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Chapter 11
Cell Communication
17
Biology
Not Applicable
05/06/2005

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Term
signal-transduction pathway
Definition
series of steps by which a signal on a cell's surface is converted into a specific cellular response
Term
local regulator
Definition
a substance that influences cells in the vicinity
Term
hormones
Definition
chemicals for signaling at greater distances
Term
ligand
Definition
small molecule that specifically binds to a larger one
Term
G-protein-linked receptor
Definition
plasma-membrane receptor that works with the help of a G-protein
Term
G-protein
Definition
functions as a switch that is on or off depending on which of two guanine nucleotides is attatched, GDP or GTP
Term
tyrosine kinase
Definition
enzyme that catalyzes the transfer of phosphate groups from ATP to amino acid tyrosine on a substate protein
Term
tyrosine-kinase receptors
Definition
membrane receptors that attach phosphates to protein tyrosines
Term
ligand-gated ion channels
Definition
membrane receptors of chemical signals
Term
protein kinase
Definition
enzyme that transfers phosphate groups from ATP to a protein
Term
protein phosphates
Definition
enzymes that remove phosphate groups from proteins
Term
second messengers
Definition
small, nonprotein, water-soluble molecules or ions
Term
cyclic AMP (cAMP)
Definition
compound called cyclic adenosine monophosphate
Term
adenylyl cyclase
Definition
enzyme built into the plasma membrane that converts ATP to cAMP in response to an extracellular signal
Term
diacylglycerol (DAG)
Definition
second messenger
Term
inositol trisphosphate (IP3)
Definition
second messenger
Term
calmodulin
Definition
a Ca2+ binding protein present at high levels in eukaryotic cells
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