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CH 2 Human Anatomy
The Cell
50
Biology
Undergraduate 3
09/08/2011

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Term
When were cells first described and by whom?
Definition
1665
Robert Hooke
Term
What are the 3 components of the cell theory?
Definition
cells are the structural "building blocks" of all plants and animals
cells are produced by the division of preexisting cells
cells are the smallest structural units that perform all vital functions
Term
transmission electron microscopy
Definition
electrons penetrate ultra thin section of tissue to strike a photographic plate
shows fine structure of plasmalemma and intracellular structures
Term
scanning electron microscopy
Definition
electrons bounce off of exposed surfaces that have been coated with a gold-carbon film
provides 3D perspective
Term
What is the composition and function of the plasmalemma?
Definition
lipid bilayer (contains phospholipids, steroids, proteins and carbs)
isolation, protection, sensitivity, support, control of extrance/exit of materials
Term
What is the composition and function of the cytosol?
Definition
fluid component of the cytoplasm (may contain inclusions of insoluble material)
distributes materials by diffusion, stores glycogen, pigments, and other materials
Term
Name the 5 nonmembranous organelles.
Definition
ribosomes
microvilli
cilia
flagella
cytoskeleton
Term
Name the 6 membranous organelles.
Definition
mitochondria
nucleus
endoplasmic reticulum
golgi apparatus
lysosome
peroxisome
Term
What is the composition and function of the cytoskeleton?
Definition
membrane extensions containing microfilaments
increases surface area to facilitate absorption of extracellular materials
Term
What is the composition and function of the microvilli?
Definition
membrane extensions containing microtubule doubles in 9 + 2 array
move materials over cell surface
Term
What are the 2 general types of membrane proteins?
Definition
peripheral proteins
integral proteins
Term
peripheral proteins
Definition
membrane proteins that are attached either to the inner or the outer membrane surface
Term
integral proteins
Definition
membrane proteins embedded in the membrane
Term
transmembrane proteins
Definition
integral proteins that span the width of the membrane 1 or more times
Term
Passive vs active processes
Definition
passive move ions or molecules across plasmalemma with out using energy
active processes require that the cell draw on an energy source
Term
What are the 3 passive processes?
Definition
diffusion, osmosis, and facilitated diffusion
Term
What are the only 2 ways for an ion or molecule to DIFFUSE across a membrane?
Definition
through a channel or else by being lipid soluble
Term
facilitated diffusion
Definition
essential nutrients such as glucose and amino acids are passively transported across the membrane by special carrier proteins
Term
Why are active processes necessary?
Definition
to transport materials against the concentration gradient
Term
What are the 2 active processes?
Definition
active transport
endocytosis
Term
ion pumps
Definition
specialized mechanisms that move one specific cation or anion in one direction, either into or out of the cell
Term
exchange pump
Definition
specialized mechanism that moves one ion in one direction while the other ion is moved in the other direction
Term
endocytosis
Definition
packaging of extracellular materials into a vesicle at the cell surface for importation into the cell
Term
3 types of endocytosis
Definition
pinocytosis, phagocytosis, and receptor-mediated endocytosis
Term
pinocytosis
Definition
"cell drinking"
deep groove forms in membrane, pinches off, and materials diffuse from liquid into cell, then membrane returns to surface
Term
phagocytosis
Definition
"cell eating"
pseudopodia surround object, vesicle is formed, and contents are digested by lysosome
only in the immune system
Term
receptor-mediated endocytosis
Definition
produces coated vesicles with a target molecule in very high concentration
target material=ligand, bound to receptors on surface
Term
What are the 4 major components of the cytoskeleton?
Definition
microfilaments
intermediate filaments
thick filiments
microtubules
Term
What is the composition and function of centrioles?
Definition
9 groups of microtubule triplets to form a short cylinder, 9 + 0 array
organizes microtubules in the spindle to move chromosomes during cell division
Term
What is the composition and function of cilia?
Definition
9 groups of long microtubule doublets to form a cylinder around a central pair, 9 + 2 array
propels fluids or solids across cell surface
Term
What is the composition and function of flagella?
Definition
9 groups of microtubule doublets around central pair, 9 + 2 array
longer than cilia
whip-like motion
Term
2 types of ribosome and function of each:
Definition
fixed-proteins manufactured directly enter cytosol
wandering-proteins attach to ER and enter lumen to be packaged and processed
Term
mitochondria
Definition
double membrane
cristae (inner membrane)
manufacture ATP
not in RBCs
Term
nucleus
Definition
control center of cell
double membrane
control what proteins are synthesized and in what amounts
Term
endoplasmic reticulum
Definition
can be rough or smooth
have chambers called cisternae
4 functions: synthesis, storage, transport, detox
Term
rough ER
Definition
ribosomes attached, modify proteins synthesized
Term
smooth ER
Definition
no ribosomes associated
synthesize lipids, steroids, and carbs
store calcium ions
remove and inactivate toxins
Term
Golgi apparatus
Definition
consists of flattened discs called cisternae
functions: synthesize secretions, package special enzymes, and renew/modify plasmalemma
Term
lysosomes
Definition
vesicle produced within the Golgi, never leave cytoplasm
contain digestive enzymes
Term
peroxisomes
Definition
smaller than lysosomes, formed by free ribosomes
absorb/break down fatty acids & other organic products
mostly in liver cells
Term
cell adhesion molecules (CAMs)
Definition
transmembrane proteins that bind to each other and to other extracellular materials
Term
intercellular cement
Definition
thin layer of proteoglycans that hold together membranes of adjacent cells
Term
3 types of cell junctions:
Definition
tight
communicating
anchoring
Term
tight junctions (occluding junction)
Definition
lipid portions of the 2 plasmalemmae are bound together to seal off the the intercellular space between cells
Term
communicating junctions
Definition
two cells are held together by interlocked membrane proteins that are channel proteins, so a narrow passageway is formed for communication
Term
anchoring junction
Definition
provides a mechanical linkage between 2 adjacent cells at their lateral or basal surfaces
accomplished by CAMs and proteoglycans
Term
interphase
Definition
part of cell life cycle in which the cell is performing all normal functions and preparing for division if necessary
Term
stages of mitosis
Definition
prophase
metaphase
anaphase
telophase
Term
cytokinesis
Definition
division of the cytoplasm
Term
mitosis
Definition
nuclear division of somatic cells
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