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Chapter 12 Vocabulary
Cell Division
45
Biology
11th Grade
02/08/2008

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Term
cell division
Definition
reproduction of cells
Term
cell cycle
Definition
the life of the cell from its origin in the division of a parent cell until its own division into two cells
Term
genome
Definition
a cell's DNA or genetic information
Term
chromosomes
Definition
a thread-like gene carrying structure found in the nubleus
Term
somatic cells
Definition
all body cells except the reproductive cells
Term
gametes
Definition

reproductive cells

Term
chromatin
Definition
the DNA-protein complex which maintains structure of the chromosome and helps control activity of the genes
Term
sister chromatids
Definition
replicated forms of a chromosome joined together by the centromere and eventually separated during mitosis or meisosis II
Term
centromere
Definition
specialized region which joins the sister chromatids together
Term
cytokinesis
Definition
the division of the cytoplasm
Term
meiosis
Definition
variation of cell division of the cytoplasm
Term
mitotic (M) phase
Definition

includes both mitosis and cytokinesis

Term
interphase
Definition
the period in the cell when the cell is not dividing
Term
G1 phase
Definition
first phase of the interphase
Term
S Phase
Definition
period of interphase
Term
G2 phase
Definition
second phase "gap" of interphase
Term
prophase
Definition
1st subphase of mitosis; chromatin is condensing and mitotic spindle begins to form; nucleus is still in tact
Term
prometaphase
Definition
2nd subphase of mitosis; discrete chromosomes with sister chromatids appear, nuclear envelope fragments, and spindle microtubules attach to the kinetochores of the chromosomes
Term
metaphase
Definition
3rd subphase of mitosis; spindle is complete and the chromosomes are all aligned at the metaphase plate
Term
anaphase
Definition
4th subphase of mitosis; chromatids of each chromosomes have separated and the daughter chromosomes are moving to the poles of the cell
Term
telophase
Definition

5th subphase of mitosis; daughter nuclei are forming and cytokinesis has typically begun

Term
asters
Definition
radial arrays of microtubules that extend from the centrosomes
Term
kinetochore
Definition
a specialized region of the centromere that links each sister chromatid to the mitotic spindle
Term
metaphase plate
Definition
an imaginary plane that is equidistant between the spindles two poles
Term
mitotic spindle
Definition
an assemblage of microtubules and associated proteins that is involved in the movements of chromosomes during mitosis
Term
centrosome
Definition
a nonmembranous organelle that functions throughout the cell cycle to organize the cell's microtubules
Term
cleavage
Definition
the process of cytokinesis in animal cells, characterized by pinching of the plasma membrane
Term
cleavage furrow
Definition
the first sign of cleavage in an animal cell, near the old metaphase plate
Term
cell plate
Definition
a double membrane across the midline of a dividing plant cell, between which the new cell wall forms during cytokinesis
Term

binary fission

Definition
process by which prokaryotes (bacteria) reproduce
Term
origin of replication
Definition
sites where the replication of a DNA molecule begins
Term
cell cycle control system
Definition
a clinically operating set of molecules in the cell that both triggers and coordinates key events in the cell cycle
Term
checkpoint
Definition
a critical control point where "stop" and "go ahead" signals can regulate the cycle
Term
G0 phase
Definition
nondividing state a cell enters when it does not recieve a "go ahead" signal at G1 checkpoint
Term
cyclin
Definition
a protein that gets its name from its cyclically fluctuating concentration in the cell
Term
cyclin-dependent kinases (Cdks)
Definition
a protein kinase that is active only when it is attached to a particular cyclin
Term

MPF

Definition
a protein complex required for a cell to progress from late interphase to mitosis
Term
growth factor
Definition
a protein released by certain body cells that stimulates other cells to divide
Term
density-dependent inhibition
Definition
a phenonmenon in which crowded cells stop dividing
Term
anchorage dependence
Definition
to divide, an animal cell must attach to a substratum (cultur jars)
Term
transformation
Definition
the process that converts a normal cell to a cancer cell
Term
tumor
Definition
a mass of abnormal cells within otherwise normal tissue
Term
benign tumor
Definition

when these abnormal cells remain at the original site

Term
malignant tumor
Definition
tumor that becomes invasive enough to impair the functions of one or more organs
Term
metastasis
Definition
the spread of cancer cells to locations distant from their original site
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