GrayCommissure, then exit on the opposite side of the cord
Term
1. Endoneurium


2. Perineurium


3. Epineurium
Definition
1. - surrounds individual nerve fibers
2. - surrounds bundles of nerve fibers
- Fascicle = bundle of nerve fibers
3. - surrounds a group of fascicles = Nerve
- this layer is continuous with the Dura Mater of the spinalcord
Term
1. Endoneurium


2. Perineurium


3. Epineurium
Definition
1. - surrounds individual nerve fibers
2. - surrounds bundles of nerve fibers
- Fascicle = bundle of nerve fibers
3. - surrounds a group of fascicles = Nerve
- this layer is continuous with the Dura Mater of the spinalcord
Term
Dorsal Ramus
Definition
- innervates deep muscles and skin of the dorsal trunk
Term
Ventral Ramus
Definition
- innervates limb muscles, and skin of the extremitiesand the remaining trunk
Term
Ventral Ramus
Definition
- innervates limb muscles, and skin of the extremitiesand the remaining trunk
Term
Meningeal Branch
Definition
- reenters the spinal cord to supply innervation tospinal cord structures
Term
Rami Communicantes
Definition
- Autonomic Nervous System innervation
Term
Branch = Ramus (pl. Rami)
Definition
- the spinal nerves divide into branches after leaving the Intervertebral Foramen
Term
Branch = Ramus (pl. Rami)
parts:
Definition
Dorsal Ramus
- innervates deep muscles and skin of the dorsal trunk
b. Ventral Ramus
- innervates limb muscles, and skin of the extremitiesand the remaining trunk
c. Meningeal Branch
- reenters the spinal cord to supply innervation tospinal cord structures
d. Rami Communicantes
- Autonomic Nervous System innervation
Term
Plexus
Definition
- a network of nerves
- ventral rami
Term
Plexus
parts:
Definition
a. Cervical Plexus (C1 - C5)
- the Phrenic Nerve (C3 - C5) which innervates theDiaphragm
b. Brachial Plexus (C5 - T1)
- supplies innervation to the shoulder and upper limb
c. Lumbar Plexus (L1 - L4)
- supplies part of the abdominal walls, externalgenitalia, and part of the proximal lower limb
d. Sacral Plexus (L4 - S4)
- supplies innervation to the lower limb
- Sciatic Nerve (L4 - S3) = largest nerve in the bodywhich is made up of two separate nerves (Tibial andCommon Fibular)
Term
Cervical Plexus (C1 - C5)
Definition
- the Phrenic Nerve (C3 - C5) which innervates theDiaphragm
Term
Brachial Plexus (C5 - T1)
Definition
- supplies innervation to the shoulder and upper limb
Term
Lumbar Plexus (L1 - L4)
Definition
- supplies part of the abdominal walls, externalgenitalia, and part of the proximal lower limb
Term
Sacral Plexus (L4 - S4)
Definition
- supplies innervation to the lower limb
Term
Sciatic Nerve (L4 - S3) =
Definition
largest nerve in the bodywhich is made up of two separate nerves (Tibial andCommon Fibular)
Term
Sciatic Nerve (L4 - S3) =
Definition
largest nerve in the bodywhich is made up of two separate nerves (Tibial andCommon Fibular)
Term
Sciatica =
Definition
inflammation of the Sciatic Nerve
- pain may follow the nerve all the way down thefoot
Term
Intercostal Nerves
Definition
- ventral rami
- innervate the intercostal spaces
Term
Dermatomes p. 446
Definition
- the area of the skin that provides sensory input through onepair of spinal nerves or Cranial nerve 5
Term
Shingles "Singles with Shingles"
Definition
- an infection caused by the Herpes Zoster virus
- this virus also causes Chicken Pox
- this virus remains dormant in the Dorsal Root Ganglion
- can cause skin eruptions along the infected nerve
- lesions are acutely painful
Term
Poliomyelitis = Polio
Definition
- caused by the Poliovirus
- causes fever, severe headaches and muscle aches, weakness
- can cause paralysis
- virus can destroy motor neuron cell bodys in the AnteriorHorn
- death associated with Respiratory or Heart failure
- the virus is often transmitted by fecal-oral contamination(and Yeah its just what you think!)
Term
Neuritis
Definition
- inflammation of one or more nerves
- causes pain along the pathway of the involved nerves
- ex. Sciatica = neuritis of the Sciatic nerve
Term
Amyotrophic Lateral Sclerosis (ALS)
Definition
- "Lou Gehrig's Disease"
- disease that effect nerve cell bodies in the Anterior Hornand Brain (i.e. motor neurons)
- leads to progressive muscle degeneration
- person often retains most of their sensory stimulus
- often begins in mid-life
- a chronic, progressive disease
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