Psoriasis

1. Genetic Factors are a contributor

2. sharply marginated and erythematous and surmounted by silvery scales

3.  Most patients with psoriasis have a limited number of fixed plaques, but there is great variation in clinical presentation

4.  epidermis is thickened as a result of elongation of rete ridges

5. Can occur everywhere but the scalp

1. consists of a papule or plaque with a central zone of epidermal necrosis surrounded by a rim of erythema.

2. Appearance of a Bull's Eye

3. The eruption is commonly brief and self-limited, but repetitive or generalized attacks can be disabling or even life threatening

4.  specific inciting agents recruit effector lymphocytes into the epidermis and papillarydermis

5.generally limited to the skin and mucous membranes 

6. Two types major and minor

1. blistering disease in which tense fluid-filled spaces develop within erythematous, inflamed skin

2.  develop because of detachment of the epidermis from the dermis (subepidermal vesiculation) as the result of a specific inflammatory reaction directed against structural proteins. 

3. generally a disorder of the elderly

4. Lesions are most commonly distributed on the extremities and lower trunk, but blisters can develop at any site 

1. an inflammatory disorder affecting small blood vessels of the skin that typically presents as an eruption of reddish or violaceous papules, a pattern known as palpable purpura

2.  The lesions develop in crops, and individual papules persist for a few days or weeks and generally less than a month

3. can develop at any age, and the incidence is equal in both sexes

4. Bacterial, mycobacterial, and viral infections can all trigger bouts, but poststreptococcal and poststaphylococcal eruptions are most common.

1. an eruption, usually pruritic, caused by a specific immune-mediated reaction to a substance that has touched the skin

2. The acute phase is characterized by erythematous papules, vesicles, and bullae confined to the area of primary contact of the "allergen" 

3. Often the blisters break down and result in weeping and formation of a yellowish crust.

4. poison ivy and poison oak are among the most common causes of this

1. inflammatory process that occurs in the fat of the subcutis

2. is the most common form of panniculitis, presenting most often with tender red nodules on the anterior lower legs

3. The number of lesions is variable, but typically a dozen or more lesions may be present at onset. 

4. Women seem especially susceptible to its development, and there is an adult female–male predominance of 3:1 

5. tends to occur on the anterior shins but may involve the thighs, the extensor forearms, and, rarely, the trunk

1. is an enigmatic systemic disease with a hugely variable clinical spectrum ranging from mild asymptomatic skin papules to life-threatening lung disease. Lesions are often red-brown dermal papules or nodules that may occur anywhere on the cutaneous surface but have a special predilection for the face 

2. Similar nodular granulomas can occur in the pulmonary tree and other viscera

3. more common in people of black African descent

1. most commonly presents as follicle-based comedones, inflammatory papules, or pustules on the face, neck, chest, and back

2.  Occurs a lot in teenagers, however is seen adults as well. 

3. Open comedone or closed comedone