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Ch. 28 The Reproductive Systems
Anatomy
134
Anatomy
Undergraduate 3
04/13/2014

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Term
What is gynecology?
Definition
Study of female reproductive system
Term
What is urology?
Definition
Study of urinary system and male reproductive system
Term
What are gonads? What are the names for the male and female gonads?
Definition
Structures that produce gametes and hormones, male: testes, female: ovaries
Term
What are the purpose of ducts in the gonads? What are they called in the male and female?
Definition
Purpose is to transport/receive/store gametes, male: epididymus/ductus deferens, female: uterine tubes
Term
What is the purpose of accessory sex glands? What are the male and female sex glands?
Definition
Purpose is to support gamete survival, male: prostate/seminal vesicles/bulbourethral glands, female: paraurethral glands/greater vestibular glands
Term
What is the purpose of the copulatory organs? What are the male and female ones?
Definition
Purpose is to transfer gametes into female, male: penis, female: vagina
Term
What are the supporting structures for the male and female?
Definition
Male: scrotum, female: labia
Term
What is the scrotum, its purpose, and muscles involved?
Definition
Extension of abdominal cutaneous tissue, purpose is to conatin/support testes and thermoregulation, muscles are dartos which wrinkles skin/elevates testicles and cremaster which raise testes temperature
Term
Where does spermatogenesis occur?
Definition
Seminiferous tubules
Term
What are sertoli cells?
Definition
Blood-testis barrier, prevents immune response against spermatozoa since surface antigens are "foreign", nourish spermatocytes/spermatids/sperm, inhibin is located in the testes which inhibits FSH secretion to control speed/rate of spermatogenesis
Term
What are leydig cells?
Definition
Produce testosterone for male secondary sex charactersitics and spermatogenesis
Term
What is cryptorchidism?
Definition
Undescended testicle, increases risk for testicular cancer by 3-14%
Term
What is testicular torsion?
Definition
Peaks at 13-16 years, twisting of spermatic cord with pain in scrotum, emergency surgery required within 6 hrs
Term
What is testicular cancer?
Definition
Most common cancer in men b/w 20-35 years
Term
What is the epididymis?
Definition
Tightly coiled tubes, maturation and storage of sperm, acqure motility and ability to fertilize secondary oocyte, help propel sperm into vas deferens by peristalsis during sexual arousal
Term
What is the ductus deferens?
Definition
Vas deferens, extends from testes to urethra, storage and transport of sperm, sperm not ejaculated eventually reabsorbed, tubes cut/tied in vasectomy
Term
What is the ejaculatory duct?
Definition
Junction of seminal vesicle duct with ductus deferens, eject sperm and seminal vesicle secretions into urethra
Term
What is the urethra?
Definition

Surrounded by spongy tissue, carries both urine/semen

3 parts:

1. Prostatic urethra

2. Membranous urethra

3. Spongy urethra

Term
What are the seminal vesicles?
Definition
Paired at posterior of urinary bladder, alkaline/viscous fluid, prostaglandins/fibrinogen/fructose present
Term
What are the bulbourethral glands?
Definition
Located inferior to the prostate gland, size of peas, alkaline fluid which neutralizes acid, mucus
Term
What is the prostate gland?
Definition
Inferior to bladder, slightly acidic fluid, enzymes here such as fibrinolysin, PSA is a test for hypertrophy of the gland
Term
What is semen?
Definition
Volume in typical ejaculation is about 2.5 - 5 mL
Term
What is a circumcision?
Definition
Part or entire prepuce removed, cultural norm in some regions, has effect on sensations, lower risk of urinary tract infections
Term
When do the ovaries move into the pelvis?
Definition
During the 3rd month of fetal development
Term
What are the names for the outer and interior of the ovaries?
Definition

Outer: germinal epithelium

Interior: stroma

Term
What is the function of the ovaries?
Definition
Produce gametes and hormones
Term
What is the infundibulum?
Definition
First segment of uterine tubes, open to pelvic cavity
Term
What are the fimbriae?
Definition
Fingerlike projections that collect secondary oocyte
Term
What is the ampulla?
Definition
Usual site of conception
Term
What is the isthmus?
Definition
Place where the uterus joins
Term
What is an ectopic pregnancy?
Definition
Implantation outside of uterus, surgical abortion is only treatment, is life-threatening for mother
Term
What is the uterus?
Definition
Site of menstruation/fetal development, has size and shape of inverted pear
Term
What are the 3 layers of the uterus?
Definition

1. Endometrium - vascular

2. Myometrium - muscle

3. Perimetrium - part of visceral peritoneum

Term
What are the 3 regions of the uterus?
Definition

1. Fundus

2. Body

3. Cervix

Term
What is a PAP smear?
Definition
Detects abnormal precancerous cells, should be done annually
Term
What is a D&C?
Definition
Scrapes endometrium
Term
What is endometriosis?
Definition
Endometrial tissue outside of uterus, painful
Term
What is a hysterectomy?
Definition
Removal of uterus
Term
What is cervical cancer?
Definition
Human papilloma virus/genital warts/other STDs increase risk
Term
What are the different pathways of the vagina?
Definition
Menstrual flow, childbirth, receives penis during intercourse
Term
What are some characterstics of the vagina?
Definition
Pliable, elastic, rugae present, stratified squamous epithelium, dendritic cells transfer viruses such as HIV
Term
What are the parts of the vagina?
Definition

Fornix: expanded region around cervix

Hymen: thin layer of tissue partially blcoking vaginal orifice

Colposcopy: use microscope to examine cervix, acetic acid and Lugol's iodine applied to stain cervix, abnormal area identified often after PAP smear

Term
What does the vulva of the vagina contain?
Definition
Mons pubis and labia
Term
What is the mons pubis?
Definition
Pubic mound, cushions pubic symphysis
Term
What is the labia?
Definition

Majora - fatty folds, sebaceous and apocrine sudoriferous glands

Minora - medial, no pubic hair, sebaceous glands

Term
What are the female external structures?
Definition
Clitoris, vestibule, glands, and bulb of vestibule
Term
What is the clitoris?
Definition
Only function is sexual stimulation, erectile tissue, prepuce is where minora unite/covers clit
Term
What is the vestibule?
Definition
Region between minora, contains hymen and vaginal orifice and external urethral orifice
Term
What are the glands of the female reproductive?
Definition
Paraurethral for mucus, greater vestibular for mucus, lesser vestibular for mucus
Term
What is the bulb of vestibule?
Definition
Two elongated masses of erectile tissue, either side of vaginal orifice, engorges, squeezes penis during intercourse
Term
What is involved in a female circumcision?
Definition
Removal of clitoris and parts of labia minora, purpose is to reduce risk of adultery in some countries
Term
What are the mammary glands?
Definition
Amount of adipose tissue determines breast size except when lactating, size not related to milk volume production, contains alveoli which are milk-producing glands
Term
What is the areola?
Definition
Pigmented area around nipple, rich in sebaceous glands
Term
What are Cooper's suspensory ligaments?
Definition
Connective tissue strands that support breast, age and/strain cause ligaments to stretch
Term
What is breast development controlled by?
Definition
Estrogens and progesterone
Term
What is milk production/ejection controlled by?
Definition
Production stimulated by prolactin, ejection stimulated by oxytocin
Term
What events occur in the ovary/uterus during the menstrual phase (weeks 1-5)?
Definition

Ovaries: follicle development, secondary oocyte to edge of follicle

Uterus: lose blood/mucus/epithelial cells

Term
What events occur in the ovaries/uterus during the preovulatory phase (weeks 6-13)?
Definition

Ovaries: secondary follicle matures

Uterus: endometrial build up

Term
What events occur in the ovaries/uterus during the ovulation phase (week 14)?
Definition

Ovaries: ovarian follicle ruptures secondary oocyte, captured by fimbrae

Uterus: mittleschmerz, soft cervix, temp increase, cervix mucus thins

Term
What events occur in the ovaries/uterus during the postovulatory phase (weeks 15-28)?
Definition

Ovaries: luteal phase when corpus luteum develops

Uterus: secretory phase when endometrial is thickest for implantation

Term
What are the 4 phases of sexual intercourse?
Definition

1. Excitement

2. Plateau

3. Orgasm

4. Resolution

Term
What occurs in the male/female in the excitement phase?
Definition

Male: vasocongestion where penis is engorged with blood, cremaster muscle contracts which elevates testes, increase in HR/BP/breathing, myotonia which is increased muscular excitability

ย 

Female: vaginal lubrication, vasocongestion of clitoris/vagina/uterus/labia minora/nipples, increase in HR/BP/breathing, myotonia

Term
What happens in male/female during the plateau phase?
Definition

Male: few drops from bulbourethral glands may contain some sperm, increase in HR/BP/breathing, myotonia

ย 

Female: imminent orgasm when labia become larger, clitoris retracts, increase in HR/BP/breathing, myotonia, strong muscular contractions of distal third of vagina

Term
What happens in male/female during the orgasm phase?
Definition

Male: strong pleasure sensations, ejaculation which involves emission(movement of sperm from epididymis to penile urethra) and expulsion(semen out of urethra)

ย 

Female: status orgasmus, sustained orgasm up to 1 minute, rhythmic contractions of vagina/uterus/perineal muscles, strong sensations of pleasure

Term
What occurs in male/female in the resolution phase?
Definition

Male: loss of tumescence(limp), unable to obtain erectin for minutes to hours, genital tissues/HR/BP/breathing/muscle tone returns to normal state

ย 

Female: no refractory period, may return to plateau, or returns to normal levels

Term
What is surgical sterilization?
Definition
Failure rate of <0.5%, prevents fertilization by not allowing sperm/secondary oocyte to reach gamete of opposite gender, half of all vasectomies reversed produce antibodies which can prevent fertility
Term
How do hormonal methods of birth control work?
Definition
Prevent ovulation by inhibiting secretion of FSH/LH thus dominant follicle does not develop, make cervical mucus thicker, prevent implantation
Term
How does the pill work?
Definition
Uses estrogens and progesterone, cause menstrual flow to be between days 21 and 28, reduces menstrual cramps and flow, reduces risks for fibrocystic breast disease/ovarian and endometrial cancer, may experience 3-5 lb weight gain/breast enlargement/emotional changes, prevents ovulation and implantation
Term
What is the minipill?
Definition
Uses progesterone only, thickens cervical mucus
Term
How does the subcutaneous implant work?
Definition
Norplant/implanon, prevents ovulation and implantation
Term
How does the injection work?
Definition
Depo-Provera is what it's called, prevents ovulation and implantation
Term
How does the IUD work?
Definition
Prevents implantation by irritating endometrium, dangerous side effects such as pelvic inflammatory disease
Term
How does spermicide work?
Definition
Kill sperm by disrupting plasma membrane which prevents fertilization
Term
How do barrier methods work?
Definition
Provide physical barrier so that sperm and secondary oocyte cells do not come in contact with each other, prove some protection against STDs, examples are condoms/diaphragm/cervical cap/sponge
Term
How does the female condom work?
Definition
Extends 1" beyond labia, protects vulva and vagina, frequent slippage
Term
How do physiological/behavioral methods work?
Definition
Natural family planning, avoid intercourse or use other birth control method during times of fertility, does not work well in women with irregular menstrual cycles
Term
How does the rhythm method work?
Definition
Estimate ovulation by using calender, abstain from intercourse during days when pregnancy most likely to occur
Term
How does the sympto-thermal method work?
Definition
Measure body temp when first awaken in morning, 2ยบ spike when ovulation occurs
Term
How does the withdrawal method work?
Definition
Also called coitus interruptus, withdrawal of penis before ejaculation
Term
How do emergency contraceptives work?
Definition
Morning after pills, used after fertilization within 72 hours, RU-486 uses anti-progesterone which cause endometrium to shed and may cause excessive bleeding and can be taken up to 5 weeks after conception
Term
What is an induced abortion?
Definition
Drug induced using saline/prostaglandins, vacuum aspiration(suction)
Term
When does gender differentiation occur?
Definition
6-8 weeks of embryonic development, +SRY gene means testosterone and testoerone receptors are produced, -SRY gene means no testerone or receptors are produced
Term
What are the equivalent male/female structures?
Definition

Testes = ovaries

Sperm = ovum (2nd oocyte)

Scrotum = labia majora

Spongy urethra/penile skin = labia minora

Glans penis = clitoris

Prostate gland = paraurethral glands

Bublourethral glands = vestibular glands

Term
What is adrenarche?
Definition
Adrenal activity, causes growth spurt
Term
What is puberty in males?
Definition
Between ages 10-17, LH and FSH surge, testosterone levels elevate, testicles enlarge and begin producing sperm, penis enlarges, development of secondary sex characteristtics
Term
How does fertility in males change with aging?
Definition
Fertile into their 90+ years, slow decline in testosterone starting in 40s
Term
What is adrenarche in females?
Definition
Adrenal activity that leads to growth spurts
Term
What is menarche in females?
Definition
Happens at 13 years, LH and FSH surge and estrogen levels rise, secondary sex characteristics form and sexual organs mature
Term
What is premenopause?
Definition
Gradual decline in fertility
Term
What is menopause?
Definition
Ovaries less responsive to FSH and LH, hot flashes, perspiration, headaches, vaginal dryness, insomnia, depression, osteoporosis
Term
What is testicular cancer?
Definition
Adolescents to middle age is generally the age window, associated with cryptorchidism, signs/symptoms are palpated mass/pain, remove testis to treat
Term
What is prostatitis?
Definition
Associated with urethritis
Term
What is benign hypertrophy?
Definition
Common in males older than 60, blocks urine flow, surgery to treat
Term
What is prostate cancer?
Definition
Digital rectal exam/needle biopsy/ultrasound/PSA test to discover, treated by TURP/chemotherapy/radiation/hormone therapy, prevented by regular exam yearly for men less than 40 and annual PSA test for men greater than 50
Term
What is erectile dysfunction?
Definition
Erection not attained or sustained, caused by insufficient NO/chronic illness/vascular abnormality/medications/psychological factors/spinal cord injury, treated by viagra/counseling/penile pumps and implants
Term
What is infertility?
Definition
Low sperm count, obstructed sperm path, caused by x-rays/infections/high temperature/malnutrition/endocrine disorders, treated by artificial insemination/in-vitro fertilization/intrauterine insemination/gamete intrafallopian transfer
Term
What is amenorrhea?
Definition
Not having normal menstrual cycles, absence of menses, endocrine problem, congenital deformity, low body fat, stress
Term
What is dysmenorrhea?
Definition
Cramps, painful menses, prostaglandin-induced uterine contractions
Term
What is menorrhagia?
Definition
Excessive flow, endocrine problems, stress, fibroid uterine tumors, systemic illness
Term
What is premenstrual syndrome?
Definition
Postovulatory mental and/or physical distress, signs/symptoms include: weight gain, breast tenderness, pain, fatigue, fragile emotions, food cravings, irritability, mood swings
Term
What is toxic-shock syndrome?
Definition
Staphylococcus aureus, young females who use tampons or contraceptive sponge, symptoms include high fever/sore throat/memory loss/rash/flu-like symptoms, treatment by antibiotics
Term
What is endometriosis?
Definition
Endometrial growth outside of uterus, could be in ovaries/lymph nodes/outer uterine surface/abdominal organ surface, caused by menstrual backflow/developmental error, signs/symptoms include premenstrual or severe menstrual pain, diagnosis based on presence of pelvic pain/physical exam/laparoscopy, treated by hormone therapy/surgery/oophorectomy
Term
What is breast cancer?
Definition
Signs are lumps/orange peel texture/inverted nipple/discharge, risks include genetics/late or no pregnancy/previous breast cancer/radiation exposure/high fat diet/alcohol/smoking
Term
How is breast cancer diagnosed and treated?
Definition

Diagnosed by: self-exam each month, physical exam every 3 years, mammography every year if 40+ years, ultrasound, biopsy, thermography

Treated by: lumpectomy, mastectomy, chemotherapy, radiation therapy

Term
What is fibroadenoma?
Definition
Beningn breast tumor, found in young women, surgical removal
Term
What are ovarian cysts?
Definition
Fluid-containing sac in ovary, most common form of ovarian tumor, menstruating and post-menopausal women, surgery to treat
Term
What is infertility?
Definition
Inability to conceive, caused by ovarian disease/tubal obstruction/uterine abnormalities/hormone imbalance/autoimmune diseases, treatment depends on cause
Term
What is cervical cancer?
Definition
PAP smear/pelvic exam to detect, initial cervical dysplasia, progressive, linked to HPV/HSV-2, prevented by Gardasil, treated by excision/cauterizing/cryotherapy/radiation/chemotherapy
Term
What is pelvic inflammatory disease?
Definition

Bacterial infection of pelvic organs may lead to peritonitis, caused by STDs, symptoms/signs include: tenderness, fever, leukocytosis, cervical discharge, bacterial cultures

Responds to antibiotics, effects include infertility/ectopic pregnancy/pelvic pain

Term
What is vulvovaginal candidiasis?
Definition
Candida albicans, yeast infection, attacks GI and urogenital mucous membranes, opportunistic infection, signs/symptoms include vaginal itching/thick yellow yeasty discharge/pain, treated by oral/topical anti-fungal agents
Term
What are the 3 categories of STDs?
Definition

1. Parasites

2. Bacteria

3. Viruses

Term
Are STDs usually symptomatic? What does this mean?
Definition
No they are usually asymptomatic, this means they often go untreated
Term
What are characteristics of parasites and bacterial STDs?
Definition
Can be cured with use of topical treatments or antibiotics, damage to body cannot be reversed, if treated early some STDs will leave no lasting physical effects
Term
What are characteristics of viral STDs?
Definition
Affect body for life, some can be treated, some can resolve with time, no medical cures available to kill virus
Term
How are STDs prevented?
Definition
25% of Americans are infected with one or more STDs, not participating in activities that can result in exposure, condoms can reduce risk, minimize risk factors
Term
How is chlamydia caused?
Definition
Bacterial infection
Term
How is genital warts caused?
Definition
Viral infection
Term
How is gonorrhea caused?
Definition
Bacterial infection
Term
How is syphilis caused?
Definition
Bacterial infection
Term
How is scabies caused?
Definition
Parasite infection
Term
How is genital herpes caused?
Definition
Viral infection
Term
How is hepatitis B caused?
Definition
Viral infection
Term
How is trichomoniasis caused?
Definition
Protist infection
Term
How is HIV/AIDS caused?
Definition
Viral infection
Term
What is castration?
Definition
Testicle removal/orchectomy
Term
What is a culdoscopy?
Definition
Examination of internal female pelvic organs through incision in vagina
Term
What is a endocervical curettage?
Definition
Cervix dilated and cells scraped from endometrium of uterus, commonly called D & C
Term
What is hermaphroditism?
Definition
One individual possessing tissue of ovaries and testes
Term
What is hypospadias?
Definition
Displaced urethral opening
Term
What is leukorrhea?
Definition
Whitish/viscous discharge from vagina and uterine cavity
Term
What is an oophorectomy?
Definition
Removal of ovaries
Term
What is a salpingectomy?
Definition
Removal of fallopian tube
Term
What is vaginitis?
Definition
Inflammation of vaginal mucosa
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